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Trans-differentiation via Epigenetics: A New Paradigm in the Bone Regeneration

Cho YD, Ryoo HM

In regenerative medicine, growing cells or tissues in the laboratory is necessary when damaged cells can not heal by themselves. Acquisition of the required cells from the patient's own cells...
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The Effect of Antidepressants on Mesenchymal Stem Cell Differentiation

Kruk JS, Bermeo S, Skarratt K, Fuller SJ, Duque G

BACKGROUND: Use of antidepressant medications has been linked to detrimental impacts on bone mineral density and osteoporosis; however, the cellular basis behind these observations remains poorly understood. The effect does...
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α-Tocopheryl Succinate Inhibits Osteolytic Bone Metastasis of Breast Cancer by Suppressing Migration of Cancer Cells and Receptor Activator of Nuclear Factor-κB Ligand Expression of Osteoblasts

Kim B, Kim HH, Lee ZH

BACKGROUND: Breast cancer is one of the most common cancers affecting women and has a high incidence of bone metastasis, causing osteolytic lesions. The elevated expression of receptor activator of...
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Track and Field Practice and Bone Outcomes among Adolescents: A Pilot Study (ABCD-Growth Study)

Faustino-da-Silva YdSV, Agostinete RR, Werneck AO, Maillane-Vanegas S, Lynch KR, Exupério , Ito IH, Fernandes

BACKGROUND: Osteoporosis is considered a public health problem with high worldwide prevalence. One approach to prevention is through the promotion of physical activity, especially exercise, during adolescence. METHODS: This study compared...
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Review of Epidemiology, Diagnosis, and Treatment of Osteosarcopenia in Korea

Yoo JI, Ha YC

Sarcopenia was listed in the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) as M62.84, on October 1, 2016. Sarcopenia is primarily associated with metabolic diseases, such as diabetes,...
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New Skeletal Muscle Mass Index in Diagnosis of Sarcopenia

Moon JJ, Park SG, Ryu SM, Park CH

BACKGROUND: We sought to develop a novel index based on the skeletal muscle mass that reflects the change of quality of life (QOL), and is the most appropriate index for...
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Sarcopenic Obesity in Elderly Korean Women: A Nationwide Cross-sectional Study

Kwon YN, Yoon SS, Lee KH

BACKGROUND: Sarcopenia causes loss of muscle mass in the elderly and is associated with development of metabolic syndrome in those with obesity. This study evaluated the prevalence of sarcopenic obesity...
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Prevalence and Associated Risk Factors of Sarcopenia in Female Patients with Osteoporotic Fracture

Yoon BH, Lee JK, Choi DS, Han SH

BACKGROUND: We determined the prevalence of sarcopenia according to fracture site and evaluated the associated risk factors in female patients with osteoporotic fractures. METHODS: A total of 108 patients aged 50...
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