- XperCT-guided Intra-cisterna Magna Injection of Streptozotocin for Establishing an Alzheimer’s Disease Model Using the Cynomolgus Monkey (Macaca fascicularis)
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Park J, Won J, Jeon CY, Lim KS, Choi WS, Park Sh, Seo J, Cho J, Seong JB, Yeo HG, Kim K, Kim YG, Kim M, Yi KS, Lee Y
- KMID: 2537960
- Exp Neurobiol.
- 2022 Dec;31(6):409-418.
- doi: 10.5607/en22027
Till date, researchers have been developing animal models of Alzheimer’s disease (AD) in various species to understand the pathological characterization and molecular mechanistic pathways associated with this condition in humans... -
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- Sudden cardiac death as a naturally-occurring ventricular hypertrophy in Macaca fascicularis
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Yeo HG, Park J, Kim HK, Lee JM, Koo BS, An JH, Jeon CY, An YJ, Choi WS, Park SH, Seo J, Won J, Kim K, Cho J, Kim YG, Kim M, Seong JB, Huh JW, Kim SS, Lee Y, Lim KS
- KMID: 2528069
- J Biomed Transl Res.
- 2021 Sep;22(3):135-139.
- doi: 10.12729/jbtr.2021.22.3.135
Naturally occurring left ventricular hyperplasia is a rare but lethal disease. There are very few reports of this cardiac disease in captive nonhuman primates. In a colony of Macaca mulatta... -
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- Impaired Hand Dexterity Function in a Non-human Primate Model with Chronic Parkinson’s Disease
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Seo Jc, Won Jy, Kim Kw, Park Jh, Yeo HG, Kim YG, Baek SH, Lee H, Jeon CY, Choi WS, Lee S, Kim KJ, Park SH, Son Yh, Jeong KJ, Lim KS, Kang P, Lee HY, Son HC, Huh JW, Kim YH, Lee DS, Lee SR, Choi JW, Lee Yj
- KMID: 2508474
- Exp Neurobiol.
- 2020 Oct;29(5):376-388.
- doi: 10.5607/en20040
ymptoms of Parkinson’s disease (PD) caused by loss of dopaminergic neurons are accompanied by movement disorders, including tremors, rigidity, bradykinesia, and akinesia. Non-human primate (NHP) models with PD play an... -
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- Assessment of Hand Motor Function in a Non-human Primate Model of Ischemic Stroke
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Won J, Yi KS, Choi CH, Jeon CY, Seo J, Kim K, Yeo HG, Park J, Kim YG, Jin YB, Koo BS, Lim KS, Lee S, Kim KJ, Choi WS, Park SH, Kim YH, Huh JW, Lee SR, Cha SH, Lee Y
- KMID: 2506534
- Exp Neurobiol.
- 2020 Aug;29(4):300-313.
- doi: 10.5607/en20023
Ischemic stroke results from arterial occlusion and can cause irreversible brain injury. A non-human primate (NHP) model of ischemic stroke was previously developed to investigate its pathophysiology and for efficacy... -
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- Synaptic loss and amyloid beta alterations in the rodent hippocampus induced by streptozotocin injection into the cisterna magna
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Ahn Y, Seo J, Park J, Won J, Yeo HG, Kim K, Jeon CY, Huh JW, Lee SR, Lee DS, Lee Y
- KMID: 2506040
- Lab Anim Res.
- 2020 Jun;36(2):134-139.
- doi: 10.1186/s42826-020-00049-x
To date, researchers have developed various animal models of Alzheimer’s disease (AD) to investigate its mechanisms and to identify potential therapeutic treatments. A widely recognized model that mimics the pathology... -
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- Effect of dyslipidemia on vascular smooth muscle cell proliferation in a porcine coronary restenosis model
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Jeong KJ, Kang P, Lee HY, Son HC, Park SH, Choi WS, Koo BS, Jeon CY, Baek SH, An YJ, Kim HK, Kim SS, Park JK, Bae IH, Park DS, Shim JW, Kim JU, Kim NY, Kim SU, Lim KS, Jeong MH
- KMID: 2470312
- J Biomed Transl Res.
- 2019 Dec;20(4):91-98.
