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Effective Titration of Risperidone in Patients with Schizophrenia: Open Multicenter Randomized Comparative 8 Weeks Study

Lee HS, Kim CH, Kim YH, Yoon DJ, Lee MS, Suh HS, Koo MS, The Multicenter Clinical Trial Group

  • KMID: 2037063
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):276-288.
OBJECTIVE: Subsequent clinical experiences in risperidone treatment indicated that the initially recommended dose schedule resulted in too rapid increment of doses to the maintenance dose. The goal of this study...
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Effect of Mirtazapine on Memory Function of Patients with Posttraumatic Stress Disorder

Jeon YJ, Chung MY, Chung HG

  • KMID: 2037060
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):254-261.
OBJECTIVE: This study was conducted to evaluate efficacy on symptoms and memory function of mirtazapine treatment of posttraumatic stress disorder. METHODS: Thirty Vietnam veterans were collected for this study, among whom...
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Comparison of the Dopamine Response in the Rat Prefrontal Cortex Induced by Irregular and Regular Electrical Stimuli

Chung YC, Moon SG, Eun HB, Hwang IK, Lim CW, Han JH

  • KMID: 2037058
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):239-245.
OBJECTIVE: In general, it is known that repetitive regular stimuli induce tolerance and repetitive irregular stimuli induce sensitization. We sought to determine the dopamine response in the rat prefrontal cortex...
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Effects of Maternal Separation and Fluoxetine Treatment on the Expressions of Nitric Oxide Synthases in Hypothalamus of Rat Brain

Cho GJ, Kim SA, Lee HJ, Chung JH, Kim JW

  • KMID: 2037061
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):262-268.
OBJECTIVE: This study was aimed to clarify the effects of maternal separation and fluoxetine treatment on the expression of nitric oxide synthase (NOS) in rat hypothalamus. METHODS: Rat pups were separated...
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Tretment Effect of Bromocriptine on Antipsychotics-induced Amenorrhea

Park CH, Jang HJ, Choi HS, Han OS, Kim CY

  • KMID: 2037057
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):233-238.
Amenorrhea is one of the well-known side effects of antipsychotics in women. It is associated with hyperprolactinemia induced by dopamine blocking effect of antipsychotics. Administration of bromocriptine which belongs to...
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Combination of Topiramate in Acute Mania

Yoon BH, Bae SO, Yoon JS, Lee KL, Choi Y

  • KMID: 2037059
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):246-253.
OBJECTIVE: The rapid therapeutic action of mood stabilizers is critical to the initial management of acute mania, because it enables to minimize the psychological sequelae of the patients commonly occurred...
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The Effect of Immobilization Stress and Corticosterone on Haloperidol-induced c-fos Expression in Rat Brain

Yoon JH, Kim KS, Lee KU, Lew TY

  • KMID: 2037062
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):269-275.
OBJECTIVE: Immediate early gene (IEG), c-fos is known to encode a 62 kDa nuclear protein (Fos) which has a critical role in the stimulus response process of many cells. c-fos...
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PANSS and Cognition Change in D-Cycloserine Compination Treatment of Schizophrenia

Yoon BM, Lee SG, Joe SH, Jeong IK, Kim SH

  • KMID: 2037064
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):289-296.
OBJECTIVE: Recently, there are many reports that glutamate receptors have close relationships with a pathophysiology of schizophrenia. The purpose of this study was to assess the effects of D-cycloserine, which...
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