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15 results

Postpartum Transmission as a Major Route of Mother-to-Child Helicobacter felis Infection

Hong S, Lee HA, Kim Y, Kim O

  • Lab Anim Res.
  • 2010 Sep;26(3):319-321.
In this study we investigated maternal Helicobacter felis (H. felis) infection status to determine the potential of maternal transmission. Pregnant Beagle dogs were infected experimentally with H. felis. Following the...
Morphometric Analysis of Tibial Bone in Three Strains of Mice Using Micro-computed Tomography

Ahn BS, Kim JS, Lee CG, Yang M, Moon C, Kim JC, Jung U, Kim SH

  • Lab Anim Res.
  • 2010 Sep;26(3):315-318.
This study investigated the trabecular and cortical bone microarchitecture of tibia in 14-week-old C3H/HeN, C57BL/6J and ICR mice using micro-computed tomography (micro-CT). Defined volumes of interest were scanned at a...
Focal Cerebral Ischemia Induces Decrease of Astrocytic Phosphoprotein PEA-15 in Brain Tissue and HT22 Cells

Koh PO

  • Lab Anim Res.
  • 2010 Sep;26(3):311-314.
PEA-15 is a small phosphoprotein (15 kDa) that is enriched in brain astrocytes. PEA-15 acts as an important modulator of cellular function including apoptosis and signal integration. This study investigated...
Platynosomum fastosum Infestation in a Domestic Cat in Korea

Kim JM, Che JH, Jeong DH, Kang BC

  • Lab Anim Res.
  • 2010 Sep;26(3):307-309.
Cat liver fluke (Platynosomum fastosum) was identified upon necropsy of a Felis catus (domestic cat). This trematode has not been reported in domestic cats previously in Korea. Diagnosis of this...
Laser Capture Microdissection Reveals Specific Genes Related to Purkinje Cell Death in the Leaner Mice

Nahm SS, Yoo JE, Abbott LC

  • Lab Anim Res.
  • 2010 Sep;26(3):301-305.
The leaner mouse carries a mutation in the gene encoding the alpha1A subunit of P/Q-type calcium channels. Leaner mice exhibit extensive cerebellar granule and Purkinje cell loss that results in...
Dietary Selenium Supplement Prevents Colon Carcinogenesis Induced by Azoxymethane and Dextran Sodium Sulfate in ICR Mice

Kim JH, Hue JJ, Kang BS, Park H, Nam SY, Yun YW, Kim JS, Jeong JH, Lee BJ

  • Lab Anim Res.
  • 2010 Sep;26(3):293-300.
The role of selenium (Se) in modulating colon carcinogenesis induced by azoxymethane (AOM) followed by dextran sodium sulfate (DSS) was investigated in mice. Five-week old ICR mice were fed on...
Effects of a Silkworm Extract on Dopamine and Monoamine Oxidase-B Activity in an MPTP-induced Parkinsons Disease Model

Kang YK, Oh HS, Cho YH, Kim YJ, Han YG, Nam SH

  • Lab Anim Res.
  • 2010 Sep;26(3):287-292.
The protective efficacy of a silkworm extract (SE) on N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism and its possible mechanisms were studied in C57BL/6 mice. Mice were administrated intraperitoneally with SE (20 mg/kg/day) for...
Enhancement of Exercise Capacity by Black Ginseng Extract in Rats

Jo GS, Chai HY, Ji HJ, Kang MH, Kang SJ, Ji JG, Kim DJ, Lee BJ

  • Lab Anim Res.
  • 2010 Sep;26(3):279-286.
This study was carried out to investigate an enhancing effect of black ginseng extract (BGE) on exercise capacity in an endurance exercising animal model. Fifty Sprague-Dawley rats were assigned to...
Tissue Specific Expression of Lipid Metabolism Related Molecules in Digestive Organs of Miniature Pigs

Han HJ, Kang SS, Park SH

  • Lab Anim Res.
  • 2010 Sep;26(3):273-278.
The miniature pig is a very suitable donor species in xenotransplantation of human organs. Lipid metabolism is an important process that involves the creation and degradation of lipids, which is...
Inhibitory Effects of Korean Red Ginseng Extract on Atopic Dermatitis in NC/Nga Mice

Kim HS, Oh TH, Song JC, Kim DI, Lim AK, Yang DC, In JG, Kim YC, Kim KS

  • Lab Anim Res.
  • 2010 Sep;26(3):265-271.
Atopic dermatitis (AD) is a chronic eczematous skin disease attended by pruritus, erythema, edema, excoriation, and dryness. This study was to evaluate the effects of Korean red ginseng (RG) on...
Antibacterial Activity of Sanguisorba officinalis against Helicobacter pylori

Lee HA, Hong S, Oh HG, Park SH, Kim YC, Park H, Jeong GS, Kim O

  • Lab Anim Res.
  • 2010 Sep;26(3):257-263.
In this study, a medicinal herbal plant, Sanguisorba officinalis, was examined and screened for anti-Helicobacter pylori (H. pylori) activity. Seventy percent ethanol was used for herbal extraction. For anti-H. pylori...
Microbiological Contamination of Laboratory Mice and Rats in Korea from 2007 to 2008

Won YS, Kwon HJ, Kim SW, Han JT, Lee SB, Nam KH, Yoon WK, Kim KH, Moon OS, Kim HC

  • Lab Anim Res.
  • 2010 Sep;26(3):249-255.
In order to assess the microbiological contamination of laboratory mice and rats in Korea over the 2-year period from 2007 to 2008, we monitored animals housed in mouse and rat...
Evaluation on Efficacy and Safety of Tribromoethanol and Tribromoethanol plus alpha2-Adrenergic Agonists in Different Mouse Strains

Cho YJ, Lee JW, Kim JI, Lee YA, Kim TY, Han JS

  • Lab Anim Res.
  • 2010 Sep;26(3):241-247.
The present study was carried out to provide a guideline for injecting tribromoethanol (TBE) as the main anesthetic agent, while adjusting the doses of xylazine (X) and medetomidine (M) according...
The Bone Grinding and Scaffold Grafting Techniques for Guide Bone Regeneration Induce the Stress on the Rat Brain

Lee YK, Kim JE, Nam SH, Choi SI, Lee EP, Choi HW, Kim HS, Lee JH, Jung YJ, Kang BC, Cho JS, Hwang DY

  • Lab Anim Res.
  • 2010 Sep;26(3):233-239.
Guided bone regeneration (GBR) is a technique that a barrier membrane is placed over the bone defect to prevent the cell growth from the connective tissue and epithelium. In this...
Neuronal Hyperexcitability Mediates Below-Level Central Neuropathic Pain after Spinal Cord Injury in Rats

Park ES, Jeon Y, Cho DC, Youn DH, Gwak YS

  • Lab Anim Res.
  • 2010 Sep;26(3):225-232.
Spinal cord injury often leads to central neuropathic pain syndromes, such as allodynic and hyperalgesic behaviors. Electrophysiologically, spinal dorsal horn neurons show enhanced activity to non-noxious and noxious stimuli as...

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