- doi: 10.12729/jbtr.2019.20.4.091
This study aimed to examine the effect of a mild elevation in serum cholesterol level in a porcine coronary overstretch restenosis model using a balloon angioplasty catheter or drug-eluting coronary... -
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- Increased CD68/TGFβ Co-expressing Microglia/Macrophages after Transient Middle Cerebral Artery Occlusion in Rhesus Monkeys
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Yeo HG, Hong JJ, Lee Y, Yi KS, Jeon CY, Park J, Won J, Seo J, Ahn YJ, Kim K, Baek SH, Hwang EH, Kim G, Jin YB, Jeong KJ, Koo BS, Kang P, Lim KS, Kim SU, Huh JW, Kim YH, Son Y, Kim JS, Choi CH, Cha SH, Lee SR
- KMID: 2458544
- Exp Neurobiol.
- 2019 Aug;28(4):458-473.
- doi: 10.5607/en.2019.28.4.458
The function of microglia/macrophages after ischemic stroke is poorly understood. This study examines the role of microglia/macrophages in the focal infarct area after transient middle cerebral artery occlusion (MCAO) in... -
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- Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson's Disease: Drp1 and CDK5/p25 Signaling
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Park J, Seo J, Won J, Yeo HG, Ahn YJ, Kim K, Jin YB, Koo BS, Lim KS, Jeong KJ, Kang P, Lee HY, Baek SH, Jeon CY, Hong JJ, Huh JW, Kim YH, Park SJ, Kim SU, Lee DS, Lee SR, Lee Y
- KMID: 2451076
- Exp Neurobiol.
- 2019 Jun;28(3):414-424.
- doi: 10.5607/en.2019.28.3.414
Mitochondria continuously fuse and divide to maintain homeostasis. An impairment in the balance between the fusion and fission processes can trigger mitochondrial dysfunction. Accumulating evidence suggests that mitochondrial dysfunction is... -
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- Evaluation of fecal microbiomes associated with obesity in captive cynomolgus monkeys (Macaca fascicularis)
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Koo BS, Hwang EH, Kim G, Oh H, Son Y, Lee D, Lim KS, Kang P, Lee S, Lee HY, Jeong KJ, Lee Y, Baek SH, Jeon CY, Park SJ, Kim YH, Huh JW, Jin YB, Kim SU, Lee SR, Hong JJ
- KMID: 2448703
- J Vet Sci.
- 2019 May;20(3):e19.
- doi: 10.4142/jvs.2019.20.e19
Microorganisms play important roles in obesity; however, the role of the gut microbiomes in obesity is controversial because of the inconsistent findings. This study investigated the gut microbiome communities in... -
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- Rise of the Visible Monkey: Sectioned Images of Rhesus Monkey
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Chung BS, Jeon CY, Huh JW, Jeong KJ, Har D, Kwack KS, Park JS
- KMID: 2441909
- J Korean Med Sci.
- 2019 Mar;34(8):e66.
- doi: 10.3346/jkms.2019.34.e66
BACKGROUND: Gross anatomy and sectional anatomy of a monkey should be known by students and researchers of veterinary medicine and medical research. However, materials to learn the anatomy of a... -
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- Complications of Allograft Reconstruction following Wide Resection of Malignant Bone Tumors in Long Bones
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Kim KJ, Lee SK, Jeon CY, Ma CH, Kim SM
- KMID: 2429175
- J Korean Orthop Assoc.
- 2018 Jun;53(3):264-270.
- doi: 10.4055/jkoa.2018.53.3.264
PURPOSE: We evaluated the results of allograft reconstruction following wide resection of malignant bone tumors in long bone, retrospectively. MATERIALS AND METHODS: Seven patients were included. The mean age was 44... -
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- The Thickness of Each Retinal Layer and Visual Acuity after Vitrectomy in Idiopathic Epiretinal Membrane
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Kim MH, Jeon CY, Baek SK, Chang YS, Lee YH
- KMID: 2376597
- J Korean Ophthalmol Soc.
- 2017 Apr;58(4):420-429.
- doi: 10.3341/jkos.2017.58.4.420
PURPOSE: In this study, we evaluated the thickness of each retinal layer using spectral-domain optical coherence tomography (OCT) and investigated the correlation between the thickness of each retinal layer and... -
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- Noninfectious Endophthalmitis after Intravitreal Injection of Aflibercept
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Kim CH, Shin JS, Jeon CY, Chang YS, Lee YH
- KMID: 2290509
- J Korean Ophthalmol Soc.
- 2016 Jun;57(6):1018-1021.
