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Influence of Physicochemical Environmental Factors on the Occurrence of Waterborne Viruses in Korean Surface Water

Lee G, Jee Y, Lee C, Lee S

In order to survey the occurrence of waterborne viruses in Korean surface water, a total of 192 water samples from July 2003 to January 2006 were collected and analyzed. The...
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Comparison of Consensus Sequences and Ancestor Sequences of HIV-1 nef and vif Genes for Development of Korean-Specfic HIV-1 Vaccine

Park CS, Kim MS, Yi HA, Lee KM, Kim SS, Lee SD, Lee CH

There have been attempts to use consensus sequences or ancestor sequences for development vaccines against viruses with high diversity and variation. In this study, we generated and compared consensus sequences...
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Expression and Packaging of a Human Endogenous Retrovirus-K Genomic DNA Clone

Ha-Lee YM

Human contains large number of human endogenous retroviruses (HERVs) in its genome. One of the HERV families, HERV-K, entered human genome most recently and includes many members with full-length intact...
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Development of a Mass Production Method of Platelet Activating Factor Acetylhydrolase

Jong YH, Chang HW, Lee TY

Platelet activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a potent lipid mediator in a variety of physiological events. PAF is also involved in various pathological events including allergy and inflammation. PAF-acetylhydrolase (PAF-AH)...
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Determination of Porcine Rotavirus Serotypes by RT-PCR and RFLP Analysis

Min HG, Lim YH, Kang SY

G and P tying of group A porcine rotaviruses (P(o)RV) from field fecal samples were performed using reversetranscriptase polymerization chain reaction (RT-PCR) and restriction fragment length polymorphism (RFLP) analysis. After...
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Spectrin Cleavage Induced by LLP-1 Lentivirus Lytic Peptide Domain in the Intracytoplasmic Tail of Human Immunodeficiency Virus Type 1 GP41 in Rat Organotypic Hippocampal Slice Cultures

Lee JH, Lee EO, Chong YH

We previously demonstrated that the lentivirus lytic peptide 1 (LLP-1) corresponding to the carboxyl terminus of HIV-1 gp41 induced cell death in human neuronal cells. Present study was conducted to...
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Complete Nucleotide Sequence of Genomic RNA of a Large-Plaque Forming Porcine Reproductive and Respiratory Syndrome Virus PL97-1/LP1

Lee YM

Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important animal pathogens in swine industry worldwide. In this study, we isolated the large-plaque forming variant virus designated...
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Purification of Native Ag85 Complex, 38-kDa and MTB12 Protein Antigens from the Culture Filtrate of Mycobacterium tuberculosis

Lee JS, Paik TH, Yoo YC, Lee J, Shin A, Song CH, Jo EK, Kim HJ, Park JK

The purification of immunodominant native protein antigens from the culture filtrates of Mycobacterium tuberculosis is needed for the development of new vaccines and immunodiagnostic reagents against tuberculosis. In the present...
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Detection and Quantification of Residual Cellular DNA in the Production of Recombinant HPV-16 L1 Virus-Like Particles

Son HK, Jeong HS, Kim YL, Kim SN, Shin JH, Min HK, Seong BL, Park SN

A number of recombinant proteins isolated from cell sources are being produced for biopharmaceuticals. Although most biopharmaceuticals are highly purified, there is a safety concern that such recombinant products could...
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Comparison of Biological and Genetic Characteristics Between Sucrose-Fermenting and Sucrose-Nonfermenting Vibrio vulnificus Isolates

Kim SM, So HA, Song KM, Lee YY, Lim CW, Lee JH, So HS, Kim JK, Park RK, Park SD

Twelve strains of V. vulnificus isolated from clinical specimens in 2002~2004 in Jeollado province were determined for their biologic groups, serotypes, presence of vvhA (hemolysin/cytolysin) gene, DNA sequence, and PFGE...
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Seroepidemiological Characteristics of Haemorrhagic Fever with Renal Syndrome from 1996 to 2005 in Korea

Noh YT, Cho JE, Han MG, Lee NY, Kim SY, Chu C, Lee HD, Nam JH, Park KY, Shin YH, Cho HW, Song HJ, Ju YR

Haemorrhagic fever with renal syndrome (HFRS) caused by Hantaan viruses has been one of the principal acute febrile disease in Korea. To analysis the sero-epidemiological patterns of HFRS, 4,177 patient...
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