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Epigenetics and Psychiatric Disorders

Oh D, Yang BH, Lee YS

  • KMID: 2299915
  • Korean J Biol Psychiatry.
  • 2008 Nov;15(4):243-253.
In the post-genomic era, the mechanisms controlling activation of genes are thought to be more important. Gene-environment interactions are crucial in both development and treatment of psychiatric disorders as they...
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Depression and Coronary Artery Disease(I): Pathophysiologic Mechanisms

Bae KY, Kim JM, Yoon JS

  • KMID: 2299918
  • Korean J Biol Psychiatry.
  • 2008 Nov;15(4):275-287.
Depression and coronary artery disease are both highly prevalent diseases. Many previous studies suggest that depression is a common comorbid condition in patients with coronary artery disease and has a...
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Depression in Patients with End-Stage Renal Disease

Kim SY, Kim JM, Yoon JS

  • KMID: 2299917
  • Korean J Biol Psychiatry.
  • 2008 Nov;15(4):265-274.
Depression is common in patients with end-stage renal disease(ESRD) and has a negative effect on the quality of life, functional ability, and mortality of the patients, with a prevalence rate...
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Neural Substrates of Fear Based on Animal and Human Studies

Baek K, Jeong J, Park MS, Chae JH

  • KMID: 2299916
  • Korean J Biol Psychiatry.
  • 2008 Nov;15(4):254-264.
OBJECTIVES: The neural substrate of fear is thought to be highly conserved among species including human. The purpose of this review was to address the neural substrates of fear based...
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Association of the 5-HT5A Receptor Gene Polymorphisms and Citalopram Response in Korean Patients with Major Depressive Disorder

Shim JH, Paik JW, Oh JW, Kang RH, Lee HY, Lee MS

  • KMID: 2299921
  • Korean J Biol Psychiatry.
  • 2008 Nov;15(4):303-309.
OBJECTIVES: Some reports have suggested that 5-HT5A polymorphism allelic association was associated with depression, however, there has been no report about relationship between the 5-HT5A gene and antidepressant response. We...
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Opinion of Experts about Psychiatric Evaluation after Trauma in Korea

Lee BC, Ryu SG, Jung HY

  • KMID: 2299922
  • Korean J Biol Psychiatry.
  • 2008 Nov;15(4):310-315.
OBJECTIVES: The evaluation of disability after trauma in psychiatry is relatively subjective compared with other departments. A consensus among evaluators could improve reliability of evaluations. We compared disability rate of...
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The Effect of Schizotypal Personality Trait on the Ability of Facial Affect Identification in Healthy Person

Yi HL, Kim SY, Choo JS, Lee KU, Chae JH, Park YM, Kim H, Lee KJ, Chung YC, Lee SH

  • KMID: 2299920
  • Korean J Biol Psychiatry.
  • 2008 Nov;15(4):297-302.
OBJECTIVES: The purpose of this study is to investigate whether the ability of facial affect perception is associated with schizotypal personality traits in healthy normal controls. METHODS: 241 normal subjects were...
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No Association between Val108/158Met Polymorphism on Catechol-O-Methyl Transferase(COMT) Gene and Smooth Pursuit Eye Movement(SPEM) Abnormality in Korean Schizophrenia Patients

Jang HJ, Moon HI, Lee YJ, Kim IY, Lee IS, Seo HG, Kim KH, Shin TM, Park BL, Shin HD, Han SH, Han SW, Woo SI

  • KMID: 2299919
  • Korean J Biol Psychiatry.
  • 2008 Nov;15(4):288-296.
OBJECTIVES: We investigated the association of Val108/158Met polymorphism on catechol-O-methyl transferase(COMT) gene with smooth pursuit eye movement(SPEM) abnormality in Korean schizophrenia patients. METHODS: We measured SPEM in 217 Korean schizophrenia patients(male...
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