- doi: 10.3341/jkos.2016.57.6.1018
PURPOSE: To report a case of noninfectious endophthalmitis after intravitreal injection of aflibercept. CASE SUMMARY: A 67-year-old male patient presented with sudden vision loss 2 days after intravitreal aflibercept injection for... -
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- Two Cases of Young Patients with Bilateral Posterior Scleritis Accompanied with Serous Retinal Detachment
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Jeon CY, Kang HJ, Na SJ, Lee TG
- KMID: 2215261
- J Korean Ophthalmol Soc.
- 2012 Jan;53(1):168-174.
- doi: 10.3341/jkos.2012.53.1.168
PURPOSE: To report 2 young female patients with bilateral posterior scleritis and serous retinal detachment. CASE SUMMARY: An 11-year-old girl (Case 1) and a 16-year-old girl (Case 2) visited our clinic... -
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- The Clinical Outcomes of 23-Gauge Transconjunctival Sutureless Vitrectomy for Endophthalmitis after Cataract Surgery
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Jeon CY, Lee TG, Na SJ
- KMID: 2214998
- J Korean Ophthalmol Soc.
- 2011 Oct;52(10):1167-1172.
- doi: 10.3341/jkos.2011.52.10.1167
PURPOSE: To report the clinical outcomes and utility of 23-gauge (G) transconjunctival sutureless vitrectomy (TSV) in patients with postoperative endophthalmitis following cataract surgery. METHODS: The medical records of 16 patients (17... -
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- Visual Acuity and Astigmatism after Simultaneous Surgery for Upper and Lower Eyelid Epiblepharon in Children
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Hyun DW, Jeon CY, Jin SY, Ha MS
- KMID: 2214290
- J Korean Ophthalmol Soc.
- 2011 Mar;52(3):272-276.
- doi: 10.3341/jkos.2011.52.3.272
PURPOSE: To study the changes in vision and astigmatism in epiblepharon patients undergoing simultaneous surgery for both upper and lower eyelid epiblepharon. METHODS: The study subjects consisted of 40 eyes of... -
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- p190RhoGAP and Rap-dependent RhoGAP (ARAP3) inactivate RhoA in response to nerve growth factor leading to neurite outgrowth from PC12 cells
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Jeon CY, Kim HJ, Lee JY, Kim J, Kim SC, Park JB
- KMID: 946633
- Exp Mol Med.
- 2010 May;42(5):335-344.
- doi: 10.3858/emm.2010.42.5.035
Rat pheochromocytoma (PC12) cells have been used to investigate neurite outgrowth. Nerve growth factor (NGF) has been well known to induce neurite outgrowth from PC12 cells. RhoA belongs to Ras-related... -
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- Downstream components of RhoA required for signal pathway of superoxide formation during phagocytosis of serum opsonized zymosans in macrophages
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Kim JS, Kim JG, Jeon CY, Won HY, Moon MY, Seo JY, Kim JI, Kim J, Lee JY, Choi SY, Park J, Yoon Park , Ha KS, Kim PH, Park JB
- KMID: 1116203
- Exp Mol Med.
- 2005 Dec;37(6):575-587.
Rac1 and Rac2 are essential for the control of oxidative burst catalyzed by NADPH oxidase. It was also documented that Rho is associated with the superoxide burst reaction during phagocytosis... -
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- Sudden Cardiac Arrest Immediately after Tourniquet Release during Epidural Anesthesia: A case report
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Jeon CY, Lee C, Kim TY, Song YK
- KMID: 2032608
- Korean J Anesthesiol.
- 2004 Dec;47(6):887-889.
- doi: 10.4097/kjae.2004.47.6.887
Sudden cardiac arrest during epidural anesthesia is a rare but catastrophic complication. It was recently reported that occurs in one per 10,000 epidural anesthesia cases. We report one case of... -
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- A Case of Malignant Hyperthermia during General Anesthesia with Sevoflurane: A case report
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Cheong YK, Jeon CY, Lee C, Song YK, Kim TY, Choi DH
- KMID: 2299121
- Korean J Anesthesiol.
- 2004 Sep;47(3):449-453.
- doi: 10.4097/kjae.2004.47.3.449
We experienced a malignant hyperthermia in 24-year-old male with sevoflurane during the mandibular prognathism surgery. The malignant hyperthermia emerged 150 minutes after induction of general anesthesia using propofol, rocuronium, sevoflurane,... -
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