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7 results

Erratum: Protective effects of cultured and fermented ginseng extracts against scopolamine-induced memory loss in a mouse model

Han SH, Kim SJ, Yun YW, Nam SY, Lee HJ, Lee BJ

  • Lab Anim Res.
  • 2018 Sep;34(3):132-132.
  • doi: 10.5625/lar.2018.34.3.132
In the Materials and Methods section, material supply source is incorrectly cited and has been changed upon request of authors.
Neither polyphenol-rich red wine nor fenofibrate affects the onset of type-1 diabetes mellitus in the BB rat

Ã…vall K, Berggren P, Juntti-Berggren L

  • Lab Anim Res.
  • 2018 Sep;34(3):126-131.
  • doi: 10.5625/lar.2018.34.3.126
Serum levels of the pro-inflammatory apolipoprotein CIII (apoCIII) are increased in type-1 diabetic (T1D) patients and when β-cells are exposed to apoCIII they undergo apoptosis, which can be prevented by...
Successful development of squamous cell carcinoma and hyperplasia in RGEN-mediated p27 KO mice after the treatment of DMBA and TPA

Choi JY, Yun WB, Kim JE, Lee MR, Park JJ, Song BR, Kim HR, Park JW, Kang MJ, Kang BC, Lee HW, Hwang DY

  • Lab Anim Res.
  • 2018 Sep;34(3):118-125.
  • doi: 10.5625/lar.2018.34.3.118
To evaluate the carcinogenicity of p27 knockout (KO) mice with RNA-guided endonuclease (RGENs)-mediated p27 mutant exon I gene (IΔ), alterations in the carcinogenic phenotypes including tumor spectrum, tumor suppressor proteins,...
Inhibitory effects of Pycnogenol®, a pine bark extract, in a rat model of testosterone propionate-induced benign prostatic hyperplasia

Ko JW, Park SW, Shin NR, Kim WI, Kim JC, Shin IS, Shin DH

  • Lab Anim Res.
  • 2018 Sep;34(3):111-117.
  • doi: 10.5625/lar.2018.34.3.111
Benign prostate hyperplasia (BPH) is a male reproductive disease that has gained increasing importance in recent years. The present study investigated whether Pycnogenol® (PYC), a standardized French maritime pine bark...
Dose dependence and durability of the therapeutic effects of Asparagus cochinchinensis fermented extract in an ovalbumin-challenged asthma model

Choi JY, Park JW, Kim JE, Park JJ, Lee MR, Song BR, Kang MJ, Hwang DY

  • Lab Anim Res.
  • 2018 Sep;34(3):101-110.
  • doi: 10.5625/lar.2018.34.3.101
The butanol extract of Asparagus cochinchinensis roots fermented with Weissella cibaria (BAfW) significantly suppressed the inflammatory response induced by lipopolysaccharide (LPS) treatment in RAW264.7 cells. To investigate the dose dependence...
Protective effect of water extract of guibi-tang against pulmonary inflammation induced by cigarette smoke and lipopolysaccharide

Shin NR, Jung TY, Seo CS, Park SW, Ko JW, Kim JC, Shin IS

  • Lab Anim Res.
  • 2018 Sep;34(3):92-100.
  • doi: 10.5625/lar.2018.34.3.92
Water extract of guibi-tang (GB), a traditional Chinese, Japanese, and Korean herbal medicine, is used to treat memory impairment, insomnia, and peptic ulcers. The aim of this study was to...
Mouse models for hepatitis B virus research

Hwang JR, Park SG

  • Lab Anim Res.
  • 2018 Sep;34(3):85-91.
  • doi: 10.5625/lar.2018.34.3.85
Hepatitis B virus (HBV) infection remains a major global health problem; indeed, there are 250 million carriers worldwide. The host range of HBV is narrow; therefore, few primates are susceptible...

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