- Effectiveness and Usefulness of Bone Turnover Marker in Osteoporosis Patients: A Multicenter Study in Korea
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Yoo JI, Park SY, Kim DY, Ha J, Rhee Y, Hong N, Kim JT, Yi HS, Kim BK, Lee YK, Ha YC, Jeon YK, Kim HY, Ahn SH, Hong S, Lee SY
- KMID: 2548586
- J Bone Metab.
- 2023 Nov;30(4):311-317.
- doi: 10.11005/jbm.2023.30.4.311
Background: This study aimed to investigate real-world data of C-terminal telopeptide (CTX), propeptide of type I collagen (P1NP), and osteocalcin through present multicenter clinical study, and retrospectively analyze the usefulness... -
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- Targeting CD73 to Overcomes Resistance to First-Generation EGFR Tyrosine Kinase Inhibitors in Non–Small Cell Lung Cancer
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Kim M, Kim S, Yim J, Keam B, Kim TM, Jeon YK, Kim DW, Heo DS
- KMID: 2547788
- Cancer Res Treat.
- 2023 Oct;55(4):1134-1143.
- doi: 10.4143/crt.2023.311
Purpose In patients with epidermal growth factor receptor (EGFR)-mutant non–small cell lung cancer (NSCLC), EGFR tyrosine kinase inhibitors (TKIs) improve response rate and survival. However, most patients eventually develop resistance.... -
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- Cancer-Specific Sequences in the Diagnosis and Treatment of NUT Carcinoma
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Lee MS, An S, Song JY, Sung M, Jung K, Chang ES, Choi J, Oh DY, Jeon YK, Yang H, Lakshmi C, Park S, Han J, Lee SH, Choi YL
- KMID: 2541232
- Cancer Res Treat.
- 2023 Apr;55(2):452-467.
- doi: 10.4143/crt.2022.910
Purpose NUT carcinoma (NC) is a solid tumor caused by the rearrangement of NUTM1 that usually develops in midline structures, such as the thorax. No standard treatment has been established... -
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- Trabecular Bone Score and Central Quantitative Computed Tomography for the Prediction of Vertebral Fragility Fractures in Postmenopausal Women
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Ryang S, Jeon YK, Goh TS, Kim IJ, Kim K
- KMID: 2540507
- J Bone Metab.
- 2023 Feb;30(1):77-86.
- doi: 10.11005/jbm.2023.30.1.77
Background: We aimed to investigate whether densitometry results and volumetric bone mineral density (vBMD) can predict vertebral fragility fractures (VFF) in postmenopausal women. Methods: We enrolled 271 postmenopausal women aged >45... -
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- Interlaboratory Comparison Study (Ring Test) of Next-Generation Sequencing–Based NTRK Fusion Detection in South Korea
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Lee SE, Lee MS, Jeon YK, Shim HS, Kang J, Kim J, Choi YL
- KMID: 2537989
- Cancer Res Treat.
- 2023 Jan;55(1):28-40.
- doi: 10.4143/crt.2021.1572
Purpose Tropomyosin receptor kinase (TRK) inhibitors are approved for the treatment of neurotrophic receptor tyrosine kinase (NTRK) fusion-positive tumors. The detection of NTRK fusion using a validated method is required... -
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- Protective effect of low-intensity treadmill exercise against acetylcholine-calcium chloride-induced atrial fibrillation in mice
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Sung DJ, Jeon YK, Choi J, Kim B, Golpasandi S, Park SW, Oh SB, Bae YM
- KMID: 2532761
- Korean J Physiol Pharmacol.
- 2022 Sep;26(5):313-323.
- doi: 10.4196/kjpp.2022.26.5.313
Atrial fibrillation (AF) is the most common supraventricular arrhythmia, and it corresponds highly with exercise intensity. Here, we induced AF in mice using acetylcholine (ACh)-CaCl2 for 7 days and aimed... -
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- Lymphoproliferative disorder involving body fluid: diagnostic approaches and roles of ancillary studies
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Koh J, Shin SA, Lee JA, Jeon YK
- KMID: 2531609
- J Pathol Transl Med.
