- Corrigendum: Improved Urothelial Cell Proliferation, Cytoskeleton and Barrier Function Protein Expression in the Patients With Interstitial Cystitis/Bladder Pain Syndrome After Intravesical Platelet-Rich Plasma Injection
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Jhang JF, Jiang YH, Hsu YH, Ho HC, Birder LA, Lin TY, Kuo HC
- KMID: 2531422
- Int Neurourol J.
- 2022 Jun;26(2):169-169.
- doi: 10.5213/inj.2221050.corrigendum
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- Frontiers in the Clinical Applications of Botulinum Toxin A as Treatment for Neurogenic Lower Urinary Tract Dysfunction
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Jiang YH, Chen SF, Kuo HC
- KMID: 2510837
- Int Neurourol J.
- 2020 Dec;24(4):301-312.
- doi: 10.5213/inj.2040354.177
Patients with neurogenic lower urinary tract dysfunction (NLUTD) experience urinary incontinence with or without difficult urination, which might promote recurrent urinary tract infection (UTI) and exacerbate upper urinary tract function.... -
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- Recent Investigations of Urinary Nerve Growth Factor as a Biomarker for Overactive Bladder Syndrome
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Kuo HC
- KMID: 2314752
- Korean J Urol.
- 2009 Sep;50(9):831-835.
PURPOSE: Overactive bladder (OAB) is a symptom syndrome and is usually diagnosed by subjective symptoms of urgency with or without urgency incontinence. However, because urgency symptoms are so subjective, it... -
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- Clinical application of intravesical botulinum toxin type A for overactive bladder and interstitial cystitis
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Chen JL, Kuo HC
- KMID: 2469124
- Investig Clin Urol.
- 2020 Feb;61(Suppl 1):S33-S42.
- doi: 10.4111/icu.2020.61.S1.S33
After decades of clinical and basic science research, the clinical application of botulinum toxin A (Botox) in urology has been extended to neurogenic detrusor overactivity (NDO), idiopathic detrusor overactivity, refractory... -
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- Improved Urothelial Cell Proliferation, Cytoskeleton and Barrier Function Protein Expression in the Patients With Interstitial Cystitis/Bladder Pain Syndrome After Intravesical Platelet-Rich Plasma Injection
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Jhang JF, Jiang YH, Hsu YH, Ho HC, Birder LA, Lin TY, Kuo HC
- KMID: 2526665
- Int Neurourol J.
- 2022 Feb;26(Suppl 1):S57-67.
- doi: 10.5213/inj.2142100.050
Purpose: To investigate urothelial cell proliferation, cytoskeleton, inflammation, and barrier function protein expressions in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) after intravesical platelet-rich plasma (PRP) injections Methods: A total of... -
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- In Silico Sequence Analysis Reveals New Characteristics of Fungal NADPH Oxidase Genes
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Detry N, Choi J, Kuo HC, Asiegbu FO, Lee YH
- KMID: 2312753
- Mycobiology.
- 2014 Sep;42(3):241-248.
- doi: 10.5941/MYCO.2014.42.3.241
NADPH oxidases (Noxes), transmembrane proteins found in most eukaryotic species, generate reactive oxygen species and are thereby involved in essential biological processes. However, the fact that genes encoding ferric reductases... -
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- Pathomechanism of Interstitial Cystitis/Bladder Pain Syndrome and Mapping the Heterogeneity of Disease
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Jhang JF, Kuo HC
- KMID: 2362502
- Int Neurourol J.
- 2016 Nov;20(Suppl 2):S95-S104.
- doi: 10.5213/inj.1632712.356
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a heterogeneous syndrome which is usually characterized by urinary frequency, nocturia, and bladder pain. Several pathomechanisms have been proposed, including uroepithelial dysfunction, mast cell... -
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- Therapeutic Efficacy of Urethral Sphincter Injections of Platelet-Rich Plasma for the Treatment of Stress Urinary Incontinence due to Intrinsic Sphincter Deficiency: A Proof-of-Concept Clinical Trial
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Jiang YH, Lee PJ, Kuo HC
- KMID: 2514215
- Int Neurourol J.
- 2021 Mar;25(1):51-58.
- doi: 10.5213/inj.2040272.136
Purpose: The aim of this study was to investigate the efficacy of autologous platelet-rich plasma (PRP) in the treatment of stress urinary incontinence (SUI) due to intrinsic sphincter deficiency (ISD)... -
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- Therapeutic Efficacy of a New Procedure for Male Urinary Incontinence Combining a Suburethral Polypropylene Mesh and Cardiovascular Patch
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Wu SY, Jiang YH, Kuo HC
- KMID: 2375592
- Int Neurourol J.
- 2017 Mar;21(1):38-45.
- doi: 10.5213/inj.1732638.319
PURPOSE: Stress urinary incontinence (SUI) in men is a complication secondary to prostatectomy or resulting from neurological lesions. This study presents our experiences with male suburethral slings over the past... -
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- Lower Levels of Urinary Nerve Growth Factor Might Predict Recurrent Urinary Tract Infections in Women
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Chuang FC, Liu HT, Kuo HC
- KMID: 2173125
- Int Neurourol J.
- 2016 Mar;20(1):33-39.
