- Animal Models of Alzheimer's Dementia
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Woo SI
- KMID: 2334613
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):149-152.
Transgenic mice models of Alzheimer's disease were produced by overexpressing APP(amyloid precursor protein) mutant and presenilin mutant genes using the promotors that induced neuronal expression. The neuropathologies, electrophysiological changes and... -
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- Experimental Models of Depression
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Chung YI
- KMID: 2334615
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):161-169.
There are a number of approaches in developing experimental models for depression. but there is no such thing as a best model for depressive syndrome. Animal models are subject to... -
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- The Effects of Estrogen Replacement Therapy on Depressive Symptoms and Attention in Postmenopaual Woman
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Kee BS, Kim SY, Nam BW, Min KJ, Lee SH
- KMID: 2334624
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):235-239.
OBJECTIVES: The purpose of this study was to evaluated the difference of depressive symptoms and attention between estrogen user and non-user in postmenopausal women. METHODS: 30 Estrogen users and 30 non-users... -
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- Antipsychotics Induced Etrapyramidal Symptoms in Schizophrenics in Relation to Cytochrome P450 2D6 Genotype
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Lee MS, Nam JW
- KMID: 2334618
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):189-192.
The genetically determined CYP2D6 activity may be considered to be associated with antipsychotic induced extrapyramidal side effects with inter-individual variation. Genetic polymorphism of CYP2D6 was determined by polymerase chain reaction(PCR)... -
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- Lower Serum Cholesterol Level is Associated with More Serious Injury in psychiatric Patients with Suicide Attempt
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Kim YK, Lee HJ, KIm JY, Lee MS, Choi SH
- KMID: 2334623
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):227-234.
An association of low total cholesterol in blood with psychiatric diseases and suicidal behavior has been suggested. As part of an attempt to further explore this relationship, we examine first,... -
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- Nefazodone and Associated Perceptual Disturbance : A Report of Four Cases
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Kim JY, Song HS, Cho BH, Kim YK
- KMID: 2334628
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):259-263.
Nefazodone, a newer antidepressant is a phenylpiperazine derivative that inhibits the reuptake of both norepinephrine and serotonin, and antagonizes 5-HT2A and alpha1 adrenergic receptors. Compared with SSRIs nefazodone caused the... -
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- Sleep patterns in Chronic Schizophrenic patients Treated with Clozapine
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Shin IS, Lee SH, Yoon JS, Yoon BY
- KMID: 2334626
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):246-253.
OBJECTIVES: Daytime drowsiness or sedation and changes in night sleep are commonly seen in patients treated with clozapine. There is, however, very limited informatio on their degree and nature during... -
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- VNTR Polymorphism of Tyrosine Hydroxylase Gene Intron 1 in Schizophrenics
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Paik IH, Toh KY, Lee CU, Kim JJ, Lee SJ, Lee C
- KMID: 2334616
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):170-175.
Until recently, the etiology of schizophrenia was generally attributed to abnormalities in dopaminergic neurotransmission. Specifically, an excess of dopaminergic activity in the mesolimbic system has been postulated to produce the... -
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- Experimental Models of Schizophrenia
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Cheon JS
- KMID: 2334614
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):153-160.
Animal models can provide a useful tool for the study of some aspects of psychiatric disorders and their treatment. The four criteria for the evaluation of animal models of psychiatric... -
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- Antibodies to Heat Shock Protein 70kDa and 90kDa in the Patients with Schizophrenia, and Their Relationship with Clinical Variables
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Kim JJ
- KMID: 2334620
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):202-208.
Schizophrenia has many clinical expression and probably different etiologic factors. Infections, autoimmune mechanism and related neurodevelopmental abnormalities have been suggested as possible etiologic factors of schizophrenia. It has been reported... -
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- A Case of Fluoxetine-induced Mania & Suicidal Ideation in Obsessive-Compulsive Disorder
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Lee SH, Lee MS
- KMID: 2334627
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):253-258.
The fluoxetine is one of the most frequently prescribed drugs for the treatment of depression and obsessive-compulsive disorder(OCD). This has been know as one of the most safest medication. But... -
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- Effects of Opioid Agonists on the Suppressed Spontaneous Alternation Behaviour in Rats
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Lee GC, Jeon SI, Lee JH, Choi YM, Kim SH, Ryu JH, Choi M, Chang HI
- KMID: 2334619
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):193-201.
This study was designed to evaluated the effects of opioid receptor agonists on the spontaneous alternation behaviour in an animal model of obsessive-compulsive disorder in rats. According to the theory... -
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- Changes in Blood Superoxide Dismutase Activities after Alcohol Withdrawal
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Cheon JS, Lee KC, Oh BH
- KMID: 2334622
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):219-226.
OBJECTIVES: The aims of this study were to evaluate changes in plasma superoxide dismutase(SOD) activities in alcohol depedence, to fine out variables to influence on the SOD activities, and finally... -
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- The Influence of Estrogen on Dopamine Metabolites in Schizophrenia
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Cheon JS, Lee JH, Oh BH
- KMID: 2334621
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):209-218.
OBJECTIVES: The aims of this study were to discriminate the clinical differences, to measure the estrogen and homovanillic acid levels. to evaluate a correlation between estrogen and homovanillic acid. and... -
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- Effects of Olanzapine on the Schedule-Induced polydipsic Rats
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Lee GC, Lee JH, Ha JM, jeong JH, Jeong HK, Lee KK, Kim HW, Chang HI
- KMID: 2334625
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):240-245.
OBJECT: This study was designed to evaluate the effects of olanzapine on the schedule-induced polydipsia(SIP) which is one of animal model of obsessive-compulsive disorder in rats. We administered olanzapine as... -
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- Effects of Alcohol on Neurocognitive Function, Psychomotor Performance and Subjective Response in Koreans with Different ALDH2 Genotypes
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Sin IS, Yoon JS, Kim H, Lee HY, Yoon BH, Lee H, Jung JS
- KMID: 2334617
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):176-188.
OBJECTIVE: The purpose of this study was to evaluated the effects of alcohol on neurocognitive function, psychomotor performance and subjective response in healthy Korean adults with different ALDH2 genotypes. METHOD: A... -
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