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Activation of Innate Immune System During Viral Infection: Role of Pattern-recognition Receptors (PRRs) in Viral Infection

Jun EJ, Kim YK

Innate immunity and adaptive immunity are two major immune responses against pathogens. Innate immunity is responsible for the immediate immune response to pathogens. Pattern-recognition receptors (PRRs) play an important role...
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Dissemination of Plasmid-mediated qnr, aac(6')-Ib-cr, and qepA Genes Among 16S rRNA Methylase Producing Enterobacteriaceae in Korea

Kang HY, Tamang MD, Seol SY, Kim J

Plasmid-mediated quinolone resistance (PMQR) genes: qnr, aac(6')-Ib-cr, and qepA were investigated among 153 armA and 51 rmtB-positive transconjugants and their 204 clinical isolates of Enterobacteriaceae. Overall, qnrB4 and aac(6')-Ib-cr genes...
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Epidemiological Analysis of Shiga Toxin-producing E. coli Isolated in Gwangju, Korea, by Pulse-field Gel Electrophoresis

Lee JC, Kim MJ

In Gwangju, Korea, over the last 4 years, human gastrointestinal infection caused by shiga toxin-producing E. coli (STEC) increased. The aim of this study was to ascertain the genetic relatedness...
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Molecular Identification of Clinical Rothia Isolates from Human Patients: Proposal of a Novel Rothia Species, Rothia arfidiae sp. nov.

Ko KS, Lee MY, Park YK, Peck KR, Song JH

Four Gram-positive cocci were isolated from the cerebrospinal fluid or blood of four different patients, but they could not be identified by an automated conventional identification system, so they were...
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In vitro Expansion of Natural Regulatory T Lymphocytes Useful for Cell Therapy in Allotransplantation

Park YH, Koo SK, Lee YJ, Joe IY, Kim SC, Han DJ, Lim DG

Immunotherapy with regulatory T lymphocytes is considered to be an attractive new therapeutic modality to prevent allograft rejection. The success of this new therapy is critically dependent on the preparation...
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Genetic Analysis of Hepatitis A Virus Isolated from Korea

Lee KO, Jeong SJ, Seong HS, Kim KT, Hwang YS, Kim GY, Lee SH

Hepatitis A virus (HAV) is one of the most important causes of acute infectious hepatitis. The aim of this study was to determine the genotypes of HAV that have been...
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Molecular Epidemiological Characteristics of Vibrio parahaemolyticus Isolated from Diarrheal Patients in Jeonnam, Korea

Jeon DY, Lee JC, Song HJ

To investigate the occurrence and distribution of serotype, specific virulence genes, and pulse field gel electrophoresis (PFGE) patterns in Vibrio parahaemolyticus isolates from Jeonnam, Korea, we tested 87 strains which...
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Expression of Endothelin-1 by Stimulation with CXCL8 in Mouse Peritoneal Macrophages

Bae JJ, Kim JH, Kim H, Kim HS

Endothelin-1 (ET-1) has been characterized as a potent vasoconstrictor secreted by the endothelium, and play a major role in the regulation of vascular tone. It has been also known to...
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Characterization of Immune Responses to Mycobacterium tuberculosis Rv2041c Protein

Kim SY, Shin AR, Lee BS, Kim HJ, Jeon BY, Cho SN, Park JK, Shin SJ

Tuberculosis, which is caused by Mycobacterium tuberculosis (M. tb), is one of the most important infectious diseases in the world. Although many functional studies have been conducted on M. tb...
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