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An elderly woman with severe enteritis mimicking infectious enteritis

Nagashima K, Kato T, Kimura T, Kishi K, Baba U

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The impacts of computer adaptive testing from a variety of perspectives

Kimura T

Computer adaptive testing (CAT) is a kind of tailored testing, in that it is a form of computer-based testing that is adaptive to each test-taker's ability level. In this review,...
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Complex Epidemiology of Prostate Cancer in Asian Countries

The incidence of prostate cancer (PCa) has increased worldwide in recent years along with the recommendation for prostate-specific antigen testing, and mortality has been declining owing to advances in fragmented...
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Endoscopic Management of Nonvariceal Upper Gastrointestinal Bleeding: State of the Art

Muguruma N, Kitamura S, Kimura T, Miyamoto H, Takayama T

Nonvariceal upper gastrointestinal (GI) bleeding is one of the most common reasons for hospitalization and a major cause of morbidity and mortality worldwide. Recently developed endoscopic devices and supporting apparatuses...
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Sodium-glucose Co-transporters-2 Inhibitors and Heart Failure: State of the Art Review and Future Potentials

Kato ET, Kimura T

Heart failure (HF) and type 2 diabetes mellitus (T2DM) are progressive chronic diseases that increase the risk of mortality and have worse outcomes when they coexist. There has been a...
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Postoperative Meningitis in Patients with Cervical Cord Tumor: A Case Report

Kawaguchi , Seki S, Yasuda T, Nakamura Y, Nakano M, Kimura T

Postoperative meningitis after spinal surgery is a rare complication that can result in a life-threatening condition. Linezolid (LZD) is an oxazolidinone which has been approved in Japan for infections caused...
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Full-Endoscopic Transcervical Ventral Decompression for Pathologies of Craniovertebral Junction: Case Series

Ohara Y, Nakajima Y, Kimura T, Kikuchi N, Sagiuchi T

Odontoidectomy is very effective for the decompression of the ventral craniovertebral junction (CVJ). Various approaches are available for the direct ventral decompression of the CVJ. Because there are many disadvantages...
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Carboplatin and paclitaxel as an initial treatment in patients with stage IVb cervical cancer: a report of 7 cases and a review of the literature

Mabuchi S, Morishige , Enomoto T, Kimura T

OBJECTIVE: The aim of this study is to evaluate the efficacy of carboplatin-paclitaxel (TC) as an initial treatment in patients with the International Federation of Gynecology and Obstetrics (FIGO) stage...
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Clear cell carcinoma of the ovary: molecular insights and future therapeutic perspectives

Mabuchi S, Sugiyama T, Kimura T

Clear cell carcinoma (CCC) of the ovary is known to show poorer sensitivity to chemotherapeutic agents and to be associated with a worse prognosis than the more common serous adenocarcinoma...
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Circumferential Spinal Cord Decompression through a Single Posterior Approach with Microendoscopy for Thoracic and Thoracolumbar Ossification of the Posterior Longitudinal Ligament

Seki S, Mine H, Kawaguchi , Makino H, Kimura T

Thoracic and thoracolumbar ossification of the posterior longitudinal ligament (OPLL) can be difficult to treat due to the anatomical position. The purpose of this study was to report the significance...
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Placenta percreta with a vaginal fistula after successful management by uterine transverse fundal incision and subsequent cesarean hysterectomy

Matsuzaki , Matsuzaki , Ueda Y, Egawa-Takata T, Mimura K, Kanagawa T, Morii E, Kimura T

Placenta previa presents a highest risk to pregnancy, and placenta accreta is the most serious. Placenta accreta requires cesarean delivery and often results in massive obstetric hemorrhage and higher maternal...
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Lumbar Spinal Stenosis Due to a Large Calcified Mass in the Ligamentum Flavum

Seki S, Kawaguchi , Ishihara H, Oya T, Kimura T

We describe a rare case of lumbar spinal stenosis due to a large calcified mass in the ligamentum flavum. This patient presented with a 12-month history of severe right leg...
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Twin Rectal Tonsils Mimicking Carcinoid or Mucosa-Associated Lymphoid Tissue Lymphoma

Takehara M, Muguruma N, Kitamura S, Kimura T, Okamoto K, Miyamoto H, Bando Y, Takayama T

The rectal tonsil is a rare polypoid lesion exclusively found in the rectum and is considered a reactive proliferation of the lymphoid tissue. Although this lesion is benign, we recommend...
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Compression Myelopathy due to Proliferative Changes around C2 Pars Defects without Instability

Kimura T, Sakai T, Tezuka F, Abe M, Yamashita , Takata Y, Higashino , Sairyo K

We report a case with compression myelopathy due to proliferative changes around the C2 pars defects without instability. A 69-year-old man presented with progressive clumsy hands and spastic gait. Plain...
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Multi-focal Myxopapillary Ependymoma in the Lumbar and Sacral Regions Requiring Cranio-spinal Radiation Therapy: A Case Report

Andoh H, Kawaguchi , Seki S, Asanuma Y, Fukuoka J, Ishizawa S, Kimura T

Ependymomas are uncommon tumors that arise in the brain, spinal cord or cauda equina. Myxopapillary ependymomas is located exclusively in the conus medullaris or cauda equina, or film terminale region....
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Influence of Psychotropic Pro Re Nata Drug Use on Outcomes in Hospitalized Patients with Schizophrenia

Kyou Y, Oishi S, Takizawa T, Yoshimura Y, Hashimoto I, Suzuki R, Demizu R, Ono T, Noguchi Y, Kimura T, Inada K, Miyaoka H

Objective: In the treatment of patients with schizophrenia, pro re nata (PRN) drugs are commonly prescribed for medical indications such as agitation, acute psychiatric symptoms, insomnia, and anxiety. However, high-quality...
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Trichoblastomas derived from the facial skin with tactile hair in aged house musk shrews (Suncus murinus)

Kimura T

Background: Benign hair follicle tumors are relatively rare cutaneous neoplasms arising from hair follicle differentiation. These tumors are slow-growing solitary papules or nodules in the head, face or neck. The...
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Two Manganese Peroxidases and a Laccase of Trametes polyzona KU-RNW027 with Novel Properties for Dye and Pharmaceutical Product Degradation in Redox Mediator-Free System

Lueangjaroenkit P, Teerapatsakul C, Sakka K, Sakka M, Kimura T, Kunitake E, Chitradon

Two manganese peroxidases (MnPs), MnP1 and MnP2, and a laccase, Lac1, were purified from Trametes polyzona KU-RNW027. Both MnPs showed high stability in organic solvents which triggered their activities. Metal...
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Portal bifurcation reconstruction using own hepatic vein grafts due to portal vein anomaly of the living donor for the patient with portal vein thrombosis

Umemura A, Nitta H, Takahara T, Hasegawa Y, Katagiri H, Kanno S, Kobayashi M, Ando T, Kimura T, Sasaki A

A 57-year-old Japanese female was considered for living donor liver transplantation (LDLT) due to end-stage liver cirrhosis caused by primary biliary cholangitis with portal vein thrombosis (PVT) formation. A 26-year-old...
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Prolyl Isomerase Pin1 Expression in the Spinal Motor Neurons of Patients With Sporadic Amyotrophic Lateral Sclerosis

Kato H, Naito M, Tomoko T, Hideyama T, Yasuhiro Y, Kimura T, Kwak S, Hitoshi H

Background and Purpose Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease. Selective deficiency of edited adenosine deaminase acting on RNA 2 (ADAR2), a key molecule in the acquisition...
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