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Peanut Sprout Extracts Cultivated with Fermented Sawdust Medium Inhibits Benign Prostatic Hyperplasia In Vitro and In Vivo

Song JH, Hwang B, Chung HJ, Moon B, Kim JW, Ko K, Kim BW, Kim WR, Kim WJ, Myung SC, Moon SK

Purpose: In this study, we tested whether the resveratrol-enriched peanut sprout extracts cultivated with fermented sawdust medium (PSEFS) could suppress benign prostatic hyperplasia (BPH) in vitro and in vivo. Materials and...
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Alteration of Genomic Imprinting Status of Human Parthenogenetic Induced Pluripotent Stem Cells during Neural Lineage Differentiation

Lee HJ, Choi NY, Lee SW, Lee Y, Ko K, Kim GJ, Hwang HS, Ko K

BACKGROUND AND OBJECTIVES: Genomic imprinting modulates growth and development in mammals and is associated with genetic disorders. Although uniparental embryonic stem cells have been used to study genomic imprinting, there...
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Reprogramming of Cancer Cells into Induced Pluripotent Stem Cells Questioned

Bang JS, Choi NY, Lee M, Ko K, Park YS, Ko K

BACKGROUND AND OBJECTIVES: Several recent studies have claimed that cancer cells can be reprogrammed into induced pluripotent stem cells (iPSCs). However, in most cases, cancer cells seem to be resistant...
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Development of Protocol for Korean Lung Cancer Screening Project (K-LUCAS) to Evaluate Effectiveness and Feasibility to Implement National Cancer Screening Program

Lee J, Lim J, Kim Y, Kim HY, Goo JM, Lee CT, Jang SH, Lee WC, Lee CW, An JY, Ko KD, Lee MK, Choi KS, Park B, Lee DH

PURPOSE: To reduce lung cancer mortality, lung cancer screening was recommended using low-dose computed tomography (LDCT) to high-risk population. A protocol for multicenter lung cancer screening pilot project was developed...
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Simultaneous Determination of Four Compounds from Artemisia capillaris using High Performance Liquid Chromatography-Ultraviolet Detector (HPLC-UVD) and Their Quantitative Study in Artemisia Genus

Ko K, Hong IK, Cho HJ, Kim YH, Yang H

Artemisia capillaris Thunb. (Compositae) is a native herb of East Asian countries and has used for the treatment of jaundice, high liver fever, and digestive diseases for a long time,...
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A Possible Case of Statin-Induced Ichthyosis in an Elderly Woman

Ko KD, Kim KK, Baek JO, Suh HS, Hwang IC

Ichthyosis is a heterogeneous group of hereditary or acquired skin disorders, characterized by increased stratum corneum production. Several systemic diseases and many drugs can occasionally cause acquired ichthyosis. We report...
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Production of Recombinant Anti-Cancer Vaccines in Plants

Lee JH, Ko K

Plant expression systems have been developed to produce anti-cancer vaccines. Plants have several advantages as bioreactors for the production of subunit vaccines: they are considered safe, and may be used...
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Does Weight Gain Associated with Thiazolidinedione Use Negatively Affect Cardiometabolic Health?

Ko KD, Kim KK, Lee KR

Thiazolidinediones (TZDs) are oral anti-diabetic drugs that are peroxisome proliferator-activated receptor gamma (PPARγ) agonists and act as insulin sensitizers. The clinical efficacy and durability of the currently available TZDs in...
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Link between Short Sleep Duration and Hypertension

Ko KD

No abstract available.
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Evaluation of Serum Cotinine Cut-Off to Distinguish Smokers From Nonsmokers in the Korean Population

Ko K, Kwon MJ, Yang SH, Moon CJ, Lee EH, Woo HY, Park H

BACKGROUND: Cotinine has been widely used as an objective marker to identify current smokers. We conducted this study to address the absence of Korean studies investigating the efficacy of immunoassays...
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Identification of Mixed Lineage Leukemia Gene (MLL)/MLLT10 Fusion Transcripts by Reverse Transcription-PCR and Sequencing in a Case of AML With a FISH-Negative Cryptic MLL Rearrangement

