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cDNA Microarray in Psychiatry

Yang BH, Kim JY

  • KMID: 1899245
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):123-130.
The development of inexpensive high throughput methods to identify individual DNA sequences is important to the future growth of medical genetics. This has become increasingly apparent as psychiatric geneticists focus...
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Molecular Application in Psychiatry

Choi IG

  • KMID: 1899244
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):115-122.
The development of molecular biology has brought many changes in psychiatry. Molecular biology makes us possible to know the cause of mental disorders that provide the way to prevent the...
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Combination & Augmentation Strategies in the Treatment of Depressive Disorder

Kim HS

  • KMID: 1899246
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):131-139.
Even the pharmacotherapy is more effective than placebo for the treatment of depression, the outcome of pharmacoltherapy remains unsatisfactory for many patients. Apart from side effects, there are two major...
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Comparison of Global Field Power Measurement and Conventional Method in Multi-channel Auditory Event Related Potential P300 Determination

Jeon YW, Han SI

  • KMID: 1899253
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):180-185.
OBJECTIVE: The present study was designed to compare Global field Power Measurement and conventional method in P300 determination. METHOD: The subjects were composed of patients(N=20) with schizophrenia by DSM-IV and normal...
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Cost Effectiveness of Clozapine and Risperidone in

Nam JW, Lee MS, Jeong IK, Kwak DI

  • KMID: 1899256
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):198-205.
OBJECTIVES: Risperidone and clozapine beling to a new generation of antipsychotics that are reportedly more effective and better tolerated than conventional neuroleptics. However, each of these agents costs far more...
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The Association between the Dopamine D5 Receptor Genotype and Treatment Response for Korean Schizophrenic Patients

Kang SM, Lee MS, Rhee CS

  • KMID: 1899250
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):159-163.
BACKGROUND: Dopamine receptors are strong candidates for involvement in schizophrenia and are target of a wide variety of antipsychotics. Dopamine D5 receptor(DRD5) gene polymorphisms may be associated with various treatment...
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Association of Dopamine D4 Receptor(DRD4) Gene Polymorphism with Korean Schizophrenic Patients

Lee HS, Lee MS, Han DJ, Lee HJ

  • KMID: 1899249
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):152-158.
BACKGROUND: No association between schizophrenia and dopamine D4 receptor polymorphisms have been reported. Despite these results, it is premature to exclude the association. It has been suggested that the susceptibility...
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The Influence of Negative Emotion to Cortical Activity Induced by Auditory Verbal Imagery in Patients with Schizophrenia

Lee HS, Kim JW, Kim YL

  • KMID: 1899252
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):174-179.
OBJECTIVES: Cognitive psychological models propose that auditory hallucinations arise from a problem with monitoring one's auditory verbal imagery. Most auditory hallucinations are derogatory in content and accompany negative emotions. If...
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Effects of Long-Term Alcohol Treatment Combined with Vitamins or Piracetam on the Ultrastructure of Rat Hippocampal and Cerebellar Neurons

Sohn CH, Lee SI, Kwak JS, Jeong IW

  • KMID: 1899251
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):164-173.
This study was carried out to investigate the direct neurotoxicity of alcohol on CNS and the effects of piracetam or vitamins on ultrastructural changes of the rat cerebellar and hippocampal...
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Restriction Fragment Length Polymorphism of Interleukin-10 Gene in Major Depression

Jun TY, Pae CU, Lee CT, Bahk WM, Kim KS

  • KMID: 1899248
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):147-151.
OBJECTIVE: Major depression is known to have immunologic dysfunctions, the recent studies revealed that cytokines including Il-6 and IL-1beta were increased in patients with major depression. Since molecular genetic methods...
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No Association of CYP2D6*4 and CYP2D6*10 Polymorphisms with Tardive Dyskinesia in Korean Schizophrenics

Woo SI, Kang DW, Seo HG, Kim BJ, Lee IS, Jeong GH, Park SY, Jung CY, Lee HC, Jeong KC, Sohn JW

  • KMID: 1899247
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):140-146.
P450 CYP2D6 enzyme(debrisoquine hydroxylase) is known to metabolize many neuroleptics and some genetic polymorphisms in the CYP2D6 gene were reported to be associated with tardive dyskinesia(TD). We investigeted the association...
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Predicting Factors of Discontinuation of medication after Cognitive Behavioral Therapy for Panic Disorder

Choi YH, Park KH, Kim HS, Ha OR

  • KMID: 1899254
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):186-190.
OBJECTIVE: The authors experienced that cognitive begavioral therapy(CBT) could replace medication for controlling panic attacks and anticipatory anxiety symptoms. The objective of this study was finding out predicting factors of...
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The Cardiovascular Effect of Risperidone

Choi SJ, Cheon JS, Choi YT

  • KMID: 1899255
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):191-197.
OBJECTIVES: Risperidone is a new antipsychotic drug developed to overcome the therapeutic limitation of conventional antipsychotics. It responses to negative as well as positive symptoms by blocking both dopaminergic and...
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