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Isoliquiritigenin Inhibits Metastatic Breast Cancer Cell-induced Receptor Activator of Nuclear Factor Kappa-B Ligand/Osteoprotegerin Ratio in Human Osteoblastic Cells

Lee SK, Park KK, Kim KR, Kim HJ, Chung WY

  • J Cancer Prev.
  • 2015 Dec;20(4):281-286.
  • doi: 10.15430/JCP.2015.20.4.281
Bone destruction induced by the metastasis of breast cancer cells is a frequent complication that is caused by the interaction between cancer cells and bone cells. Receptor activator of nuclear...
Evaluation and Comparison of the Biopathology of Collagen and Inflammation in the Extracellular Matrix of Oral Epithelial Dysplasias and Inflammatory Fibrous Hyperplasia Using Picrosirius Red Stain and Polarising Microscopy: A Preliminary Study

Varghese S, Sarojini S, George GB, Vinod S, Mathew P, Babu A, Sebastian

  • J Cancer Prev.
  • 2015 Dec;20(4):275-280.
  • doi: 10.15430/JCP.2015.20.4.275
BACKGROUND: The role of tumour inflammation and the dysplastic epithelial-stromal interactions on the nature of collagen fibres in the extracellular matrix of dysplastic epithelium is not fully understood. The present...
The Significance of miR-34a Expression in Endometrial Carcinogenesis: Correlation With Expression of p16 and Ki-67 Proteins in Endometrial Cancers

Choi YS, Lee KE

  • J Cancer Prev.
  • 2015 Dec;20(4):268-274.
  • doi: 10.15430/JCP.2015.20.4.268
BACKGROUND: A microRNA, miR-34a, plays a key role in inhibiting cellular transformation and carcinogenesis by controlling cell cycle regulation and cell proliferation in various human tumors. However, miR-34a has rarely...
Adequate Dextran Sodium Sulfate-induced Colitis Model in Mice and Effective Outcome Measurement Method

Park YH, Kim N, Shim YK, Choi YJ, Nam RH, Choi YJ, Ham MH, Suh JH, Lee SM, Lee CM, Yoon H, Lee HS, Lee DH

  • J Cancer Prev.
  • 2015 Dec;20(4):260-267.
  • doi: 10.15430/JCP.2015.20.4.260
BACKGROUND: Dextran sodium sulfate (DSS)-induced colitis mouse model is used for research of inflammatory bowel disease. The aim of this study was to establish the adequate conditions for DSS mice...
Selective Activator of the Glucocorticoid Receptor Compound A Dissociates Therapeutic and Atrophogenic Effects of Glucocorticoid Receptor Signaling in Skin

Klopot A, Baida G, Bhalla P, Haegeman G, Budunova I

  • J Cancer Prev.
  • 2015 Dec;20(4):250-259.
  • doi: 10.15430/JCP.2015.20.4.250
BACKGROUND: Glucocorticoids are effective anti-inflammatory drugs widely used in dermatology and for the treatment of blood cancer patients. Unfortunately, chronic treatment with glucocorticoids results in serious metabolic and atrophogenic adverse...
Anti-cancer Activity of Osmanthus matsumuranus Extract by Inducing G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma Hep G2 Cells

Jin S, Park HJ, Oh YN, Kwon HJ, Kim JH, Choi YH, Kim BW

  • J Cancer Prev.
  • 2015 Dec;20(4):241-249.
  • doi: 10.15430/JCP.2015.20.4.241
BACKGROUND: Osmanthus matsumuranus, a species of Oleaceae, is found in East Asia and Southeast Asia. The bioactivities of O. matsumuranus have not yet been fully understood. Here, we studied on...
An Overview of Carcinogenic Heavy Metal: Molecular Toxicity Mechanism and Prevention

Kim HS, Kim YJ, Seo YR

  • J Cancer Prev.
  • 2015 Dec;20(4):232-240.
  • doi: 10.15430/JCP.2015.20.4.232
Almost all heavy metals are serious toxicants as carcinogens. However, due to their chemical and physiological properties, heavy metals are useful in industrial areas including alloy, smelting and production of...
Natural Products for Chemoprevention of Breast Cancer

Ko EY, Moon A

  • J Cancer Prev.
  • 2015 Dec;20(4):223-231.
  • doi: 10.15430/JCP.2015.20.4.223
Breast cancer is the primary cause of cancer death in women. Although current therapies have shown some promise against breast cancer, there is still no effective cure for the majority...

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