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Can We Predict Treatment Response in Major Depression?

Ko YH, Kim YK

  • KMID: 2248975
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):77-87.
Due to the high population prevalence of major depression and the strong emphasis on pharmacotherapy for this disorder, antidepressants are among the most frequently prescribed pharmacological agents. But the clinicians...
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Serum Brain-Derived Neurotrophic Factor in Schizophrenia

Kim SY, Min KJ, Kee BS, Park DB, Kim JH

  • KMID: 2248978
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):104-109.
OBJECTIVES: Abnormalities in neurotrophic factors that regulate neuronal development and synaptic plasticity are often implicated as some causes of schizophrenia. In previous studies, researchers reported that brain and serum BDNF...
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A Family-Based and Case-Control Association Study of the Serotonin 1B Receptor Gene Polymorphism in Korean Attention Deficit Hyperactivity Disorder

Park TW, Kim BN, Im MH, Yoo HJ, Kang D, Chung YC

  • KMID: 2248983
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):146-154.
OBJECTIVE: Attention deficit hyperactivity disorder(ADHD) is the most common childhood psychiatric disorder, affecting 3-5% of school-aged children. Although the biological basis of ADHD is unknown, family studies provide strong evidence...
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Polymorphism of Dopamine Transporter Gene(DAT1) in Korean Social Phobia Patients: Preliminary Study

Oh KS, Yoon HK, Lee MS

  • KMID: 2248985
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):165-172.
OBJECTIVE: Although polymorphism of dopamine transporter gene(DAT1) has been considered to be implicated in the pathogenesis of social phobia, previous investigations have been inconsistent and controversial. The authors investigated the...
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Association between Serotonin 2A(T102C) and 1B(G861C) Receptor Gene Polymorphism and Suicidal Attempt with Drug Intoxication in Korean Populations

Kim DH, Kwon YJ, Kim JW, Shim SH, Jung HY

  • KMID: 2248979
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):110-116.
OBJECTIVES: Recently, polymorphisms of several serotonin genes have been suggested to be associated with suicide, but the results are still unclear. We examined whether the T102C polymorphisms of the serotonin...
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An Association Study of the 5-HTTLPR and COMT Genes Polymorphisms and Personality Traits

Ha JH, Ham BJ, Ryu SG, Hwang TY, Lee JG, Lee YS, Lee JS, Kang DY, Choi IG, Lee MS

  • KMID: 2248976
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):88-93.
BACKGROUND: Serotonin transporter gene-linked polymorphism region(5-HTTLPR) and catechol-O-methyltransferase(COMT) genes are thought to be important factors in some personality traits and the etiology of anxiety disorder. The goal of this study...
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The Influences of Risperidone and Clozapine on Body Weight and Glucose Level in Patients with Chronic Schizophrenia: Comparison Study with Haloperidol

Nam CW, Yang BH, Lee JN

  • KMID: 2248981
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):127-135.
OBJECT: The goal of this study was to examine the changes in body weight and glucose levels of the patients treated with risperidone, clozapine or haloperidol in order to compare...
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Comparison of Serum Homocysteine, Folate and Vitamin B12 Level in Korean Schizophrenics

Kim TH, Lee YS, Song SY, Min KJ, Kee BS, Na C, Chae SL

  • KMID: 2248977
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):94-103.
OBJECTIVE: There have been a kind of transmethylation theory that high homocysteine serum concentration affects schizophrenia by neurotoxic mechanism and clinical reports that some schizophrenic patients with high homocysteine were...
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Changes in the Regional Cerebral Perfusion after Eye Movement Desensitization and Reprocessing: A SPECT Study of Two Cases

Oh DH, Choi J

  • KMID: 2248986
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):173-180.
Over the last decade, EMDR(Eye Movement Desensitization and Reprocessing) has emerged as a promising new treatment for trauma and other anxiety-based disorders. However, neurobiological mechanism of EMDR has not been...
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No Association between Genetic Polymorphism of Tryptophan Hydroxylase A218C and Serotonin Transporter Linked Polymorphic Region and Panic Disorder

Choi YH, Woo JM, Park HK, Yoon KS, Cho DY, Lee MS

  • KMID: 2248982
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):136-145.
OBJECTIVES: Genetic variations of the tryptophan hydroxylase(TPH) gene and the serotonin transporter linked polymorphic region(5-HTTLPR) polymorphism have been associated with its functional capacity. The authors investigated whether the allelic constitution...
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The Relationship between Neurocognitive Functioning and Emotional Recognition in Chronic Schizophrenic Patients

Hwang HL, Hwang TY, Lee WK, Han ES

  • KMID: 2248984
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):155-164.
OBJECTIVE: The present study examined the association between basic neurocognitive functions and emotional recognition in chronic schizophrenia. Furthermore, to Investigate cognitive variable related to emotion recognition in Schizophrenia. METHODS: Forty eight...
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Correlations of Abnormal Involuntary Movements with Blood Glucose, Lipid Levels in Chronic Schizophrenics

Kim HS, Kim EJ, Lee JH, Ji SH

  • KMID: 2248980
  • Korean J Biol Psychiatry.
  • 2004 Nov;11(2):117-126.
OBJECTS: It has been reported that the incidence of tardive dyskinesia(TD), the remarkable abnormal involuntary movement, was higher in the schizophrenics with high blood sugar levels and that TD had...
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