- General Perspectives for Molecular Nuclear Imaging
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Chung JK
- KMID: 2078801
- Korean J Nucl Med.
- 2004 Apr;38(2):111-114.
Molecular imaging provides a visualization of normal as well as abnormal cellular processes at a molecular or genetic level rather than at a anatomical level. Conventional medical imaging methods utilize... -
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- Nuclear Medicine Imaging Instrumentations for Molecular Imaging
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Chung YH, Song TY, Choi Y
- KMID: 2078804
- Korean J Nucl Med.
- 2004 Apr;38(2):131-139.
Small animal models are extensively utilized in the study of biomedical sciences. Current animal experiments and analysis are largely restricted to in vitro measurements and need to sacrifice animals to... -
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- Ethical and Regulatory Problems of Molecular Imaging
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Jeong JM
- KMID: 2078805
- Korean J Nucl Med.
- 2004 Apr;38(2):140-142.
As a molecular imaging is the most up-to-date technology in Nuclear Medicine, it has complicate ethical and regulatory problems. For animal experiment, we have to follow institutional animal care committee.... -
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- Molecular Nuclear Cardiac Imaging
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Lee DS, Paeng JC
- KMID: 2078810
- Korean J Nucl Med.
- 2004 Apr;38(2):175-179.
Molecular nuclear cardiac imaging has included Tc-99m Annexin imaging to visualize myocardial apoptosis, but is now usually associated with gene therapy and cell-based therapy. Cardiac gene therapy was not successful... -
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- Radiolabeling Methods Used for Preparation of Molecular Probes
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Choe YS
- KMID: 2078803
- Korean J Nucl Med.
- 2004 Apr;38(2):121-130.
Molecular imaging visualizes cellular processes at a molecular or genetic level in living subjects, and diverse molecular probes are used for this purpose. Radiolabeling methods as well as radioisotopes are... -
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- PET-Based Molecular Nuclear Neuro-Imaging
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Kim JH
- KMID: 2078808
- Korean J Nucl Med.
- 2004 Apr;38(2):161-170.
Molecular Nuclear Neuro - Imaging in "CNS" drug discovery and development can be divided into four categories that are clearly inter-related. (1) Neuroreceptor mapping to examine the involvement of specific... -
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- In Vivo Nuclear Imaging of Apoptosis
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Lee TS, Cheon GJ
- KMID: 2078812
- Korean J Nucl Med.
- 2004 Apr;38(2):190-197.
Apoptosis plays a role in the pathophysiology of many kinds of diseases and in the response of treatment. Compared to the necrosis, the apoptosis is a genetically controlled and energy-dependent... -
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- Radionuclide Reporter Gene Imaging
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Min JJ
- KMID: 2078806
- Korean J Nucl Med.
- 2004 Apr;38(2):143-151.
Recent progress in the development of non-invasive imaging technologies continues to strengthen the role of molecular imaging biological research. These tools have been validated recently in variety of research models,... -
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- Molecular Nuclear Imaging of Angiogenesis
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Lee KH
- KMID: 2078809
- Korean J Nucl Med.
- 2004 Apr;38(2):171-174.
Angiogenesis, the formation of new capillaries from existing vessels, increases oxygenation and nutrient supply to ischemic tissue and allows tumor growth and metastasis. As such, angiogenisis targeting provides a novel... -
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- Nuclear Imaging of Cellular Proliferation
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Yeo JS
- KMID: 2078813
- Korean J Nucl Med.
- 2004 Apr;38(2):198-204.
Tumor cell proliferation is considered to be a useful prognostic indicator of tumor aggressiveness and tumor response to therapy, but in vitro measurement of individual proliferation is complex and tedious... -
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- Introduction To Basic Molecular Biologic Techniques For Molecular Imaging Researches
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Kang JH
- KMID: 2078802
- Korean J Nucl Med.
- 2004 Apr;38(2):115-120.
Molecular imaging is a rapidly growing field due to the advances in molecular biology and imaging technologies. With the introduction of imaging reporter genes into the cell, diverse cellular processes... -
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- Detection of Multidrug Resistance Using Molecular Nuclear Technique
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Lee J, Ahn BC
- KMID: 2078811
- Korean J Nucl Med.
- 2004 Apr;38(2):180-189.
Although the outcome of cancer patients after cytotoxic chemotherapy is related diverse mechanisms, multidrug resistance (MDR) for chemotherapeutic drugs due to cellular P-glycoprotein (Pgp) or multidrug-resistance associated protein (MRP) is... -
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- MR Contrast Agents and Molecular Imaging
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Moon WK
- KMID: 2078814
- Korean J Nucl Med.
- 2004 Apr;38(2):205-208.
The two major classes of magnetic resonance (MR) contrast agents are paramagnetic contrast agents, usually based on chelates of gadolinium generating T1 positive signal enhancement, and super-paramagnetic contrast agents that... -
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- Molecular Imaging Using Sodium Iodide Symporter (NIS)
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Cho JY
- KMID: 2078807
- Korean J Nucl Med.
- 2004 Apr;38(2):152-160.
Radioiodide uptake in thyroid follicular epithelial cells, mediated by a plasma membrane transporter, sodium iodide symporter (NIS), provides a first step mechanism for thyroid cancer detection by radioiodide injection and... -
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