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Role of p11 (S100A10) in Depression and Antidepressant Effects

Park SW, Seo MK, Lee JG, Kim YH

p11 protein (S100A10) is downregulated in depressive-like states of human and rodent. Antidepressant drug treatment increases p11 levels in rodent models. We reviewed studies demonstrating that p11 levels are regulated...
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Novel Pharmacological Treatment for Depression

Jeong HJ, Moon E

Development of various antidepressants such as monoamine oxidase inhibitors, tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and noradrenergic and specific serotonergic antidepressant has led to a tremendous...
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Neuroinflammation and Psychiatric Illness

Song HR, Lee HY, Shim SH, Kwon YJ

Neuroinflammation is one of important allostatic loads contributory to the various psychiatric illness. It is mediated mainly by glial cells, which produce both proinflammatory and antiinflammatory cytokines, and the balance...
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Mammalian Target of Rapamycin Signaling Pathways and Depression

Lee JG, Seo MK, Park SW, Kim YH

Depression is a complicated psychiatric illness with severe consequences. Despite recent advanced achievements of molecular neurobiology, pathophysiology of depression has not been well elucidated. Among new findings of pathophysiology of...
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Reliability and Validity of the Korean Version of the Post-Traumatic Stress Disorder Checklist in Public Firefighters and Rescue Workers

Park S, Jeong HS, Im JJ, Jeon Y, Ma J, Choi Y, Ban S, Kim S, Yu S, Lee S, Jeon S, Kang I, Lee B, Lee S, Son J, Lim JH, Yoon S, Kim EJ, Kim JE, Lyoo IK

OBJECTIVES: Firefighters and rescue workers are likely to be exposed to a variety of traumatic events; as such, they are vulnerable to the risk of post-traumatic stress disorder (PTSD). The...
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