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The Significance of Bone Marrow Micrometastasis ( BMM ) in Breast Carcinoma

Kang SH, Lee SJ, Kim SW, Kwun KB

  • KMID: 2137114
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):76-85.
PURPOSE: This study was performed to determine the incidence of BMM and to correlate the presence of these micrometastases with prognosis and othet clinicopathologic features. Materials AND Methods: BMM was evaluated in 220 breast...
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Expression Pattern and Prognostic Correlation of BAG - 1 Protein in Breast Cancer

Cho SH, Lee DY, Kim BJ, Hong SH

  • KMID: 2137112
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):60-67.
PURPOSE: The objective of this study was to understand the expression of BAG-1 in the human breast cancer. MATERIALS AND METHODS: We studied its expression in one hundred and thirteen patients diagnosed...
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Accuraey of Cancer Death Certificates in KOREA: A comparison between diagnoses in the central cancer registry and certified underlying causes of death

Lee DH, Shin HR, Ahn DH, Chun BY, Kam S, Ahn YO

  • KMID: 2137128
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):210-219.
PURPOSE: We evaluated the accuracy of death certificates for persons who registered in the Central Cancer Registry in 1993 and died from 1993 to 1995. MATERIALS AND METHODS: The study consisted...
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Construction of MAGE - 3 Expressing Plasmid for Development of DNA Vaccine Encoding MAGE - 3 Cancer Antigen

Park JW, Lee MH, Yoon SJ, Baek WK, Suh SI, Suh MH, Lee KD, Yu TH

  • KMID: 2137126
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):191-199.
PURPOSE: The spectrum of melanoma antigen gene (MAGE)-expressing tumor is very wide and the gene of MAGE express antigens that are targets for specific recognition by cytotoxic T lymphocytes derived from tumor-bearing patients....
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Drug Resistance to 5 - Fluorouracil and Overexpression of Thymidylate Synthase mRNA in Human Gastrointestinal Malignancies

Kim TY, Ryoo BY, Im YH, Kang YK, Lee SJ, Bang YJ, Kim NK

  • KMID: 2137110
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):44-52.
PURPOSE: The cytotoxicity by 5-fluorouracil (5-FU) is mediated by inhibition of thymi- dylate synthase (TS), which is a rate-limiting enzyme for DNA synthesis. To test whether the resistance to 5-FU would be...
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Expression of Prostatic Carcinoma Oncogene PTI - 1 in Prostatic Carcinoma , Prostatic Intraepithelial Neoplasia and Benign Prostatic Hyperplasia Using in situ PCR

Lee TJ, Park ES, Yoo JH

  • KMID: 2137121
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):136-147.
PURPOSE: Prostatic tumor induced gene-1 (PTI-1) is a mutated human EF-la and putative prostatic carcinoma tumor-inducing oncogene, that is differently expressed in prostatic cancer and benign prostatic hyperplasia. And, it is more sensitive...
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Tumor Angiogenesis as a Predictor of Malignancy Potential and Prognosis in Gastric Carcinoma

Kang CW, Kim HH, Kim YH, Cho SH, Kim SS, Roh MS, Hong SH, Kim CR

  • KMID: 2137107
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):19-25.
PURPOSE: In order to evaluate the clinical relevance of angiogenesis in patients with gastric cancer, we investigated the microvessel count in gastric cancer tissues and compared the results with several clinicopathologic factors...
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Personal Experience of 1,000 Breast Cancer Surgeries in Korea

Ahn SH

  • KMID: 2137113
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):68-75.
PURPOSE: A specialized breast surgeon is important to give comprehensive treatments to breast cancer patients. The purpose of this study was to evaluate the characteristics and treatment results of breast cancer patients in...
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The Role of Transbronchial Needle Aspiration for Diagnosis of Bronchogenic Carcinoma

Kim KY, Park JY, Cha SI, Park KS, Kang TK, Kim CH, Jung TH

  • KMID: 2137116
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):93-99.
PURPOSE: Transbronchial needle aspiration (TBNA) has been used for the diagnosis and staging of bronchogenic carcinoma through the flexible bronchoscope. The aim of this study was to investigate the diagnostic role of TBNA...
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Combination Chemotherapy with VP - 16 , Ifosfamide , and Cisplatin ( VIP ) in the Advanced Non - Small Cell Lung Cancer

Cho YS, Kim SY, Kim JH, Yoon HJ, Cho KS

  • KMID: 2137115
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):86-92.
PURPOSE: We conducted a phase II study in previously untreated patients with unresectable stage IIIB or IV non-small cell lung cancer to evaluate the response rate and toxicity of the combination chemotherapy regimen...
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Clinical Significance of Urokinase - type Plasminogen Activator Receptor ( uPAR ) Expression in Breast Cancer Tissues

