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Polymorphism Located in the Upstream Region of the RPS19 Gene (rs2305809) Is Associated With Cervical Cancer: A Case-control Study

da Rocha Boeira T, Coser J, Wolf JM, Cardinal B, Grivicich , Simon D, Lunge VR

  • J Cancer Prev.
  • 2018 Sep;23(3):147-152.
  • doi: 10.15430/JCP.2018.23.3.147
Cervical cancer (CC) is caused by persistent human papillomavirus (HPV) infection and affects women worldwide. The progression of an HPV persistent infection to CC is influenced by genetic factors. Three...
Proteases are Modulated by Fascin in Oral Cancer Invasion

Lee MK, Park JH, Gi SH, Hwang YS

  • J Cancer Prev.
  • 2018 Sep;23(3):141-146.
  • doi: 10.15430/JCP.2018.23.3.141
BACKGROUND: Cancer invasion is a critical factor for survival and prognosis of patients with cancer. Identifying and targeting factors that influence cancer invasion are an important strategy to overcome cancer....
Diallyl Trisulfide Suppresses the Production of Lipopolysaccharide-induced Inflammatory Mediators in BV2 Microglia by Decreasing the NF-κB Pathway Activity Associated With Toll-like Receptor 4 and CXCL12/CXCR4 Pathway Blockade

Lee HH, Jeong JW, Hong SH, Park C, Kim BW, Choi YH

  • J Cancer Prev.
  • 2018 Sep;23(3):134-140.
  • doi: 10.15430/JCP.2018.23.3.134
BACKGROUND: Diallyl trisulfide (DATS), a garlic-derived organosulfuric compound, has been documented for potential anti-inflammatory effects. However, the mechanism in microglia remains unknown. In this study, we investigated the anti-inflammatory effects...
Application of the Adverse Outcome Pathway Framework to Risk Assessment for Predicting Carcinogenicity of Chemicals

Kang DS, Yang JH, Kim HS, Koo BK, Lee CM, Ahn YS, Jung JH, Seo YR

  • J Cancer Prev.
  • 2018 Sep;23(3):126-133.
  • doi: 10.15430/JCP.2018.23.3.126
As industry develops in modern society, many chemicals are being used. The safety of chemicals is an important issue because humans are constantly exposed to chemicals throughout their daily life....
The Effect of Microbiota on Colon Carcinogenesis

Yoon K, Kim N

  • J Cancer Prev.
  • 2018 Sep;23(3):117-125.
  • doi: 10.15430/JCP.2018.23.3.117
Although genetic background is known to contribute to colon carcinogenesis, the exact etiology of the disease remains elusive. The organ’s extensive interaction with microbes necessitated research on the role of...
PIM Kinase as an Executional Target in Cancer

Zhang X, Song M, Kundu JK, Lee MH, Liu ZZ

  • J Cancer Prev.
  • 2018 Sep;23(3):109-116.
  • doi: 10.15430/JCP.2018.23.3.109
PIM (proviral integration site for moloney murine leukemia virus) kinase plays a key role as an oncogene in various cancers including myeloma, leukemia, prostate and breast cancers. The aberrant expression...

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