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Association Study Between Brain-Derived Neurotrophic Factor Genetic Polymorphism and Treatment Responses of Selective Serotonin Reuptake Inhibitor in Major Depressive Disorder

Lee YM

  • J Korean Geriatr Psychiatry.
  • 2008 Jun;12(1):34-39.
OBJECTIVES: Recent studies suggest that brain-derived neurotrophic factor (BDNF) may play a critical role in both mechanism of antidepressant action and the pathophysiology of major depressive disorder (MDD). The aim...
A Study on the Association Between Cholineacetyltransferase(ChAT) Polymorphism and Treatment Responses of Galantamine in Alzheimer's Disease Patients

Lee YM, Seo MK, Kim DK

  • J Korean Geriatr Psychiatry.
  • 2008 Jun;12(1):28-33.
Cholineacetyltrasnferase (ChAT) is a key enzyme that facilitates synthesis of acetylcholine affecting the memory, learning, awakening and sleep process of the cerebrum. The object of this study was to test...
Update Treatment of Dementia: Focus on Pharmacologic Treatment

Lee KJ

  • J Korean Geriatr Psychiatry.
  • 2008 Jun;12(1):17-27.
Dementia is an increasingly common diagnosis in our population, and the numbers are expected to rise exponentially in coming years. Within the past decades research has progressed rapidly on multiple...
Early Diagnosis of Alzheimer's Disease Using Neuroimaging: Focus on Recent MRI and PET Studies

Choo IH

  • J Korean Geriatr Psychiatry.
  • 2008 Jun;12(1):11-16.
Alzheimer's disease (AD) is the most common form of dementia. Because any antidementia treatment is not likely to reverse existing neuronal damage but rather to slow disease progression, early diagnosis...
The Conceptual History of Dementia and Alzheimer's Disease: Focus on Alzheimer's Disease

Kim SG, Jung HY

  • J Korean Geriatr Psychiatry.
  • 2008 Jun;12(1):3-10.
Most histories of senile dementia begin with Alois Alzheimer's description in 1906 of the first case of Alzheimer's disease. However, the history of senile dementia is quite rich, dating back...

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