Gong SJ, Rha SY, Jung HC, Park JO, Yoo NC, Roh JK, Yang WI, Lee KS, Min JS, Kim BS, Chung HC

  • KMID: 2137111
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):53-59.
PURPOSE: Cancer invasion is induced by several proteolytic enzyme systems associated with the destruction of basement membrane and extracellular matrix. Urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor-1 (PAI-1) have been reported as...
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Detection of Human Papillomavirus DNA and p53 , p21 Gene Expression in CIN3 and Uterine Cervical Cancer

Na JH, Choi HS

  • KMID: 2137117
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):100-109.
PURPOSE: Though the etiology of this cancer has not been elucidated, it has been suggested that certain types of human papillomavirus (HPV) and alteration of the p53 gene are closely associated with...
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Relationship of HPV Detection and p53 Expression in Urinary Bladder Cancer

Kee KH, Shin HM, Kim YC

  • KMID: 2137120
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):129-135.
PURPOSE: The purpose of this study was to investigate the relationship between aberrant p53 expression and the presence of human papillomavirus DNA in transitional cell carcinomas of the urinary bladder. MATERIALS AND...
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Application of Gabexate Mesylate IC against MMP - 9 Using ex vivo Model in Gastric Cancer: Prognostic Factor and Selection Criteria for Anti - MMP Treatment

Moon YW, Yang H, Jung HC, Rha SY, Kim TS, Yoo NC, Noh SH, Roh JK, Min JS, Kim BS, Chung HC

  • KMID: 2137106
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):7-18.
PURPOSE: Among the many biological characteristics of cancer, matrix metalloproteinases(MMPs) are essential for tumor invasion and metastasis. The correction of the imbalance between MMPs and tissue inhibitors of matrix metalloproteinase...
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Chromosomal Aberrations in Ovarian Carcinoma Cell Line, SNU - S , Using Chromosome Painting

Kang JS, Kim DW, Chun YH, Park SH

  • KMID: 2137119
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):120-128.
PURPOSE: The characterization of all recognizable chromosomal rearrangements was dis- turbed by technical limitation of conventional cytogenetic methods. Recently, the strong usefullness of generation of chromosome specific painting probes in identification of marker...
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Clinicopathologic Characteristics and p53, c-erbB2, nm23 Protein Expression in Gastric Remnant Cancer

Lee JH, Youn YK, Kim WH, Yu HJ, Suh BJ, Yang HK, Choe KJ, Kim JP

  • KMID: 2137108
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):26-37.
PURPOSE: The goal of this study was to evaluate the clinicopathologic characteristics and to investigate the expression of p53, c-erbB2, and nm23 protein in gastric remnant cancer. MATERIALS AND METHODS: We evaluated the...
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The Incidence of Hereditary Gastric Cancer in Korean

Kim SJ, Cho SJ, Heo SC, Yang HK, Kim WH, Park JG, Lee KU, Choe KJ, Kim JP

  • KMID: 2137105
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):1-6.
PURPOSE: We wanted to determine the incidence of HGC (hereditary gastric cancer) in Korean under the minimal criteria of ICG-HGC (International Collaborative Group on Hereditary Gastric Cancer). MATERIALS AND METHODS: Tumor...
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The Significance of Serum CA 19 - 9 Level in Gastric Adenocarcinoma

Kim YJ, Kim BS, Yook JH, Oh ST, Suh BS, Kim WS, Kim YH, Park KC

  • KMID: 2137109
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):38-43.
PURPOSE: This study was designed to investigate the significance of preoperative serum CA 19-9 level as a prognostic factor and postoperative serum CA 19-9 level as an indicator for recurrence in gastric...
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Expressions of Cell Cycle Control Genes in Human Uterine Cervical Cancer Cells

Ahn JG, Lee TS, Cho JW, Baek WK, Suh SI, Suh MH, Park JW, Cha SD

  • KMID: 2137118
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):110-119.
PURPOSE: Recently, many aspects of biological functions of cyclins, cyclin-dependent kinases (CDKs), CDK inhibitors and Rb gene have been reported, and the cell cycle control genes are considered to act important roles in...
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Tumor - specific Virus Replication and Cytotoxicity of E1B 55 kD - deleted Adenovirus

Kim J, Lee B, Kim J, Ahn JB, Park JO, Yoo NC, Kim JH, Roh JK, Min JS, Kim BS, Lee H

  • KMID: 2137127
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):200-209.
PURPOSE: To overcome the limitations of cancer gene therapy using replication-incom- petent adenovirus, we generated E1B 55 kD-deleted adenovirus (YKL-1) by polymerase chain reaction (PCR) and homologous recombination. We then investigated tumor-specific virus replication...
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