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Necrotizing Fasciitis in a 7-day-old Term Healthy Neonate

Koo SH, Chung ML, Park KB

Necrotizing fasciitis is a rare, but life-threatening infection. Prompt diagnosis and early aggressive intervention is required for survival. However, there has been frequently occurred in delays of diagnosis and treatment...
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Disorders in Hemostasis

Sung TJ

Neonatal bleeding is a common problem encountered in nursery rooms or neonatal intensive care units, especially among premature infants. Furthermore, owing to recent remarkable improvement of neonatology, survival rates of...
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Anticoagulation Therapy, Thrombolytic Therapy, and Use of Blood Products in Neonates

Choi CW

Neonatal coagulation disorders and thromboembolism require timely management. Failure to treat these conditions at the appropriate time may lead to death or the development of significant long-term sequelae. However, most...
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Neonatal Thromboembolic Disorders

Kim DH

The etiology of thrombosis is multifactorial and involves the interaction of inherited and acquired risk factors. Many neonatal thromboembolic disorders are iatrogenic and their incidence is likely to increase as...
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The First Neonatal Case of Neonatal Argininosuccinic Aciduria in Korea

Hwang IO, Lee ES

Argininosuccinic aciduria (ASAuria) is a rare autosomal recessive urea cycle disorder. Neonatal presentation of ASAuria is the most common form. It is characterized by lethargy, feeding intolerance, decreased consciousness, and...
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Longitudinal Study of Iron Concentration in Korean Preterm Human Milk

Lim G, Koo MS, Kim EA, Min WK, Yoon SC

PURPOSE: The unique nutrient requirements of premature infants necessitate knowledge of the composition of human milk produced by mothers of such infants. We investigated longitudinal changes in iron concentration of...
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Adverse Effects of Chloral Hydrate in Neonates: Frequency and Related Factors

Lee J, Youn YA, Kim SJ, Lee HS, Kim SY, Sung IK, Chun CS

PURPOSE: Chloral hydrate is a common drug frequently used for procedural sedation. But data on chloral hydrate use in the newborns are limited. This study examined the frequency of adverse...
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Introduction to Coagulation System

Lyu CJ

Coagulation involves the regulated sequence of proteolytic activation of a series of proteins to achieve appropriate and timely hemostasis in an injured vessel. In the non-pathological state, the inciting event...
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Two Cases of Tension Pneumopericardium in Mechanically Ventilated Preterm Infants

Maeng SH, Seo HJ, Shin J, Jung J, Kim JK, Yoo HS, Ahn SY, Kim ES, Chang YS, Park WS

Pneumopericardium is a rare form of neonatal air leakage. Tension pneumopericardium is much more infrequent, but can cause a cardiovascular deterioration with high mortality up to 80% and neurodevelopmental morbidity...
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Neonatal Coagulation Disorder: Diagnostic Approaches for Bleeding Neonates

Kim CS

All newborn infants with clinically significant bleeding should be evaluated for a hemostatic deficit. Medical history should include the following data: familial bleeding disorders, maternal illness and medication, age of...
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Two Cases of Dry Lung Syndrome

Song IG, Kim SY, Lee JY, Lee EH, Sohn JA, Choi EJ, Kim ES, Lee HJ, Lee JA, Choi CW, Kim EK, Kim HS, Kim BI, Choi JH

Preterm infants with oligohydramnios after preterm premature rupture of membranes can present with severe respiratory distress immediately after birth, and the most common cause is pulmonary hypoplasia. Unlike infants with...
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Hypernatremia and Intraventricular Hemorrhage in Very Low Birth Weight Infants (<1,250 g)

Lee SH, So CH, Keum SH, Yoo ST, Choi DY, Oh YK

PURPOSE: Hypernatremia most frequently occurs in the immature newborn and be severe in association with intraventricular hemorrhage (IVH). This study examined the frequency, onset and risk factors of hypernatremia, and...
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Oral Sildenafil in Persistent Pulmonary Hypertension of the Newborn

Son SB, Kim KA, Yun SY, Ko SY, Lee YK, Shin SM

PURPOSE: To evaluate the effect of oral sildenafil therapy in neonates with persistent pulmonary hypertension of the newborn (PPHN) METHODS: We conducted a retrospective review of 32 neonates > or =35...
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The Impact of Delayed Interval Delivery on Neonatal Mortality and Morbidity

Lee EH, Sohn JA, Lee JY, Choi EJ, Lee JA, Choi CW, Kim EK, Kim HS, Jun JK, Kim BI, Choi JH

PURPOSE: To evaluate the impact of delayed interval delivery on neonatal outcomes. METHODS: This was a retrospective study of infants who were born at Seoul National University Hospital by delayed interval...
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A Clinical Study of Congenital Intrahepatic Portosystemic Shunt Diagnosed in Neonatal Period

Kim JY, Kim KA, Lee YK, Ko SY, Shin SM, Han BH

PURPOSE: Congenital intrahepatic portosystemic shunts are rare disease and clinically asymptomatic shunts may be detected by chance on ultrasonogram before and after birth. We studied clinical course, treatment and prognosis...
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Cord Blood Adiponectin and Insulin-like Growth Factor-I in Term Neonates of Gestational Diabetes Mellitus Mothers: Relationship to Fetal Growth

Sohn JA, Park EA, Cho SJ, Kim YJ, Park H

PURPOSE: The purpose of this study was to evaluate the relationship between cord blood adiponectin and insulin-like growth factor (IGF)-I and their effect on fetal growth and insulin resistance in...
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Analysis of Maternal and Neonatal Transport by the 1339 Emergency Medical Information Center in Busan Area

Kim MJ, Lee MC, Yoo JH, Kim MJ

PURPOSE: In relation to perinatal healthcare, medical institutions and resources are limitative and also are in a state of flux due to the therapeutic specialty. We analyzed requests for interhospital...
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Regional Analysis on the Incidence of Preterm and Low Birth Weight Infant and the Current Situation on the Neonatal Intensive Care Units in Korea, 2009

Kang BH, Jung KA, Hahn WH, Shim KS, Chang JY, Bae CW

PURPOSE: Recently, the incidence of preterm and low birth weight infants (LBWI) is increasing, even though the birth rate is continuously low in Korea. Despite that change, there continues to...
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Effects of Early Parenteral Nutrition for Extremely Low Birth Weight Infants

Ahn SY, Shin JH, Shin JH, Sung SI, Jung JM, Kim JK, Chang YS, Park WS

PURPOSE: The object of this study was to evaluate the efficacy of early total parenteral nutrition with early amino acid in extremely low birth weight infant (ELBWI). METHODS: We retrospectively analyzed...
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Association between Tumor Necrosis Factor-alpha Gene Polymorphism and Bronchopulmonary Dysplasia in Preterm Infants

Jo HS, Chang YH, Kim HS, Kim BI, Choi JH

PURPOSE: Several factors including prolonged inflammatory response are thought to contribute to the pathogenesis of bronchopulmonary dysplasia (BPD). The clinical findings can be explained by an increased production of proinflammatory...
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