- doi: 10.5213/inj.1630454.227
PURPOSE: To investigate the changes in urinary nerve growth factor (uNGF) levels after acute urinary tract infection (UTI) and to assess the role of uNGF in predicting UTI recurrence in... -
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- Urothelial Dysfunction and Chronic Inflammation are Associated With Increased Bladder Sensation in Patients With Chronic Renal Insufficiency
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Cheng SF, Jiang YH, Kuo HC
- KMID: 2405271
- Int Neurourol J.
- 2018 Jan;22(Suppl 1):S46-S54.
- doi: 10.5213/inj.1832814.407
PURPOSE: Chronic kidney disease (CKD) or end-stage renal disease (ESRD) patients usually have lower urinary tract symptoms, such as frequency and urgency. Additionally, they frequently suffer from urinary tract infections.... -
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- Long-term Outcomes of Augmentation Enterocystoplasty in Patients With End-Stage Bladder Diseases: A Single-Institute Experience Involving 102 Patients
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Wu SY, Jiang YH, Kuo HC
- KMID: 2387175
- Int Neurourol J.
- 2017 Jun;21(2):133-138.
- doi: 10.5213/inj.1732708.354
PURPOSE: Augmentation enterocystoplasty (AE) has been shown to improve clinical symptoms in patients with end-stage bladder disease (ESBD). Herein, we report the long-term outcomes of a series of patients with... -
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- The Overactive Bladder Symptom Score, International Prostate Symptom Score–Storage Subscore, and Urgency Severity Score in Patients With Overactive Bladder and Hypersensitive Bladder: Which Scoring System is Best?
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Chuang FC, Hsiao SM, Kuo HC
- KMID: 2417782
- Int Neurourol J.
- 2018 Jun;22(2):99-106.
- doi: 10.5213/inj.1832554.277
PURPOSE: To evaluate the correlations among the Overactive Bladder Symptom Score (OABSS), International Prostate Symptom Score–Storage Subscore (IPSS-S), and the modified Urgency Severity Scale (USS) in patients with overactive bladder... -
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- Practical Aspects of Botulinum Toxin-A Treatment in Patients With Overactive Bladder Syndrome
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Liao CH, Kuo HC
- KMID: 2380854
- Int Neurourol J.
- 2015 Dec;19(4):213-219.
- doi: 10.5213/inj.2015.19.4.213
Intravesical onabotulinumtoxinA (BoNT-A) injection is an effective treatment for overactive bladder syndrome (OAB) that is refractory to antimuscarinics. An injectable dose of 100 U has been suggested to achieve the... -
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- Duration of Antimuscarinic Administration for Treatment of Overactive Bladder Before Which One Can Assess Efficacy: An Analysis of Predictive Factors
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Hsiao SM, Liao CH, Lin HH, Kuo HC
- KMID: 2380846
- Int Neurourol J.
- 2015 Sep;19(3):171-177.
- doi: 10.5213/inj.2015.19.3.171
PURPOSE: To determine the duration of antimuscarinic therapy for overactive bladder syndrome (OAB) appropriate for assessment of the efficacy of treatment, and to evaluate the possible predictive factors for response... -
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- Abnormal Sensory Protein Expression and Urothelial Dysfunction in Ketamine-Related Cystitis in Humans
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Tsai YC, Birder L, Kuo HC
- KMID: 2365712
- Int Neurourol J.
- 2016 Sep;20(3):197-202.
- doi: 10.5213/inj.1632634.317
PURPOSE: The aim of this study was to analyze patterns of sensory protein expression and urothelial dysfunction in ketamine-related cystitis (KC) in humans. METHODS: Biopsies of bladder mucosa were performed in... -
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- Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50 mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms – A Multicenter, Randomized Study
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Lin CC, Kuo HC, Li JR, Chuang YC
- KMID: 2546082
- Int Neurourol J.
- 2023 Sep;27(3):182-191.
- doi: 10.5213/inj.2346148.074
Purpose: We evaluated the therapeutic effects on overactive bladder (OAB) symptoms and sexual function of behavioral therapy with or without mirabegron in sexually active male patients with OAB. Mirabegron, a... -
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- Long-term Combination Therapy With α-Blockers and 5α-Reductase Inhibitors in Benign Prostatic Hyperplasia: Patient Adherence and Causes of Withdrawal From Medication
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Ong HL, Liao CH, Kuo HC
- KMID: 2365702
- Int Neurourol J.
- 2016 Dec;20(4):356-362.
- doi: 10.5213/inj.1632526.263
PURPOSE: To investigate long-term therapeutic effects and patient adherence to a combination therapy of a 5α-reductase inhibitor and an α-blocker and to identify causes of withdrawal from medication in patients... -
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- Mercury Promotes Catecholamines Which Potentiate Mercurial Autoimmunity and Vasodilation: Implications for Inositol 1,4,5-Triphosphate 3-Kinase C Susceptibility in Kawasaki Syndrome
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Yeter D, Deth R, Kuo HC
- KMID: 2224813
- Korean Circ J.
- 2013 Sep;43(9):581-591.
- doi: 10.4070/kcj.2013.43.9.581
Previously, we reviewed biological evidence that mercury could induce autoimmunity and coronary arterial wall relaxation as observed in Kawasaki syndrome (KS) through its effects on calcium signaling, and that inositol... -
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