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20 results

Secretory Carcinoma of the Breast in Three Year-old Girl: A Case report

Noh WC, Paik NS, Cho KJ, Chung JH, Nam SK, Choe DH, Moon NM

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):822-826.
Secretory carcinoma is one of the least common forms of breast cancer and demonstrates distinctive clinical and pathological characteristics. We herein report a case of secretory carcinoma of the breast...
A Case of Triple-Alkylating Regimen and Peripheral Blood Stem Cell Transplantation for a Patient with Relapsed Ovarian Carcinoma

Lee JM, Cho SG, Park JN, Hong YS, Kim HK, Namkoong S, Lee KS, Kim CC

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):817-821.
Despite an aggressive surgical debulking followed by front-line chemotherapy, most patients with advanced ovarian carcinoma die of drug-resistant disease. Drug resistance can be overcome in a subset of patients with...
Immunohistochemical Expression of p53 and Cathepsin D in Prostatic Carcinoma

Kim DJ, Kim EH, Yang SH, Kim CJ

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):810-816.
PURPOSE: To evaluate the prognostic significances of p53 and cathepsin D in the prostatic carcinoma, we compared them to other prognostic factors, such as nuclear grade and clinical stage. MATERIALS AND...
Correlation between Genetic Polymorphism of CYP2D6 and CYP1A1 and Susceptibility of Renal Cell Carcinoma in Korean

Park KW, Jung SI, Jung GW, Kwon HY, Jeong JS, Chun JH, Yoon JH

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):801-809.
PURPOSE: Many of the enzymes handling environmental factors are polymorphic and may confer variable susceptibility to renal cell carcinoma (RCC). Among those, the author studied genetic polymorphisms of CYP2D6 (B...
BACOD/EISHAP Alternating Combination Chemotherapy for Intermediate and High Grade Non-Hodgkin's Lymphoma

Kang JH, Park YH, Kim SJ, Yun JC, Lee GW, Kim HG, Hwang IG, Lee WS, Jang JS, Lee JS

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):793-800.
PURPOSE: We conducted a phase II study to determine the antitumor activity of BACOD/EISHAP alternating 9-drug chemotherapy in previously untreated patients with intermediate or high grade non-Hodgkin's lymphoma (NHL). MATERIALS AND...
The Mechanism of Retinoic Acid-induced Growth Suppression in Head and Neck Squamous Cancer Cell Lines

Kim SJ, Paek CW, Seo JH, Choi CW, Kim BS, Shin SW, Kim YH, Kim JS, Kim A, Lee KN, Kim SH, Choi G, Yoo YA

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):783-792.
PURPOSE: Retinonic acid (RA) has been reported to induce differentiation and growth inhibition in various head and neck squamous cancer cell (HNSCC) lines. We hypothesized that this growth inhi bition might...
Preliminary Results of Postoperative Radiotherapy after Breast Conserving Surgery in Early Breast Cancer

Chang SH, Huh SJ, Yang JH, Lim DH, Nam SJ, Yoon SS, Ahn YC, Kim DY, Park SW, Kim MK

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):775-782.
PURPOSE: To evaluate treatment results of breast conserving surgery and radiation therapy including survival rates, patterns of failure, and complication and to analyze prognostic factors. MATERIALS AND METHODS: Retrospective analysis was...
Antiangiogenesis Gene Therapy Using Adenovirus-mediated Antisense-VEGF in Glioblastoma Multiforme

Im SA, Kim JS, Nam E, Lee SN

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):764-774.
PURPOSE: Vascular endothelial growth factor (VEGF) is a major positive effector of angiogenesis. We investigated the mechanism of tumor growth inhibition by adenoviral transfer of antisense- VEGF in glioma and...
Nausea and Vomiting Induced by Conventional Fractionated Radiotherapy on Abdomen

Kim WD, Park WY

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):757-763.
PURPOSE: A retrospective study was intended to assess the incidence, severity, and risk factors of abdominal radiotherapy induced nausea and vomiting and to evaluate the effect of antiemetic drugs like...
Cell Cylce Regulatory Effects of Cyclic AMP in Cancer Cells Which Lack Wild-type p53

Jang JS, Kang JH, Park BK, Hwang SG

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):750-756.
PURPOSE: The activator of protein kinase A, cyclic AMP, has been a recognized growth inhibitor of certain cell types. The present study aimed to investigate the effects of dibutyryl cAMP...
Uptake of Ga-67 by Cultured Cells: Transferrin-dependent and Transferrin-independent Mechanisms

