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Transfusion support in hematopoietic stem cell transplantation

Jekarl DW, Kim JK, Han JH, Lee H, Yoo J, Lim J, Kim Y

Transfusion support for hematopoietic stem cell transplantation (HSCT) is an essential part of supportive care, and compatible blood should be transfused into recipients. As leukocyte antigen (HLA) matching is considered...
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Identification of Compound Heterozygous Mutations in the BBS7 Gene in a Korean Family with Bardet-Biedl Syndrome

Shin SJ, Kim M, Chae H, Kwon A, Kim Y, Kim SJ, Yoon HE, Jekarl DW, Lee S

No abstract available.
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Simultaneous Extracorporeal Membrane Oxygenation, Renal Replacement Therapy, and Plasma Exchange for Thrombocytopenia-Associated Multiple Organ Failure

Lee H, Yoo J, Lee J, Jekarl DW, Kim M, Kim Y

Thrombocytopenia-associated multiple organ failure (TAMOF) is a distinct type of sepsis related to thrombocytopenia, microangiopathic hemolysis, and multiple organ failure. TAMOF belongs to a spectrum of syndromes related to disseminated...
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Acute Hemolysis and Renal Failure caused by Hepatitis A Infection with Underlying Glucose-6-Phosphate Dehydrogenase Deficiency

Jekarl DW, Oh EJ, Park YJ, Han KJ, Lee SW, Park CW

Although glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder worldwide, it has rarely been reported among Korean. The patient was previously healthy 39 yr old male who showed...
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Three Cases of Anti-LW Antibody Identification at a Tertiary Hospital in Korea

Chae S, Kim KB, Yu H, Choi HJ, Jekarl DW, Lim J, Kim Y

The Landsteiner–Wiener (LW) antigen is a type of red blood cell antigen. Anti-LW appears in various situations, including alloantibodies, autoantibodies, and even transiently occurring antibodies. Anti-LW has similar characteristics to...
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Survey of Fungal Cultures and the Identification Tests Used by Diagnostic Laboratories in Korea

Lee S, Yu GG, Park KH, Lee SY, Jekarl DW, Yoon NS, Kim MN

BACKGROUND: The aim of this study was to investigate the current status of fungal cultures and the identification tests used by diagnostic laboratories in Korea. METHODS: From 22 October to 30...
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Thrombocytopenia Experienced by Healthy Peripheral Blood Stem Cell Donors at a Tertiary Hospital in Korea

Lee SJ, Chae S, Hwang JS, Yoo SH, Han J, Lee H, Jekarl DW, Kim Y

In healthy peripheral blood stem cell (PBSC) donors, rare cases of transient thrombocytopenia have been reported due to the administration of granulocyte colony-stimulating factor (G-CSF) or the apheresis itself. Meanwhile,...
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Clinical Presentation with High Penetrance in a Korean Family with Pulmonary Arterial Hypertension Associated with a BMPR2 Intron 3 Splice Site Pathogenic Variant

Kim MJ, Lee S, Jekarl DW, Chae H, Kim M, Jung HO, Jeon DS

Pathogenic variants of bone morphogenic protein receptor type 2 gene (BMPR2) are related to the majority of cases of heritable pulmonary arterial hypertension (PAH). Over 400 pathogenic variants have been...
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A Case of Autoimmune Hemolytic Anemia Caused by Anti-D and Anti-C in RhD Positive Patient

Jekarl DW, Lee GW, Kim Y, Kim M, Lim J, Han K, Cho SG, Lee JW

  • KMID: 1909662
  • Korean J Blood Transfus.
  • 2007 Dec;18(3):249-253.
We report a case of autoimmune hemolytic anemia caused by anti-D and anti-C in an RhD positive patient with Epstein-Barr Virus (EBV) infection. The patient achieved complete response by transfusion,...
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Correlation Between Fecal Toxin Enzyme Immunoassays and Disease Severity in Patients with Clostridioides difficile Infection in a Korean University Hospital

Han E, Lee S, Jekarl DW, Ji JS

Background: The aim of this study was to evaluate the clinical usefulness of the Clostridioides difficile toxin enzyme immunoassay (EIA) and nucleic acid amplification test (NAAT) in determining the...
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Analytical and Clinical Assessment of Prostate Specific Antigen Using an HISCL-5000 Chemiluminescence Immunoassay

