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Experimental model of tympanic colic (acute abdomen) in chinchillas (Chinchilla lanigera)

Martinez-Pereira MA, Franceschi RdC, Coelho BP, Funkler GD, Zancan DM

  • Lab Anim Res.
  • 2014 Sep;30(3):136-141.
  • doi: 10.5625/lar.2014.30.3.136
Digestive disorders caused by sudden changes in diet or inappropriate diet are among the most common disorders of the digestive system. Cecal or intestinal tympany, one consequence of inappropriate diet,...
Anti-Helicobacter pylori activities of FEMY-R7 composed of fucoidan and evening primrose extract in mice and humans

Kim TS, Choi EK, Kim J, Shin K, Lee SP, Choi Y, Jeon JH, Kim YB

  • Lab Anim Res.
  • 2014 Sep;30(3):131-135.
  • doi: 10.5625/lar.2014.30.3.131
Helicobacter pylori-eliminating effects of FEMY-R7, composed of fucoidan and evening primrose extract, were investigated in mice and humans. Male C57BL/6 mice were infected with the bacteria by intragastric inoculation (1x10(9)...
Adverse effects of 4-tert-octylphenol on the production of oxytocin and hCG in pregnant rats

Kim J, Kang EJ, Park MN, Lee JE, Hong SH, An SM, Kim SC, Hwang DY, An BS

  • Lab Anim Res.
  • 2014 Sep;30(3):123-130.
  • doi: 10.5625/lar.2014.30.3.123
Endocrine-disrupting chemicals (EDCs) are exogenous substances that alter the structure or function of the endocrine system. 4-Tert-octylphenol (OP) is one of the most representative EDCs and has estrogenic effects. In...
13-week subchronic toxicity study of a novel ginsenoside composition from ginseng leaves in rats

Shin WH, Ri Y, Do SG, Lee YC, Park SJ

  • Lab Anim Res.
  • 2014 Sep;30(3):112-122.
  • doi: 10.5625/lar.2014.30.3.112
UG0712 is a new ginsenoside extract processed from ginseng leaves. A subchronic toxicity study of UG0712 was conducted in male and female SD rats. Rats were treated with UG0712 at...
Evaluation of the genotoxicity of ginseng leaf extract UG0712

Kim JY, Ri Y, Do SG, Lee YC, Park SJ

  • Lab Anim Res.
  • 2014 Sep;30(3):104-111.
  • doi: 10.5625/lar.2014.30.3.104
Although ginseng (genus Panax) leaf extract contains high concentrations of bioactive constituents, its effects have been reported in few preclinical studies, and information regarding its toxicity is not sufficient to...
Characterization of allergic response induced by repeated dermal exposure of IL-4/Luc/CNS-1 transgenic mice to low dose formaldehyde

Kwak MH, Kim JE, Go J, Koh EK, Song SH, Sung JE, Yang SY, An BS, Jung YJ, Lee JH, Lim Y, Hwang DY

  • Lab Anim Res.
  • 2014 Sep;30(3):95-103.
  • doi: 10.5625/lar.2014.30.3.95
Although formaldehyde (FA) is known to be a major allergen responsible for allergic contact dermatitis, there are conflicting reports regarding correlation between FA exposure and interleukin (IL-4) expression. To investigate...

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