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Cloning and Expression of Low Molecule Protein Antigens from Mycobacterium tuberculosis H37Rv

Lim JH, Kim HJ, Jo EK, Song CH, Kim UO, Park JK

  • KMID: 2099367
  • J Korean Soc Microbiol.
  • 2000 Oct;35(5):375-375.
No Abstract Available.
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Characterization of a Point Mutation in the First Intron of Bruton's Tyrosine Kinase ( Btk ) Gene

Jo EK, Song CH, Song YJ, Min DL, Kim HJ, Lim K, Shong MH, Lee JH, Kim JS, Park JK

  • KMID: 1646429
  • Korean J Immunol.
  • 2000 Dec;22(4):197-205.
No abstract available.
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Increased IL-12 and Interferon-Hamma, But Not IL-18 Production, After In Vitro Stimulation with a 30-kDa Mycobacterial Antigen in Patients with Tuberculous Pleurisy

Song CH, Jo EK, Kim HJ, Lim JH, Kim UO, Paik TH, Suhr JW, Park JK

  • KMID: 2099350
  • J Korean Soc Microbiol.
  • 2000 Oct;35(5):358-358.
No Abstract Available.
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IL-12 and TNF-alpha productions from human peripheral blood mononuclear cells in untreated patients with active pulmonary tuberculosis stimulated with 30-kDa or TSP antigen of Mycobacterium tuberculosis H37Rv

Song CH, Jo EK, Kim DS, Kim HJ, Lim JH, Kim UO, Paik TH, Park JK

No abstract available.
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Host-Pathogen Interactions Operative during Mycobacteroides abscessus Infection

Park EJ, Silwal P, Jo EK

Mycobacteroides abscessus (previously Mycobacteroides abscessus; Mabc), one of rapidly growing nontuberculous mycobacteria (NTM), is an important pathogen of NTM pulmonary diseases (NTM-PDs) in both immunocompetent and immunocompromised individuals. Mabc infection...
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Toll-like Receptors and Innate Immunity

Yuk JM, Jo EK

Toll-like receptors (TLRs) are the best-characterized membrane-bound receptors in innate immune cells, including macrophages and dendritic cells. Upon recognition of specific ligands originating from pathogen- and modified self-derived molecules, TLRs...
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Host-Pathogen Dialogues in Autophagy, Apoptosis, and Necrosis during Mycobacterial Infection

Kim JK, Silwal P, Jo EK

Mycobacterium tuberculosis (Mtb) is an etiologic pathogen of human tuberculosis (TB), a serious infectious disease with high morbidity and mortality. In addition, the threat of drug resistance in anti-TB therapy...
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Autophagy and bacterial infectious diseases

Yuk JM, Yoshimori , Jo EK

Autophagy is a housekeeping process that maintains cellular homeostasis through recycling of nutrients and degradation of damaged or aged cytoplasmic constituents. Over the past several years, accumulating evidence has suggested...
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The Role of Nitric Oxide in Mycobacterial Infections

Yang CS, Yuk JM, Jo EK

Although tuberculosis poses a significant health threat to the global population, it is a challenge to develop new and effective therapeutic strategies. Nitric oxide (NO) and inducible NO synthase (iNOS)...
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The Roles of Chemokines in Immune Response to Mycobacterial Infection

Paik S, Yang M, Suh HW, Jo EK

Tuberculosis (TB), a global and deadly infectious disease caused by Mycobacterium tuberculosis (Mtb), is manifested with host immune reaction. The balanced regulation between protective immune and pathologic inflammatory responses is...
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Host immune responses to mycobacterial antigens and their implications for the development of a vaccine to control tuberculosis

Yuk JM, Jo EK

Tuberculosis (TB) remains a worldwide health problem, causing around 2 million deaths per year. Despite the bacillus Calmette Guerin vaccine being available for more than 80 years, it has limited...
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The Role of NLR-related Protein 3 Inflammasome in Host Defense and Inflammatory Diseases

Yang CS, Shin DM, Jo EK

  • KMID: 2172999
  • Int Neurourol J.
  • 2012 Mar;16(1):2-12.
Among a number of innate receptors, the nucleotide-binding domain leucine-rich repeat containing (NLR) nucleotide oligomerization domain (NOD)-like receptor families are involved in the recognition of cytosolic pathogen- or danger-associated molecules....
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Spatial Distribution of Diabetes Prevalence Rates and Its Relationship with the Regional Characteristics

Jo EK, Seo EW, Lee KS

This study purposed to analyze the relationship between spatial distribution of Diabetes prevalence rates and regional variables. The unit of analysis was administrative districts of city·gun·gu. Dependent variable was the...
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Antimicrobial Peptides in Innate Immunity against Mycobacteria

Shin DM, Jo EK

Antimicrobial peptides/proteins are ancient and naturallyoccurring antibiotics in innate immune responses in a variety of organisms. Additionally, these peptides have been recognized as important signaling molecules in regulation of both...
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Identification of Proteins Induced at Hypoxic and Low pH Conditions in Mycobacterium tuberculosis H37Rv

Lee KS, Park JK, Lim JH, Kim SY, Shin AR, Yang CS, Oh JH, Kwon YM, Song CH, Jo EK, Kim HJ

Mycobacterium tuberculosis likely reside within a granuloma as a dormant state. An area of necrosis forms at the center of lung granulomas. Within this area, the bacteria are deprived of...
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A case of laparoscopic treatment of the retroperitoneal ectopic pregnancy

Park BR, Lee NH, Ann CO, Shim HJ, Jo EK, Kim YS, Bae DH

Ectopic pregnancy accounts for approximately 2% of all pregnancies and is the most common cause of pregnancy-related mortality in the first trimester. Initial evaluation consists of beta-hCG and pelvic ultrasonography....
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Determination of Anti-tuberculous Antibody Against Triton X-100 Solubilized Protein ( TSP ) Antigen of Mycobacterium tuberculosis in the Sera of Patients with Pulmonary Tuberculosis

Paik TH, Park JK, Kim HJ, Kim KJ, Jo EK

  • KMID: 2146949
  • J Korean Soc Microbiol.
  • 1997 Feb;32(1):59-70.
Some of the proteins of mycobacteria are preferentially associated with the cell wall and are powerful immunogens, and humoral antibody responses to these mycobacterial antigens may occur in patients with...
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CD40-CD40 Ligand Interactions in the Production of IL-12 and IFN-gamma by Tuberculous Pleural Mononuclear Cells

Song CH, Nam HH, An JO, Lee JS, Kim HJ, Park JK, Suhr JW, Jung SS, Na MJ, Paik TH, Jo EK

BACKGROUND: Our previous study showed that purified protein derivative (PPD)- stimulated pleural mononuclear cells (PMC) from tuberculous pleurisy (Tbp) produced significantly more IFN-gamma (10- to 70-fold) after in vitro PPD...
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A case of immature sacrococcygeal teratoma diagnosed by prenatal ultrasonography

Jo EK, Ann CO, Shim HJ, Kim YS, Bae DH, Yang SH, Lee JH

Sacrococcygeal teratoma (SCT) is a rare subset of germ cell neoplasm and occurs in approximately 1 in 35,000 live births. Most SCTs are benign, but about 20% are malignant. They...
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NLRP3 Inflammasome and Host Protection against Bacterial Infection

Kim JJ, Jo EK

The inflammasome is a multi-protein complex that induces maturation of inflammatory cytokines interleukin (IL)-1beta and IL-18 through activation of caspase-1. Several nucleotide binding oligomerization domain-like receptor family members, including NLRP3,...
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