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Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman: A Case Report and Literature Review

Jang NR, Lee DH, Jang EJ, Bae YK, Baek J, Jang MH

Gynandroblastoma is an extremely rare sex cord-stromal tumor with both female (granulosa cell tumor) and male (Sertoli-Leydig cell tumor) elements. Juvenile granulosa cell tumors are also very rare and are...
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Bile Granuloma Mimicking Peritoneal Seeding: A Case Report

Jeong H, Lee HW, Jung HR, Hwang I, Kwon SY, Kang YN, Kim SP, Choe M

Laparoscopic cholecystectomy is a widely used treatment method for most cholelithiasis and is a relatively safe procedure. Foreign body granulomatous reaction to bile or gallstone spillage during laparoscopic cholecystectomy has...
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p40 Immunohistochemistry Is an Excellent Marker in Primary Lung Squamous Cell Carcinoma

Affandi KA, Tizen NM, Mustangin , Zin RR

BACKGROUND: Lung cancer is the third most common cancer worldwide. With major advances in the molecular testing of lung cancers and the introduction of targeted therapies, the distinction between adenocarcinoma...
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Abrupt Dyskeratotic and Squamoid Cells in Poorly Differentiated Carcinoma: Case Study of Two Thoracic NUT Midline Carcinomas with Cytohistologic Correlation

Lee T, Choi S, Han J, Choi YL, Lee K

Cytologic diagnosis of nuclear protein in testis (NUT) midline carcinoma (NMC) is important due to its aggressive behavior and miserable prognosis. Early diagnosis of NMC can facilitate proper management, and...
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C-reactive Protein Overexpression in the Background Liver of Hepatitis B Virus–Associated Hepatocellular Carcinoma Is a Prognostic Biomarker

Shin JH, Yu E, Kim EN, Kim CJ

BACKGROUND: Chronic hepatitis B virus (HBV) infection is a leading cause of hepatocellular carcinoma (HCC). Peripheral blood C-reactive protein (CRP) concentration and CRP overexpression in HCC cells are proven to...
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Differential MicroRNA Expression between EGFR T790M and L858R Mutated Lung Cancer

Kim JY, Lee WJ, Park HY, Kim A, Shin DH, Lee CH

BACKGROUND: MicroRNAs (miRNAs) are short, non-coding RNAs that mediate post-transcriptional gene regulation. They are commonly deregulated in human malignancies, including non-small cell lung cancer (NSCLC). The aim of this study...
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Chronic Placental Inflammation as a Risk Factor of Severe Retinopathy of Prematurity

Kim CY, Jung E, Kim EN, Kim CJ, Lee JY, Hwang JH, Song WS, Lee BS, Kim EA, Kim KS

BACKGROUND: Chronic placental inflammation (CPI) has been implicated in the pathogenesis of diseases in premature infants, whereas retinopathy of prematurity (ROP) is a major complication primarily affecting preterm and very...
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Significance of Intratumoral Fibrosis in Clear Cell Renal Cell Carcinoma

Joung JW, Oh HK, Lee SJ, Kim YA, Jung HJ

BACKGROUND: Intratumoral fibrosis (ITF) is a frequent histologic finding in solid organ tumors. Renal cell carcinoma (RCC) is a highly vascularized tumor with different shapes and degrees of ITF and...
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Interleukin-31, Interleukin-31RA, and OSMR Expression Levels in Post-burn Hypertrophic Scars

Lee MY, Shin E, Kim H, Kwak IS, Choi Y

BACKGROUND: Although several studies have shown the role of interleukin-31 (IL-31) and its receptors in inducing pruritus in certain skin disorders, knowledge of its role in post-burn hypertrophic scars is...
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Prognostic Role of Metastatic Lymph Node Ratio in Papillary Thyroid Carcinoma

Pyo JS, Sohn JH, Chang K

BACKGROUND: The aim of this study is to elucidate the clinicopathological significances, including the prognostic role, of metastatic lymph node ratio (mLNR) and tumor deposit diameter in papillary thyroid carcinoma...
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Prognostic Significance of EPHB2 Expression in Colorectal Cancer Progression

Jang BG, Kim HS, Chang WY, Bae JM, Kang GH

BACKGROUND: A receptor tyrosine kinase for ephrin ligands, EPHB2, is expressed in normal colorectal tissues and colorectal cancers (CRCs). The aim of this study was to investigate EPHB2 expression over...
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An Immunohistochemical and Polarizing Microscopic Study of the Tumor Microenvironment in Varying Grades of Oral Squamous Cell Carcinoma

Khalid A, Siddiqui S, Bordoloi B, Faizi N, Samadi F, Saeed N

BACKGROUND: Invasion of epithelial cells into the connective tissue brings about massive morphological and architectural changes in the underlying stroma. Myofibroblasts reorganize the stroma to facilitate the movement of tumor...
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