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The Current Trend of Avian Influenza Viruses in Bioinformatics Research

Ahn I, Son HS

OBJECTIVES: Since the first human infection from avian influenza was reported in Hong Kong in 1997, many Asian countries have confirmed outbreaks of highly pathogenic H5N1 avian influenza viruses....
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Strategy Considerations in Genome Cohort Construction in Korea

Sung J, Cho SI

Focusing on complex diseases of public health significance, strategic issues regarding the on-going Korean Genome Cohort were reviewed: target size and diseases, measurements, study design issues, and followup strategy of...
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Change of Cognitive Function and Associated Factors among the Rural Elderly: A 5-Year Follow-up Study

Kim SK, Kang PS, Hwang TY, Sakong J, Lee KS

OBJECTIVES: This prospective population-based cohort study was conducted to evaluate the risk factors of cognitive impairment and the degree of cognitive function change through a 5-year follow-up. METHODS: The...
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General Population Time Trade-off Values for 42 EQ-5D Health States in South Korea

Jo MW, Lee SI

OBJECTIVES: This study was conducted to elicit quality weights for 42 EQ-5D health states with the time trade-off (TTO) method from the general population of South Korea. METHODS:...
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Association of Social Support and Social Activity with Physical Functioning in Older Persons

Park K, Lee Y

OBJECTIVES: According to Rowe and Kahn (1998), successful aging is the combination of a low probability of disease, high functioning, and active engagement with life. The purpose of this...
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Ethical Considerations in Genomic Cohort Study

Choi EK, Kim OJ

During the last decade, genomic cohort study has been developed in many countries by linking health data and genetic data in stored samples. Genomic cohort study is expected to find...
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High Throughput Genotyping for Genomic Cohort Study

Park WY

Human Genome Project (HGP) could unveil the secrets of human being by a long script of genetic codes, which enabled us to get access to mine the cause of diseases...
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A Review of Power and Sample Size Estimation in Genomewide Association Studies

Park AK, Kim H

Power and sample size estimation is one of the crucially important steps in planning a genetic association study to achieve the ultimate goal, identifying candidate genes for disease susceptibility, by...
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The Levels of Psychosocial Stress, Job Stress and Related Factors of Medical Doctors Practicing at Local Clinics

Kang MK, Kang YS, Kim JR, Jeong BG, Park KS, Kam S, Hong DY

OBJECTIVES: This study was conducted to investigate the levels of psychosocial stress, job stress and their related factors among medical doctors practicing at local clinics. METHODS: A survey...
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The Determinants of Purchasing Private Health Insurance in Korean Cancer Patients

Lim JH, Kim SG, Lee EM, Bae SY, Park JH, Choi KS, Hahm MI, Park EC

OBJECTIVES: The aim of this study is to identify factors determining the purchase of private health insurance under the mandatory National Health Insurance(NHI) system in Korea. METHODS: The data...
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The Impacts of Obesity on Psychological Well-being: A Cross-sectional Study about Depressive Mood and Quality of Life

Kim JY, Oh DJ, Yoon TY, Choi JM, Choe BK

OBJECTIVES: The aim of this study was to assess whether individuals who visit clinics to ask medical help for obesity treatment depict comparable levels of depression, body dissatisfaction, eating...
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Statistical Issues in Genomic Cohort Studies

Park S

When conducting large-scale cohort studies, numerous statistical issues arise from the range of study design, data collection, data analysis and interpretation. In genomic cohort studies, these statistical problems become more...
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Using Tobit Regression Analysis to Further Understand the Association of Youth Alcohol Problems with Depression and Parental Factors among Korean Adolescent Females

Delva J, Kaylor AG, Steinhoff , Shin DE, Siefert K

OBJECTIVES: This study characterized the extent to which youth depressive symptoms, parental alcohol problems, and parental drinking account for differences in alcoholrelated problems among a large sample of adolescent...
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Impact of an Early Hospital Arrival on Treatment Outcomes in Acute Ischemic Stroke Patients

Kwon YD, Yoon SS, Chang H

OBJECTIVES: Recent educational efforts have concentrated on patient's early hospital arrival after symptom onset. The purpose of this study was to evaluate the time interval between symptom onset and...
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Developmental Toxicity by Exposure to Bisphenol A Diglycidyl Ether during Gestation and Lactation Period in Sprague-dawley Male Rats

Hyoung UJ, Yang YJ, Kwon SK, Yoo JH, Myoung SC, Kim SC, Hong YP

OBJECTIVES: Bisphenol A diglycidyl ether (BADGE) is the major component in commercial liquid epoxy resins, which are manufactured by co-reacting bisphenol A with epichlorohydrin. This study was performed to...
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