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8 results

Uterine leiomyosarcoma in a wild rat (Rattus norvegicus): usefulness of Ki-67 labeling index for diagnosis

Jeon BS, Kim HG, Lee BW, Han JH, Yoon BI

  • Lab Anim Res.
  • 2013 Jun;29(2):127-130.
  • doi: 10.5625/lar.2013.29.2.127
Uterine smooth muscle tumor is very rare in laboratory rats and, there has been no report in the wild rodents. Among a total of 400 wild rats captured in Gyeonggi,...
In vitro and in vivo study of effects of fermented soybean product (chungkookjang) on NGF secretion ability and NGF receptor signaling pathway

Lee YJ, Kim JE, Kwak MH, Go J, Son HJ, Kim DS, Hwang DY

  • Lab Anim Res.
  • 2013 Jun;29(2):113-126.
  • doi: 10.5625/lar.2013.29.2.113
In order to investigate the effects of a fermented soybean product (Chungkookjang, CKJ) on nerve growth factor (NGF) metabolism, NGF secretion ability and its related signaling pathway were analyzed in...
Therapeutic effects of fermented soycrud on phenotypes of atopic dermatitis induced by phthalic anhydride

Sung JE, Kwak MH, Kim JE, Lee YJ, Kim RU, Kim EA, Lee GY, Kim DS, Hwang DY

  • Lab Anim Res.
  • 2013 Jun;29(2):103-112.
  • doi: 10.5625/lar.2013.29.2.103
Atopic dermatitis (AD), which is known as the most common pruritic skin disease, is caused by epidermal barrier dysfunction, allergies, microwave radiation, histamine intolerance, and genetic defects. To investigate the...
Rabbit gastric ulcer models: comparison and evaluation of acetic acid-induced ulcer and mucosectomy-induced ulcer

Maeng JH, Lee E, Lee DH, Yang SG

  • Lab Anim Res.
  • 2013 Jun;29(2):96-102.
  • doi: 10.5625/lar.2013.29.2.96
In this study, we examined rabbit gastric ulcer models that can serve as more clinically relevant models. Two types of ulcer model were studied: acetic acid-induced ulcers (AAU) and mucosal...
Red Liriope platyphylla stimulated the insulin secretion through the regulation of calcium concentration in rat insulinoma cells and animal models

Lee HR, Kim JE, Lee YJ, Kwak MH, Im DS, Hwang DY

  • Lab Anim Res.
  • 2013 Jun;29(2):84-95.
  • doi: 10.5625/lar.2013.29.2.84
The aim of this study was to investigate the effects of Red L. platyphylla (RLP) on calcium and glucose levels during insulin secretion. To achieve this, alteration of insulin and...
Quantitative and qualitative analysis of rat pup ultrasonic vocalization sounds induced by a hypothermic stimulus

Kromkhun P, Katou M, Hashimoto , Terada M, Moon C, Saito TR

  • Lab Anim Res.
  • 2013 Jun;29(2):77-83.
  • doi: 10.5625/lar.2013.29.2.77
Ultrasonic vocalizations (USVs) are essential communicative sounds used between rodent pups and their mother. Rat pups emit USVs in stressful situations, such as when they are cold or separated from...
Treatment of eggshell with casein phosphopeptide reduces the severity of ovariectomy-induced bone loss

Kim JH, Kim MS, Oh HG, Lee HY, Park JW, Lee BG, Park SH, Moon DI, Shin EH, Oh EK, Erkhembaatar M, Kim O, Lee YR, Chae HJ

  • Lab Anim Res.
  • 2013 Jun;29(2):70-76.
  • doi: 10.5625/lar.2013.29.2.70
It has been generally accepted that calcium intake prevents bone loss, and frequent fracture resulted from osteoporosis. However, it is still elusive as to how effective sole calcium intake is...
Ferulic acid regulates the AKT/GSK-3beta/CRMP-2 signaling pathway in a middle cerebral artery occlusion animal model

Gim SA, Sung JH, Shah FA, Kim MO, Koh PO

  • Lab Anim Res.
  • 2013 Jun;29(2):63-69.
  • doi: 10.5625/lar.2013.29.2.63
Ferulic acid, a component of the plants Angelica sinensis (Oliv.) Diels and Ligusticum chuanxiong Hort, exerts a neuroprotective effect by regulating various signaling pathways. This study showed that ferulic acid...

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