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7 results

No expression of porcine endogenous retrovirus after pig to monkey xenotransplantation

Hwang S, Jung YD, Cho K, Ock SA, Oh KB, Kim HS, Yun IJ, Ahn C, Park JK, Im S

  • Lab Anim Res.
  • 2014 Jun;30(2):90-93.
  • doi: 10.5625/lar.2014.30.2.90
This study was performed to investigate the expression of two porcine endogenous retrovirus (PERV) elements, PERV gag and full-length conserved PERV, in blood cells collected periodically from organ-recipient monkeys that...
An ethanolic extract of Angelica gigas improves atherosclerosis by inhibiting vascular smooth muscle cell proliferation

Jang JY, Kim J, Cai J, Kim Y, Shin K, Kim TS, Lee SP, Park SK, Choi EK, Kim YB

  • Lab Anim Res.
  • 2014 Jun;30(2):84-89.
  • doi: 10.5625/lar.2014.30.2.84
The effects of an ethanolic extract of Angelica gigas (EAG) on the vascular smooth muscle cell (VSMC) proliferation and high-cholesterol diet-induced hypercholesterolemia and atherosclerosis were investigated. Rat aortic VSMCs were...
The potential mechanism of the detrimental effect of defibrillation prior to cardiopulmonary resuscitation in prolonged cardiac arrest model

Bae JH, Park CW, Cho JH, Kim YS, Lee HY, Won MH

  • Lab Anim Res.
  • 2014 Jun;30(2):79-83.
  • doi: 10.5625/lar.2014.30.2.79
Defibrillation is no longer universally recommended as initial intervention for the reversal of ventricular fibrillation (VF) after a prolonged and untreated cardiac arrest. We sought to examine this issue in...
Effects of anti-obesity drugs, phentermine and mahuang, on the behavioral patterns in Sprague-Dawley rat model

Go RE, Hwang KA, Kim SH, Lee MY, Kim CW, Jeon SY, Kim YB, Choi KC

  • Lab Anim Res.
  • 2014 Jun;30(2):73-78.
  • doi: 10.5625/lar.2014.30.2.73
According to WHO global estimates from 2008, more than 1.4 billion adults were overweight and among them, over 200 million men and 300 million women were obese. Although the main...
Establishment of linear accelerator-based image guided radiotherapy for orthotopic 4T1 mouse mammary tumor model

Lee SH, Kim JY, Lee KC, Nam JS, Choi J, Lee SH, Sung KH, Ahn SH

  • Lab Anim Res.
  • 2014 Jun;30(2):64-72.
  • doi: 10.5625/lar.2014.30.2.64
This study was conducted to assess the feasibility of image guided radiotherapy (IGRT) for orthotopic 4T1 mouse mammary tumor using linear accelerator (LINAC). Eighteen Balb/C mice were inoculated with 4T1...
Toxicity of fermented soybean product (cheonggukjang) manufactured by mixed culture of Bacillus subtilis MC31 and Lactobacillus sakei 383 on liver and kidney of ICR mice

Lee YJ, Kim JE, Kwak MH, Go J, Son HJ, Kim DS, Kang BC, Lee HS, Hwang DY

  • Lab Anim Res.
  • 2014 Jun;30(2):54-63.
  • doi: 10.5625/lar.2014.30.2.54
To investigate the toxic effects of cheonggukjang (CKJ) manufactured using mixed cultures of Bacillus subtilis MC31 and Lactobacillus sakei 383 on the liver and kidney of ICR mice, an alteration...
Proteomic analysis of domestic pig pancreas during development using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry

Ahn JY, Kim IY, Oh SJ, Hwang HS, Yi SS, Kim YN, Shin JH, Yoon YS, Seong JK

  • Lab Anim Res.
  • 2014 Jun;30(2):45-53.
  • doi: 10.5625/lar.2014.30.2.45
Pig pancreas may be a therapeutic resource for human diabetic patients. However, this potential is hindered by a lack of knowledge of the molecular events of pig pancreas development. In...

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