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Mutiple Spontaneous Rib Fractures in Patient with Cushing's Syndrome

Lee HJ, Je JH, Seo JH, Na YJ, Yoo HJ

Glucocorticoid (GC) excess, including Cushing's syndrome, is a common cause of secondary osteoporosis. Thirty to fifty percent of Cushing's syndrome patients experience non-traumatic fractures, which is often the presenting manifestation...
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Assessing Bone Quality in Terms of Bone Mineral Density, Buckling Ratio and Critical Fracture Load

Anitha D, Lee T

BACKGROUND: Bone mineral density (BMD) is used as a sole parameter in the diagnosis of osteoporosis. Due to the ease of acquirement of BMD, clinical diagnosis still involves its usage...
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Regulation of NFATc1 in Osteoclast Differentiation

Kim JH, Kim N

Osteoclasts are unique cells that degrade the bone matrix. These large multinucleated cells differentiate from the monocyte/macrophage lineage upon stimulation by two essential cytokines, macrophage colony-stimulating factor (M-CSF) and receptor...
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A Latent Autoimmune Diabetes in Adults Patient Manifesting Severe Musculoskeletal Complications

Yang IH, Lee SH, Chin SO, Chon S

Patients with diabetes have many different kinds of complications involving multiple organs, but those involving the musculoskeletal system are relatively uncommon. Diabetic muscle infarction (DMI) is a rare, painful, and...
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Undertreatment of Osteoporosis Following Hip Fractures in Jeju Cohort Study

Kim SR, Park YG, Kang SY, Nam KW, Park YG, Ha YC

BACKGROUND: Osteoporosis treatment following hip fracture is well known to not enough. We previously performed intervention study for orthopaedic surgeon's education and reported twofold increase in osteoporosis detection and treatment...
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Effect of Zoledronate on the Expression of Vascular Endothelial Growth Factor-A by Articular Chondrocytes and Synovial Cells: An in Vitro Study

Yi JW, Lee WS, Kim SB, Heo YM, Chae DS

BACKGROUND: The aim of this in vitro study was to determine the effect of zoledronate, which is frequently used to treat osteoporosis, on osteoarthritis by analyzing zoledronate-induced expression of vascular...
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Vitamin D Status and Response to Initial Vitamin D Supplementation in Korean Women with Osteoporosis

Kim JJ, Kim SS, Yoon SJ, Jung JG, Kim JS

BACKGROUND: The aim of this study is to evaluate whether the optimal vitamin D level is achieved after taking recommended dose in vitamin D deficient patients. METHODS: This was a retrospective...
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Methanol Extract of Croton Pycnanthus Benth. Inhibits Osteoclast Differentiation by Suppressing the MAPK and NF-kappaB Signaling Pathways

Lee J, Kim HH

BACKGROUND: Osteoclasts are differentiated from monocytes/macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-kappa B (NF-kappaB) ligand (RANKL). Croton pycnanthus Benth. (CPB) is a herbal plant that belongs to...
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