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13 results

Focal Cerebral Ischemia Reduces Protein Phosphatase 2A Subunit B Expression in Brain Tissue and HT22 Cells

Koh PO

  • Lab Anim Res.
  • 2011 Mar;27(1):73-76.
Protein phosphatase 2A (PP2A) is a serine and threonine protein phosphatase that regulates cell cycle progression and apoptosis. PP2A is composed of various subunits. Among these subunits, subunit B plays...
Neuroprotection of Alpinia katsumadai Seed Extract against Neuronal Damage in the Ischemic Gerbil Hippocampus is Linked to Altered Brain-Derived Neurotrophic Factor

Li H, Park JH, Yan B, Yoo KY, Lee CH, Choi JH, Hwang IK, Won MH

  • Lab Anim Res.
  • 2011 Mar;27(1):67-71.
The extract of Alpinia katsumadai, a member of the family Zingiberaceae, shows anti-inflammatory effects and antioxidant activity. We observed the neuroprotective effects of the extract from Alpinia katsumadai seed (EAKS)...
Mural Folliculitis and Alopecia with Cutaneous Candidiasis in a Beagle Dog

Lee HA, Hong S, Choe O, Kim O

  • Lab Anim Res.
  • 2011 Mar;27(1):63-65.
A one-year-old male Beagle dog showed dermatitis, alopecia and scales. Examination of the affected dog revealed generalized alopecia, patchy erythema, and superficial erosions with histological evidence of mural folliculitis. External...
Cronobacter sakazakii Infection Induced Fatal Clinical Sequels Including Meningitis in Neonatal ICR Mice

Lee HA, Hong S, Park H, Kim H, Kim O

  • Lab Anim Res.
  • 2011 Mar;27(1):59-62.
Cronobacter sakazakii (C. sakazakii), formerly Enterobacter sakazakii, is an emerging pathogen associated with the ingestion of contaminated reconstituted formula that causes serious illnesses such as bacteremia, septicemia, necrotizing enterocolitis, meningitis...
Chordoma in the Tail of a Ferret

Cho ES, Kim JY, Ryu SY, Jung JY, Park BK, Son HY

  • Lab Anim Res.
  • 2011 Mar;27(1):53-57.
A chordoma is an uncommon tumor that originates from the remnants of the notochord and most commonly involves the cranial and caudal regions of the axial skeleton. Chordoma has been...
Different Antiulcer Activities of Pantoprazole in Stress, Alcohol and Pylorus Ligation-Induced Ulcer Models

Bae DK, Park D, Lee SH, Yang G, Yang YH, Kim TK, Choi YJ, Kim JJ, Jeon JH, Jang MJ, Choi EK, Hwang SY, Kim YB

  • Lab Anim Res.
  • 2011 Mar;27(1):47-52.
Antiulcer effects of pantoprazole, a proton-pump inhibitor, on water-immersion restraint stress (WIRS)-, alcohol (ethanol)- and pylorus ligation-induced gastric ulcers were investigated in male rats. Rats were orally administered with pantoprazole...
Mapping of the Faded (fe) Gene to a Region between D10mit191 and D10mit44 on Mouse Chromosome 10

Oh SH, Nam Y, Suh JG

  • Lab Anim Res.
  • 2011 Mar;27(1):41-46.
The faded mouse is a coat color mutant that shows faded coat color and age-related loss of pigmentation. This mutation is transmitted by an autosomal recessive gene with 100% penetrance....
Determination of Oxyclozanide in Beef and Milk using High-Performance Liquid Chromatography System with UV Detector

Jo K, Cho HJ, Yi H, Cho SM, Park JA, Kwon CH, Park HR, Kwon KS, Shin HC

  • Lab Anim Res.
  • 2011 Mar;27(1):37-40.
This study was developed and validated for the determination of oxyclozanide residue concentrations in beef and commercial milk, using high-performance liquid chromatography system. Oxyclozanide was successfully separated on a reverse...
Overexpression of Insulin Degrading Enzyme could Greatly Contribute to Insulin Down-regulation Induced by Short-Term Swimming Exercise

Kim MS, Goo JS, Kim JE, Nam SH, Choi SI, Lee HR, Hwang IS, Shim SB, Jee SW, Lee SH, Bae CJ, Cho JS, Cho JY, Hwang DY

  • Lab Anim Res.
  • 2011 Mar;27(1):29-36.
Exercise training is highly correlated with the reduced glucose-stimulated insulin secretion (GSIS), although it enhanced insulin sensitivity, glucose uptake and glucose transporter expression to reduce severity of diabetic symptoms. This...
Increased Nephrotoxicity after Combined Administration of Melamine and Cyanuric Acid in Rats

Park D, Kim TK, Choi YJ, Lee SH, Bae DK, Yang G, Yang YH, Joo SS, Choi EK, Ahn B, Kim JC, Kim KS, Kim YB

  • Lab Anim Res.
  • 2011 Mar;27(1):25-28.
Renal toxicity by melamine in combination with cyanuric acid (1:1) was investigated. Male rats were orally administered melamine plus cyanuric acid (5, 50 or 400 mg/kg each) for 3 days....
The Apoptotic Effect of the Hexane Extract of Rheum undulatum L. in Oral Cancer Cells through the Down-regulation of Specificity Protein 1 and Survivin

Choi ES, Cho SD, Jeon JG, Cho NP

  • Lab Anim Res.
  • 2011 Mar;27(1):19-24.
The hexane extract of Rheum undulatum L. (HERL) has been shown to have anti-cancer activity in several cancers in vivo and in vitro. However, the anti-cancer activity of HERL and...
Effects of Selenium on Colon Carcinogenesis Induced by Azoxymethane and Dextran Sodium Sulfate in Mouse Model with High-Iron Diet

Kim JH, Hue JJ, Kang BS, Park H, Nam SY, Yun YW, Kim JS, Lee BJ

  • Lab Anim Res.
  • 2011 Mar;27(1):9-18.
Selenium (Se) is known to prevent several cancers while the relationship between high iron and the risk of colorectal cancer is controversial. To investigate the effects of Se in colon...
Molecular Mechanisms and In Vivo Mouse Models of Skin Aging Associated with Dermal Matrix Alterations

Hwang KA, Yi BR, Choi KC

  • Lab Anim Res.
  • 2011 Mar;27(1):1-8.
Skin is the most superficial body organ and plays an important role in protecting the body from environmental damage and in forming social relations. With the increase of the aging...

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