- 2022 Jul;56(4):173-186.
- doi: 10.4132/jptm.2022.05.16
Lymphocyte-rich effusions represent benign reactive process or neoplastic condition. Involvement of lymphoproliferative disease in body cavity is not uncommon, and it often causes diagnostic challenge. In this review, we suggest... -
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- An unusual case of microsatellite instability–high/deficient mismatch repair (MSI-H/dMMR) diffuse large B-cell lymphoma revealed by targeted gene sequencing
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Han B, Kim S, Koh J, Bae JM, Yun H, Jeon YK
- KMID: 2527193
- J Pathol Transl Med.
- 2022 Mar;56(2):92-96.
- doi: 10.4132/jptm.2021.10.15
Microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR) status has been approved as a tissue-agnostic biomarker for immune checkpoint inhibitor therapy in patients with solid tumors. We report the case of an MSI-H/dMMR... -
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- Clinicopathologic implication of PD-L1 gene alteration in primary adrenal diffuse large B cell lymphoma
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Lee KR, Koh J, Jeon YK, Kwon HJ, Lee JO, Paik JH
- KMID: 2524227
- J Pathol Transl Med.
- 2022 Jan;56(1):32-39.
- doi: 10.4132/jptm.2021.10.05
Background: Primary adrenal (PA) diffuse large B cell lymphoma (DLBCL) was previously reported as an aggressive subset of DLBCL, but its genetic features were not sufficiently characterized. From our previous... -
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- Acquired Resistance Mechanism of EGFR Kinase Domain Duplication to EGFR TKIs in Non–Small Cell Lung Cancer
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Lee C, Kim M, Kim DW, Kim TM, Kim S, Im SW, Jeon YK, Keam B, Ku JL, Heo DS
- KMID: 2524595
- Cancer Res Treat.
- 2022 Jan;54(1):140-149.
- doi: 10.4143/crt.2021.385
Purpose Epidermal growth factor receptor kinase domain duplication (EGFR-KDD) is a rare and poorly understood oncogenic mutation in non–small cell lung cancer (NSCLC). We aimed to investigate the acquired resistance... -
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- Whole-Exome Sequencing in Papillary Microcarcinoma: Potential Early Biomarkers of Lateral Lymph Node Metastasis
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Kim M, Kwon CH, Jang MH, Kim JM, Kim EH, Jeon YK, Kim SS, Choi KU, Kim IJ, Park M, Kim BH
- KMID: 2521956
- Endocrinol Metab.
- 2021 Oct;36(5):1086-1094.
- doi: 10.3803/EnM.2021.1132
Background: Early identification of patients with high-risk papillary thyroid microcarcinoma (PTMC) that is likely to progress has become a critical challenge. We aimed to identify somatic mutations associated with lateral... -
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- Temporal evolution of programmed death-ligand 1 expression in patients with non-small cell lung cancer
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Nam CH, Koh J, Ock CY, Kim M, Keam B, Kim TM, Jeon YK, Kim DW, Chung DH, Heo DS
- KMID: 2517814
- Korean J Intern Med.
- 2021 Jul;36(4):975-984.
- doi: 10.3904/kjim.2020.178
Background/Aims: Programmed death-ligand 1 (PD-L1) expression, a validated predictive biomarker for anti-PD-1/PD-L1 inhibitors, is reported to change over time. This poses challenges during clinical application in non-small cell lung cancer. Methods:... -
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- A case of concomitant EGFR/ALK alteration against a mutated EGFR background in early-stage lung adenocarcinoma
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Lee KC, Koh J, Chung DH, Jeon YK
- KMID: 2513900
- J Pathol Transl Med.
- 2021 Mar;55(2):139-144.
- doi: 10.4132/jptm.2020.12.16
Rare cases of lung adenocarcinoma (LUAD) with concomitant epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) translocation have been reported. However, their clonal and evolutional relationship remains... -
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- Morphologic variant of follicular lymphoma reminiscent of hyaline-vascular Castleman disease
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Koh J, Jeon YK
- KMID: 2501661
- J Pathol Transl Med.
- 2020 May;54(3):253-257.