Han J, Jekarl DW, Lee S, Kim M, Kim Y

Background: Prostate cancer (PCa) is the leading cause of cancer-related death worldwide. Prostate specific antigen (PSA) is a useful biomarker that can be screened for the diagnosis and prognosis of...
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Evaluating Diagnostic Tests for Helicobacter pylori Infection Without a Reference Standard: Use of Latent Class Analysis

Jekarl DW, Choi H, Kim JY, Lee S, Gweon TG, Lee HK, Kim Y

Evaluation of diagnostic tests requires reference standards, which are often unavailable. Latent class analysis (LCA) can be used to evaluate diagnostic tests without reference standards, using a combination of observed...
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Performance Evaluation of a Point of Care SelexOnTM B-Type Natriuretic Peptide Immunoassay

Jekarl DW, Lee S, Choi H, Cho SW, Park Hi

Background: This study was conducted to evaluate the analytical performance of the SelexOnTM B-type natriuretic peptide (BNP) assay (Osang Healthcare Inc., Korea), a new rapid lateral flow immunoassay for point...
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Usefulness of Reference Change Values for Delta Check Limits in Clinical Laboratory Testing

Lee S, Son JO, Kwon H, Park KH, Yu GG, Han E, Jekarl DW, Kim Y

Background: In this study, the usefulness of within-subject biological coefficient of variation (CVI) and reference change values (RCVs) for delta check limits were investigated by comparing the population distributionbased delta...
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Evaluation of the Automated Immunohematology Analyzer DAYMATE M

Yoo J, Yu H, Choi H, Lee GW, Song YS, Lee S, Jekarl DW, Kim Y

BACKGROUND: An automated immunohematology analyzer, DAYMATE M (DAY Medical, Switzerland), has been recently developed. The potential of this analyzer to improve test results has been evaluated. METHODS: A total of 300...
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Experience of a Performing Alternative Assessment Procedure for Tests without External Proficiency Test Program

Jekarl DW, Lee GW, Kim Y, Song YS, Jang HS, Park GH, Youn SO, Jo SJ, Park GH, Lim S, Lee MS

  • KMID: 1442278
  • Korean J Blood Transfus.
  • 2011 Dec;22(3):198-203.
BACKGROUND: Proficiency testing is part of a total quality management program that provides objective evidence of clinical laboratory testing competence for customers, accrediting bodies, and regulatory agencies. Performing alternative assessment...
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JAK2 V617F mutation in myelodysplastic syndrome, myelodysplastic syndrome/myeloproliferative neoplasm, unclassifiable, refractory anemia with ring sideroblasts with thrombocytosis, and acute myeloid leukemia

Jekarl DW, Han SB, Kim M, Lim J, Oh EJ, Kim Y, Kim HJ, Min WS, Han K

BACKGROUND: The JAK2 V617F mutation has been noted in the cases of polycythemia vera, essential thrombocythemia, and primary myelofibrosis patients. This mutation occurs less frequently in acute myeloid leukemia (AML)...
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Clinical Significance of Fecal Lactoferrin and Multiplex Polymerase Chain Reaction in Patients with Acute Diarrhea

Lee HM, Lee S, Lee BI, Jekarl DW, Song JY, Choi HJ, Kang BK, Im EJ, Kim JS, Kim JI, Kim BW, Choi H

BACKGROUND/AIMS: The diagnostic yield of fecal leukocyte and stool cultures is unsatisfactory in patients with acute diarrhea. This study was performed to evaluate the clinical significance of the fecal lactoferrin...
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Clinical Significance of Inflammatory Biomarkers in Acute Pediatric Diarrhea

Park Y, Son M, Jekarl DW, Choi HY, Kim SY, Lee S

PURPOSE: The aim of this study was to evaluate the clinical significance of inflammatory biomarkers in acute infectious diarrhea among children. METHODS: Clinical parameters including fever, bacterial and viral etiology based...
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Impact of Genetic Abnormalities on the Prognoses and Clinical Parameters of Patients with Multiple Myeloma

Jekarl DW, Min CK, Kwon A, Kim H, Chae H, Kim M, Lim J, Kim Y, Han K

BACKGROUND: We reviewed patients with multiple myeloma (MM) in order to assess the incidence of genetic abnormalities and their associations with clinical parameters, risk groups, and prognosis. METHODS: A total of...
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