Sohn MH, Lim ST, Kwak JY, Yim CY

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):742-749.
PURPOSE: We determined whether the uptake of Ga-67 by cultured cells occur by both transferrin (Tf)-dependent and independent mechanisms and the mechanism and magnitude of its uptake may vary as...
Salicylate Induced Apoptosis in A549 Cells

Park YH, Seol JI, Kim HI, Kim MJ, Lee HJ, Kim SA, Kim CJ, Chung JH

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):734-741.
PURPOSE: Nonsteroidal antiinflammatory drugs (NSAIDs) have been shown to exist chemo preventive activity against colon cancers. In this study, we examined whether salicylate affects the survival of A549 cells, and investigated...
Changes of Telomerase Activity by Protein Kinase C Modulators in Human Ovarian Cancer Cell Lines

Hur SY, Lee JM, Namkoong S, Kim JW

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):724-733.
PURPOSE: This study was designed to find out whether protein kinase C (PKC) may affect telomerase activity in human ovarian cancers. MATERIALS AND METHODS: To determine whether PKC modulators influence PKC...
Results of Radio-thermotherapy in Stage IIIb Uterine Cervical Cancer Local response, survival rate and analysis of prognostic factor

Moon CW

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):714-723.
PURPOSE: This retrospective study was conducted to obtain local response and survival rates, and to analyze prognostic factors affecting survival of patients treated with radio-thermotherapy for stage IIIb uterine cervical...
The Inefficiency of Routine Performance of a Batch of Tests in the Clinical Staging Work-up of Cervical Carcinoma

Shim SS, Kim JW, Kim YB, Rho JW, Lee CM, Park NH, Song YS, Kang SB, Lee HP

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):705-713.
PURPOSE: This study was to evaluate the efficiency of routine performance of a batch of tests in the clinical staging work-up of cervical carcinoma. MATERIALS AND METHODS: The medical records were...
Venous Irritation Incidence Associated with Vinorelbine Tartrate Injection Time

Hur KW, Jung JE, Seo JH, Choi CW, Kim BS, Shin SW, Kim YH, Kim JS

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):699-704.
PURPOSE: This study was to determine the incidence and severity of venous irriation in patients receiving vinorelbine tartrate (Navelbine ) in combination chemotherapy. MATERIAL AND METHODS: Twenty four patients histologically confirmed...
A Phase II Study with Vinorelbine and Carboplatin in Patients with Advanced Non-small Cell Lung Cancer

Kim JL, Kim BS, Na BJ, So MJ, Lee JH, Chung OY, Lee GL, Roh YH

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):690-698.
PURPOSE: To evaluate the efficacy and safety of vinorelbine and carboplatin in advanced non- small-cell lung cancer (NSCLC). MATERIALS AND METHODS: Between August 1998 and July 1999, 25 patients were enrolled....
Concurrent Chemoradiation Therapy with Cisplatin and Oral Etoposide for Locally Advanced Non-small Cell Lung Cancer

Paek CW, Yoon SY, Seo JH, Choi CW, Kim BS, Shin SW, Kim YH, Shim JJ, Kang KH, Kim JS, Kim CY, Choi MS, Choi YH, Kim KT

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):682-689.
PURPOSE: Prognosis of locally advanced inoperable non-small cell lung cancer (NSCLC) treated with radiation therapy alone has been disappointing. In recent years, concurrent chemoradiation therapy has potential of improving both...
Analysis of Clinicopathological Factors Associated with Lymph Node Metastasis in Early Gastric Cancer Review of 2,137 cases

Kwak CS, Lee HK, Cho SJ, Yang HK, Lee KU, Choe KJ, Kim JP

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):674-681.
PURPOSE: The majority of patients with early gastric cancer show long-term survival after surgery. So a special attention must be directed to preserving gastric function in these patients. When node-negative...
Expression of CD44 Standard, Variant 6 and Relationship to the Lymph Node Metastasis in Gastric Adenocarcinoma

Lee JH, Yu HJ, Suh BJ, Ju M, Lee HK, Kim JP

  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):665-673.
PURPOSE: The transmembrane glycoprotein CD44 exists in a variety of isoforms generated by alternative splicing of the pre-mRNA. We studied the role of CD44-standard (CD44s) and CD44-variant6 (CD44v6) in gastric...

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