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Newly Developed Mecometer Method for Objective Assessment of Meconium Content

Park SK, Shin SH

We developed a new method for an objective assessment of the meconium content in amniotic fluid. By establishing a standard scale through a serial dilution of a known amount of...
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Development of Multiple Pigmented Nevi Within Segmental Nevus Depigmentosus

Shim JH, Seo SJ, Song KY, Hong CK

Nevus depigmentosus is a stable and well-circumscribed congenital hypomelanosis that may be in an isolated, dermatomal or systemic form. An 18-yr-old Korean man with segmental nevus depigmentosus developed multiple pigmented...
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Donor Specific Response of Estrogen and Progesterone on Cultured Human Melanocytes

Im S, Lee ES, Kim W, On W, Kim J, Lee M, Kang WH

The mechanisms of estrogen and progesterone in human cutaneous pigmentation are largely unknown. The molecular identification of estrogen receptor (ER) and progesterone receptor (PR) in the human melanocytes is of...
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Intrasellar Schwannoma Mimicking Pituitary Adenoma: A Case Report

Whee SM, Lee JI, Kim JH

Intrasellar location of schwannoma is extremely rare, although intracranial schwannomas account for up to 8% of all primary brain tumors. An unusual case of an intrasellar schwannoma radiographically and clinically...
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FKBP-12 Exhibits an Inhibitory Activity on Calcium Oxalate Crystal Growth in Vitro

Han IS, Nakagawa Y, Park JW, Suh MH, Suh SI, Shin SW, Ahn SY, Choe BK

Urolithiasis and calcium oxalate crystal deposition diseases are still significant medical problems. In the course of nephrocalcin cDNA cloning, we have identified FKBP-12 as an inhibitory molecule of calcium oxalate...
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The Prevalence of Mental Retardation Among Third Grade Elementary School Children in the Suwon Area, Korea

Yim SY, Yu HH, Lee IY

The purpose of this study was to estimate the prevalence of mental retardation (MR) in Korea. The study population comprised 1,757 third-grade elementary school children residing in a single school...
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Prenatal Diagnosis of Tetralogy of Fallot Associated with Chromosome 22q11 Deletion

Oh DC, Min JY, Lee MH, Kim YM, Park SY, Won HS, Kim IK, Lee YH, Yoo SJ, Ryu HM

Microdeletion of 22q11 is responsible for DiGeorge syndrome, velocardiofacial syndrome, congenital conotruncal heart defects, and related disorders. We report our experiences on prenatal diagnosis by fluorescence in situ hybridization (FISH)...
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Trilateral Retinoblastoma: A Case Report

Cho EY, Suh YL, Shin HJ

Trilateral retinoblastoma is a rare, but well recognized syndrome. These tumors usually occur in the pineal, parasellar, or suprasellar regions several years after successful management of ocular retinoblastomas without evidence...
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Cleft lip and Palate Incidence Among the Live Births in the Republic of Korea

Kim S, Kim WJ, Oh C, Kim JC

We present an epidemiologic study of cleft lip and palate in the Republic of Korea from January 1, 1993 through December 31, 1993. In 1993, the number of total live...
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Change of Hyperexcitability of Hippocampus by Cyclosporin A and Its Modulatory Action by Fentanyl

Choi BJ, Whang KT

Cyclosporin A is used to treat patients with immune-mediated diseases, chronic diseases requiring organ transplantation, or malignancies. These conditions often require higher cyclosporin A doses, which may be toxic to...
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Undifferentiated Spondyloarthropathy in Korea: Focusing on Peripheral Arthritis

Kim TH, Lee HS, Ji JD, Jun JB, Jung S, Bae SC, Yoo DH, Kim SY

Undifferentiated spondyloarthropathy (USpA) includes the forms that do not meet criteria for the established categories of spondyloarthropathy. The clinical spectrum of USpA is therefore wide and few studies have been...
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Penicillin-resistant Aerococcus viridans Bacteremia Associated with Granulocytopenia

Uh Y, Son JS, Jang IH, Yoon KJ, Hong SK

Aerococcus viridans, a catalase-negative gram-positive coccus rarely causing bacteremia, was isolated from blood cultures of a 52-yr-old man under the gran-ulocytopenic condition. The isolate showed the typical characteristics of A....
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A Cohort Study on the Association between Psychotropics and Hip Fracture in Korean Elderly Women

Bae JM, Koo HW, Jung KO, Park BJ

To test the hypothesis that the intake of psychotropics may increase the risk of hip fracture, a cohort study was conducted upon elderly Korean women. The Korean Elderly Pharmacoepidemiology Cohort...
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Association Between FcgammaR IIa and IIIa Polymorphism and Clinical Manifestations in Korean Patients with Adult-Onset Still's Disease

Oh YB, Ahn JY, Lee HS, Kim TH, Jun JB, Jung SS, Bae SC, Kim SY, Yoo DH

High-dose intravenous immunoglobulins alter the disease activity of adult-onset Still's disease (AOSD). Because activation status of FcgammaR is possibly dependent on their genetic polymorphisms, we investigated whether the polymorphisms of...
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Simultaneous Occurrence of Subarachnoid Hemorrhage due to Ruptured Aneurysm and Remote Hypertensive Intracerebral Hemorrhage: Case Report

Lee JK, Lee JH, Kim IY, Kim TS, Jung S, Kim JH, Kim SH, Kang SS

Simultaneous occurrence of aneurysmal subarachnoid hemorrhage (SAH) and hypertensive intracerebral hemorrhage (ICH) is very rare and only two cases have been previously reported in the literatures. We present a case...
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Coexpression of MUC1 with p53 or MUC2 correlates with Lymph Node Metastasis in Colorectal Carcinomas

Jang KT, Chae SW, Sohn JH, Park HR, Shin HS

The alteration of the mucin profile have been known to play a role in colorectal carcinogenesis. MUC1 is up-regulated and MUC2 is down-regulated in colorectalcarcinomas. Overexpression of p53 is frequently...
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Reduced E-Cadherin Expression as a Cause of Distinctive Signet-Ring Cell Variant in Colorectal Carcinoma

Kim HC, Kim HJ, Kim JC

Colorectal signet-ring cell carcinoma (SRCC) is a rare type of adenocarcinoma and presents with distinctive clinicopathological features. This study was performed to assess the biological characteristics of colorectal SRCC regarding...
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Effects of Different Concentrations of Formalin on Paw Edema and Pain Behaviors in Rats

Lee IO, Jeong YS

The aim of this study was to determine whether formalin reliably provokes a paw edema and pain behavior. The paw of male Sprague-Dawley rats were injected with 100 microliter of...
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Hanja Alexia with Agraphia After Left Posterior Inferior Temporal Lobe Infarction: A Case Study

Kwon JC, Lee HJ, Chin J, Lee YM, Kim H, Na DL

Korean written language is composed of ideogram (Hanja) and phonogram (Hangul), as Japanese consists of Kanji (ideogram) and Kana (phonogram). Dissociation between ideogram and phonogram impairment after brain injury has...
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Primary Vesical Actinomycosis: A Case Diagnosed by Multiple Transabdominal Needle Biopsies

Lee KR, Ko YS, Yu JW, Yoon CY, Kim CH, Yoon DK

Primary vesical actinomycosis is an extremely rare disease. In most cases it is misdiagnosed as vesical or urachal tumor and usually diagnosed through post-operative pathologic confirmation. Here we report a...
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