- doi: 10.4132/jptm.2019.12.17
Follicular lymphoma (FL) with hyaline-vascular Castleman disease (FL-HVCD)-like features is a rare morphologic variant, with fewer than 20 cases in the literature. Herein, we report a case of FL-HVCD in... -
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- Association between Serum Free Thyroxine and Anemia in Euthyroid Adults: A Nationwide Study
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Kim M, Kim BH, Lee H, Jang MH, Kim JM, Kim EH, Jeon YK, Kim SS, Kim IJ
- KMID: 2471726
- Endocrinol Metab.
- 2020 Mar;35(1):106-114.
- doi: 10.3803/EnM.2020.35.1.106
BACKGROUND: Studies on the relationship between thyroid function and anemia in the euthyroid range are scarce. We aimed to evaluate the association between anemia and serum free thyroxine (fT4) and... -
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- Combined Aerobic and Resistance Exercise Training Reduces Circulating Apolipoprotein J Levels and Improves Insulin Resistance in Postmenopausal Diabetic Women
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Jeon YK, Kim SS, Kim JH, Kim HJ, Kim HJ, Park JJ, Cho YS, Joung SH, Kim JR, Kim BH, Song SH, Kim IJ, Kim YK, Kim YB
- KMID: 2470959
- Diabetes Metab J.
- 2020 Feb;44(1):103-112.
- doi: 10.4093/dmj.2018.0160
BACKGROUND: Circulating apolipoprotein J (ApoJ) is closely associated with insulin resistance; however, the effect of exercise on circulating ApoJ levels and the association of ApoJ with metabolic indices remain unknown.... -
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- Analysis of interaction between intracellular spermine and transient receptor potential canonical 4 channel: multiple candidate sites of negatively charged amino acids for the inward rectification of transient receptor potential canonical 4
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Kim J, Moon SH, Kim T, Ko J, Jeon YK, Shin YC, Jeon JH, So I
- KMID: 2466574
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):101-110.
- doi: 10.4196/kjpp.2020.24.1.101
Transient receptor potential canonical 4 (TRPC4) channel is a nonselective calcium-permeable cation channels. In intestinal smooth muscle cells, TRPC4 currents contribute more than 80% to muscarinic cationic current (mIcat). With... -
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- The Relationship between Thyroid Function and Different Obesity Phenotypes in Korean Euthyroid Adults
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Kim JM, Kim BH, Lee H, Kim EH, Kim M, Kim JH, Jeon YK, Kim SS, Kim IJ, Kim YK
- KMID: 2466507
- Diabetes Metab J.
- 2019 Dec;43(6):867-878.
- doi: 10.4093/dmj.2018.0130
BACKGROUND: Thyroid disease and metabolic syndrome are both associated with cardiovascular disease. The aim of this study was to investigate the correlation between thyroid hormones and obesity sub-phenotypes using nationwide... -
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- Use of Bone Turnover Markers in Clinical Practice for the Management of Osteoporosis in Korea: From the Survey on the Prescription Pattern of Bone Turnover Markers
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Ahn SH, Park SY, Yoo JI, Chung YJ, Jeon YK, Yoon BH, Kim HY, Lee SH, Lee J, Hong S
- KMID: 2465029
- J Bone Metab.
- 2019 Nov;26(4):271-277.
- doi: 10.11005/jbm.2019.26.4.271
BACKGROUND: There has been interest in the clinical potential of bone turnover markers (BTMs) as tools both for assessing fracture risk and for monitoring treatment. However, the practical use of... -
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- Position Statement on the Use of Bone Turnover Markers for Osteoporosis Treatment
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Park SY, Ahn SH, Yoo JI, Chung YJ, Jeon YK, Yoon BH, Kim HY, Lee SH, Lee J, Hong S
- KMID: 2465023
- J Bone Metab.
- 2019 Nov;26(4):213-224.
- doi: 10.11005/jbm.2019.26.4.213
Current evidences continue to support the clinical application of bone turnover markers (BTMs) in the management of postmenopausal osteoporosis. The limitations of bone mineral density measured by dual energy X-ray... -
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