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Polymorphisms of the Dopamine Receptor Genes in Alcoholism

Ryu SH

  • KMID: 2202792
  • J Korean Soc Biol Psychiatry.
  • 2002 Jul;9(1):15-24.
Even though alcoholism is a multi-factorial psychiatric disorder, it is reasonable to suppose that genetic factors play a substantial role in the manifestation of this disorder. Because alcohol is the...
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Serotonin(2A) Receptor Gene Promoter Polymorphism in Mood Disorder and Mood-Related Disorders

Chee IS

  • KMID: 2202790
  • J Korean Soc Biol Psychiatry.
  • 2002 Jul;9(1):3-7.
Genes involved in the serotonin system are good candidates for the pathogenesis of mood disorder and mood-related disorders, such as eating disorder, obsessive-compulsive disorder, alcoholism, and suicide. Serotonin type 2A(5-HT2A)...
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The association between Korean Schizophrenics and Catalase Gene Polymorphism

Park JK, Lee HK, Bahn GH, Park JD, Chung JH, Chang HI

  • KMID: 2202797
  • J Korean Soc Biol Psychiatry.
  • 2002 Jul;9(1):62-67.
OBJECTIVE: There is increasing evidence that free radical-mediated CNS neuronal dysfunction is involved in the pathophysiology of schizophrenia. This study was performed to examine the relationship between antioxidant defense system...
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Dopamine Transporter Gene Polymorphism In ADHD

Shin DW

  • KMID: 2202791
  • J Korean Soc Biol Psychiatry.
  • 2002 Jul;9(1):8-14.
Patients with attention deficit hyperactivity disorder(ADHD) have symptoms of inattention, hyperactivity, impulsivity. Symptoms of ADHD are responsive to medications such as methylphenidate, dextroamphetamine, pemoline, and bupropion. The functional change of...
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The Use of Pharmacogenomic Method for the Prediction of Antidepressant Responsiveness

Kim DK, Lim SW

  • KMID: 2202793
  • J Korean Soc Biol Psychiatry.
  • 2002 Jul;9(1):25-33.
Serotonin transporter(5-HTT) is one of the major action site of antidepressants in neuronal cells. According to the recent studies, it is known that the functional polymorphism in the promoter region...
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Relationships between Nailfold Plexus Visibility, and Clinical Variables and Neuropsychological Functions in Schizolphrenic Patients

Kang DY, Jang HR

  • KMID: 2202796
  • J Korean Soc Biol Psychiatry.
  • 2002 Jul;9(1):50-61.
OBJECTIVES: High nailfold plexus visibility can reflect central nervous system defects as an etiologic factor of schizophrenia indirectly. Previous studies suggest that this visibility is particularly related to the negative...
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5-HTTLPR and Long-term effect of Antidepressant Treatement in Korean Depressive Patients

Lee HY, Ham BJ, Lee MS

  • KMID: 2202794
  • J Korean Soc Biol Psychiatry.
  • 2002 Jul;9(1):34-41.
BACKGROUND: Since serotonin neurotransmission plays an important role in the pathophysiology of depression, the drug that acts on serotonin transporter can be an effective antidepressant. The aim of this study...
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Association of Genetic Polymorphisms of Aldehyde Dehydrogenase II and CYP2E1 and Clinical Characteristics of Patients with Alcohol Dependence

Chung IW, Kim YR, Chi KH, Kim H

  • KMID: 2202795
  • J Korean Soc Biol Psychiatry.
  • 2002 Jul;9(1):42-49.
OBJECTIVE: This study was to explore the relation of genetic polymorphisms of ALDH2 and CYP2E1 to clinical characteristics of alcoholic patients and alcohol induced liver damage. METHODS: The genotype and allele...
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