Ko K, Kwon MJ, Woo HY, Park H, Park CH, Lee ST, Kim SH

No abstract available.
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Evaluation of Analytical Performance of the Cobas 8000 Analyzer Series Module e602

Ko K, Kwon MJ, Woo HY, Park H

BACKGROUND: The e602, a module of the recently released cobas 8000 modular analyzer series, is an automated system for immunoassays. In this study, we evaluated its analytical performance using 17...
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Effective dose of dexmedetomidine to induce adequate sedation in elderly patients under spinal anesthesia

Ko KH, Jun IJ, Lee S, Lim Y, Yoo B, Kim KM

BACKGROUND: During sedation with dexmedetomidine, a dose adjustment may be needed based on the invasiveness of the procedure, the patient's general condition, and their age. We aim here to determine...
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A Case of Amyloid Goiter Masquerading as Graves' Disease

Kim HB, Lee SH, Ko KB, Cho JH

Amyloidosis is an abnormal extracellular deposit of amyloid in various organs of the body. Amyloid goiter, defined by a clinically detectable thyroid enlargement due to amyloid deposition, is a rare...
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Subclinical Thyroid Dysfunction in the Elderly

Ko KD

Subclinical thyroid dysfunction, including both subclinical hyperthyroidism and subclinical hypothyroidism is biochemically defined as an abnormal thyroid-stimulating hormone (TSH) level and thyroid hormone level within its reference range. The prevalence...
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Association of Arterial Stiffness and Osteoporosis in Healthy Men Undergoing Screening Medical Examination

Kim NL, Jang HM, Kim SK, Ko KD, Hwang IC, Suh HS

BACKGROUND: Association of arterial stiffness and osteoporosis has been previously reported in women. However, this association is still controversial for men. Therefore, we investigated correlation of arterial stiffness and osteoporosis...
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Clinical Features of Non-alcoholic Fatty Liver Disease in Cryptogenic Hepatocellular Carcinoma

Rim MY, Kwon OS, Ha M, Kim JS, Ko KI, Kim DK, Jang PK, Han JY, Park PH, Jung YK, Choi DJ, Kim YS, Kim JH

BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) may be one of the important causes of cryptogenic hepatocellular carcinoma (HCC). The aim of this study was to evaluate whether patients with cryptogenic...
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Acute Megakaryoblastic Leukemia with CD41a-/CD61-/CD42a+ Blasts in an Infant with Down Syndrome

Ko K, Kwon MJ, Jang MA, Lee ST, Woo HY, Park H, Kim SH

  • KMID: 2312251
  • Lab Med Online.
  • 2014 Apr;4(2):112-115.
Infants with Down syndrome have increased incidences of transient abnormal myelopoiesis (TAM) and acute leukemia, which are usually associated with acute megakaryoblastic leukemia (AMKL). A 5-day-old girl with Down syndrome...
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Effect of Peritoneal Dialysis Modality on the 1-Year Rate of Decline of Residual Renal Function

Kim CH, Oh HJ, Lee MJ, Kwon YE, Kim YL, Nam KH, Park KS, An SY, Ko KI, Koo HM, Doh FM, Han SH, Yoo TH, Kim BS, Kang SW, Choi KH

PURPOSE: The effect of different peritoneal dialysis (PD) modalities on the decline in residual renal function (RRF) is unclear due to inconsistencies among studies. In particular, the effect of automated...
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Membranous glomerulonephritis in a patient with myelodysplastic syndrome-refractory cytopenia with multilineage dysplasia

Ko KI, Lee MJ, Doh FM, Koo HM, Kim CH, Shin DH, Oh HJ, Han SH, Kang SW, Choi KH, Yoo TH

  • KMID: 2224308
  • Kidney Res Clin Pract.
  • 2013 Sep;32(3):134-137.
A 74-year-old woman presented with edema in the lower extremities. Laboratory tests revealed anemia, thrombocytopenia, hypoalbuminemia, hypercholesterolemia, and nephrotic-range proteinuria. Myelodysplastic syndrome-refractory cytopenia with multilineage dysplasia (MDS-RCMD) was confirmed by...
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