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Major clinical research advances in gynecologic cancer in 2010

Suh DH, Kim JW, Kim K, Kang SB

This review summarizes 11 major clinical research advances in gynecologic oncology in 2010. For ovarian cancer, bevacizumab as a leading molecular targeted agent, pegylated liposomal doxorubicin in recurrent disease, the...
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Prediction and prevention of preterm birth after cervical conization

Lee SM, Jun JK

No abstract available.
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Sarcoma botryoides (embryonal rhabdomyosarcoma) of the uterine cervix in sisters

Mousavi A, Akhavan S

Sarcoma botryoides (embryonal rhabdomyosarcoma) rarely arises in the uterine cervix. We report a case of a 14-year-old female with sarcoma botryoides who presented with prolonged vaginal bleeding and cervical polyp....
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Outcomes of advanced and recurrent cervical cancer treated with cisplatin and generic topotecan: retrospective analysis in a tertiary care hospital in Thailand

Suprasert , Charoenkwan K, Cheewakriangkrai C

OBJECTIVE: Retrospective evaluation of the outcome of stage IVB, recurrent or persistent cervical cancer treated with cisplatin and generic topotecan (CT) in a tertiary care hospital in Thailand. METHODS: The medical...
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Combined open surgical and endovascular management of ruptured femoral artery from recurrent vulvar cancer

Trompetas , Sandison A, Anderson H

We report on the case of a 50-year-old woman with exsanguinating haemorrhage from the common femoral artery as a complication of recurrent vulvar cancer in the groin which was managed...
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The twenty-first century role of Piver-Rutledge type III radical hysterectomy and FIGO stage IA, IB1, and IB2 cervical cancer in the era of robotic surgery: a personal perspective

Piver MS, Ghomi A

Type III radical hysterectomy reported in 1974 by Piver, Rutledge, and Smith is considered worldwide by many as the standard surgical therapy for invasive cervical carcinoma stage IB and IIA....
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Epidemiological characteristics of ovarian cancer in Korea

Park B, Park S, Kim TJ, Ma SH, Kim BG, Kim YM, Kim JW, Kang S, Kim J, Kim TJ, Yoo KY, Park SK

OBJECTIVE: This study was conducted to examine recent trends in ovarian cancer incidence and mortality and secular trends in demographic factors in Korea. METHODS: With the data from Korea Central Cancer...
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Comparison of total plasma lysophosphatidic acid and serum CA-125 as a tumor marker in the diagnosis and follow-up of patients with epithelial ovarian cancer

Bese T, Barbaros M, Baykara E, Guralp O, Cengiz S, Demirkiran F, Sanioglu C, Arvas M

OBJECTIVE: To evaluate the role of lysophosphatidic acid (LPA) as a tumor marker in diagnosis and follow-up of patients with epithelial ovarian cancer. METHODS: Eighty-seven epithelial ovarian cancer patients, 74 benign...
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Endometrial mullerian adenosarcoma after toremifene treatment in breast cancer patients: a case report

Chung YW, Bae HS, Han SI, Song JY, Kim IS, Kang JS

Toremifene is an anti-estrogen which has been shown to be effective in the treatment of breast cancer, and is thought to be a less uterotrophic agent than tamoxifen. The risk...
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The role of prophylactic cerclage in preventing preterm delivery after electrosurgical conization

Shin MY, Seo ES, Choi SJ, Oh SY, Kim BG, Bae DS, Kim JH, Roh CR

OBJECTIVE: To evaluate pregnancy outcomes after electrosurgical conization. METHODS: We retrospectively analyzed the outcomes of 56 singleton pregnancies after electrosurgical conization of the uterine cervix. Of the 56 cases, 25 women...
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Apoptosis-related mRNA expression profiles of ovarian cancer cell lines following cisplatin treatment

Yoon J, Kim ES, Lee SJ, Park CW, Cha HJ, Hong BH, Choi KY

OBJECTIVE: The aim of this study was to identify apoptosis-related genes of ovarian cancer cell lines following cisplatin treatment. METHODS: We used IC50 values and fluorescence-activated cell sorting analysis to compare...
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Pregnancy outcome after cervical conization: risk factors for preterm delivery and the efficacy of prophylactic cerclage

Nam KH, Kwon JY, Kim YH, Park YW

OBJECTIVE: This study examined the risk factors for preterm birth and the efficacy of prophylactic cerclage in patients who had undergone cervical conization due to cervical intraepithelial neoplasia before pregnancy. METHODS:...
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The effect of combined treatment with cisplatin and histone deacetylase inhibitors on HeLa cells

Jin KL, Park JY, Noh EJ, Hoe KL, Lee JH, Kim JH, Nam JH

OBJECTIVE: To investigate the combined effects of cisplatin and the histone deacetylase (HDAC) inhibitors suberoylanilide hydroxamic acid (SAHA) or sirtinol on HeLa cells and assess the mechanism underlying HDAC inhibitor-cisplatin...
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