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Radiation-induced eosinophilic, polymorphic, and pruritic eruption in a pig skin model

Kim JS, Jang WS, Bae MJ, Park S, Lee SS

  • Lab Anim Res.
  • 2015 Dec;31(4):204-208.
  • doi: 10.5625/lar.2015.31.4.204
Eosinophilic, polymorphic and pruritic eruption associated with radiotherapy (EPPER) can occur in cancer patients after irradiation. In this study, we characterized the clinical and histopathological features of pig skin that...
Curcumin attenuates the middle cerebral artery occlusion-induced reduction in gamma-enolase expression in an animal model

Gim SA, Lee SR, Shah FA, Koh PO

  • Lab Anim Res.
  • 2015 Dec;31(4):198-203.
  • doi: 10.5625/lar.2015.31.4.198
Curcumin exerts a protective effect in cerebral ischemia through its anti-oxidant and anti-inflammatory activities. gamma-enolase is a glycolytic enzyme expressed in neurons that is known to exerts a neuroprotective effect....
Tissue transglutaminase-interleukin-6 axis facilitates peritoneal tumor spreading and metastasis of human ovarian cancer cells

Oh K, Moon HG, Lee DS, Yoo YB

  • Lab Anim Res.
  • 2015 Dec;31(4):188-197.
  • doi: 10.5625/lar.2015.31.4.188
Inflammation has recently been implicated in cancer formation and progression. As tissue transglutaminase (TG2) has been associated with both inflammatory signaling and tumor cell behavior, we propose that TG2 may...
Supraphysiologic glucocorticoid administration increased biomechanical bone strength of rats' vertebral body

Najar A, Fridoni M, Rezaei F, Bayat S, Bayat M

  • Lab Anim Res.
  • 2015 Dec;31(4):180-187.
  • doi: 10.5625/lar.2015.31.4.180
The aim of this study is to assess the effects of different glucocorticoid administration protocols on biomechanical properties of the first lumbar vertebral body in rats. We divided 40 male...
Intraperitoneal co-administration of low dose urethane with xylazine and ketamine for extended duration of surgical anesthesia in rats

Kumar AH, Clover AJ

  • Lab Anim Res.
  • 2015 Dec;31(4):174-179.
  • doi: 10.5625/lar.2015.31.4.174
Procedures involving complex surgical techniques in rats, such as placement of abdominal aortic graft require extended duration of surgical anesthesia, which often can be achieved by repeated administrations of xylazine-ketamine...
Comparative analysis of growth characteristics of Sprague Dawley rats obtained from different sources

Brower M, Grace M, Kotz CM, Koya V

  • Lab Anim Res.
  • 2015 Dec;31(4):166-173.
  • doi: 10.5625/lar.2015.31.4.166
Genetic background in animal models is an intrinsic research variable in biomedical research. Although inbred strains offer genetic uniformity, the outbred stocks, known for genetic variability are often used to...
Modeling Parkinson's disease in the common marmoset (Callithrix jacchus): overview of models, methods, and animal care

Yun JW, Ahn JB, Kang BC

  • Lab Anim Res.
  • 2015 Dec;31(4):155-165.
  • doi: 10.5625/lar.2015.31.4.155
The common marmoset (Callithrix jacchus) is a small-bodied, popular New World monkey and is used widely in reproductive biology, neuroscience, and drug development, due to its comparative ease of handling,...

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