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8 results

A Case of Masked t(8;21) in Acute Myeloid Leukemia with Cytogenetic Abnormality of 45,X,-Y,t(8;17)(q22;p13)

Shim H, Lee YJ

  • Lab Med Online.
  • 2011 Jul;1(3):168-171.
The t(8;21)(q22;q22) is one of the most frequent structural chromosomal anomaly found in AML, occurring in about 5% of all AML and in 10% of AML with maturation (M2). And...
A Case of Concomitant Inv(3)(q21q26) and Cryptic BCR/ABL1 Rearrangement in the Blast Crisis of Chronic Myeloid Leukemia

Lee H, Cho C, Kwon MJ, Nam MH, Lee CK, Kim YK

  • Lab Med Online.
  • 2011 Jul;1(3):163-167.
Structural abnormalities of the long arm of chromosome 3 (3q) have been associated with elevated platelet count and hyperplasia of megakaryocytes with dysplasia in various hematological malignancies. Some cases of...
Immunoglobulin Isotype Switching in a Plasma Cell Myeloma Patient Treated with High-dose Chemotherapy and Hematopoietic Stem Cell Transplantation

Ham JY, Lee KM, Song KE

  • Lab Med Online.
  • 2011 Jul;1(3):158-162.
A malignant plasma cell clone usually produces a single abnormal monoclonal protein with a constant isotype. However, switching of paraprotein isotype has been reported to be a transient phenomenon associated...
Re-evaluation of the Anti-streptolysin O Test for Systemic Rheumatic Diseases

Shin KS, Jearn LH, Kim TY

  • Lab Med Online.
  • 2011 Jul;1(3):153-157.
BACKGROUND: Anti-streptolysin O (ASO) test is usually used to diagnose group A streptococcal infection-related diseases, such as rheumatic fever, reactive arthritis, and various infectious diseases. Despite the recent declining incidence...
Reticulocyte Indices for the Differential Diagnosis of Anemia of Chronic Disease and Iron Deficiency Anemia in Adult Women with Microcytic Hypochromic Anemia

Park SH, Seo YH, Park PH, Kim KH, Song YH, Jung JH, Ahn JY

  • Lab Med Online.
  • 2011 Jul;1(3):147-152.
BACKGROUND: Iron deficiency anemia (IDA) is the most common anemia followed by anemia of chronic disease (ACD). Reticulocyte indices have been shown to be helpful indicators for detecting IDA. We...
Serial Determination of FLT3-ITD and NPM1 Mutations and Its Clinical Significance in Patients with MDS at Diagnosis and After Progression to AML with Myelodysplasia-related Changes

Chung JW, Chi HS, Lee EH, Jang S, Seo EJ, Park CJ

  • Lab Med Online.
  • 2011 Jul;1(3):138-146.
BACKGROUND: Accumulation of genetic aberrations in MDS is closely associated with progression to AML. FLT3-ITD is commonly found in AML and less frequently in MDS. FLT3-ITD in MDS is associated...
Usefulness of Thyroglobulin Measurement in Fine-needle Aspirates of Lymph Nodes for the Diagnosis of Lymph Node Metastasis of Papillary Thyroid Cancer

Hong DJ, Choi SJ, Kim S

  • Lab Med Online.
  • 2011 Jul;1(3):132-137.
BACKGROUND: Previous studies have shown that thyroglobulin (Tg) measurement in fine-needle aspirates (FNA) of lymph nodes can assist in evaluating cervical lymph node metastasis. In this study, we evaluated the...
Translation: Non-HDL Cholesterol Shows Improved Accuracy for Cardiovascular Risk Score Classification Compared to Direct or Calculated LDL Cholesterol in a Dyslipidemic Population

van Deventer HE, Miller WG, Myers GL, Sakurabayashi I, Bachmann L, Caudill SP, Dziekonski A, Edwards S, Kimberly M, Korzun WJ, Leary ET, Nakajima K, Nakamura M, Shamburek , Vetrovec G, Warnick GR, Remaley AT

  • Lab Med Online.
  • 2011 Jul;1(3):121-131.
BACKGROUND: Our objective was to evaluate the accuracy of cardiovascular disease (CVD) risk score classification by direct LDL cholesterol (dLDL-C), calculated LDL cholesterol (cLDL-C), and non-HDL cholesterol (non-HDL-C) compared to...

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