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Increased Expression of S100B and RAGE in a Mouse Model of Bile Duct Ligation-induced Liver Fibrosis

Park JW, Kim MJ, Kim SE, Kim HJ, Jeon YC, Shin HY, Park SJ, Jang MK, Kim DJ, Park CK, Choi EK

Background: Liver fibrosis is defined as the accumulation of the extracellular matrix and scar formation. The receptor for advanced glycation end products (RAGE) has been demonstrated to participate in fibrogenesis....
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Predictors for the need for endoscopic therapy in patients with presumed acute upper gastrointestinal bleeding

Kim SS, Kim KU, Kim SJ, Seo SI, Kim HS, Jang MK, Kim HY, Shin WG

BACKGROUND/AIMS: Selecting patients with an urgent need for endoscopic hemostasis is difficult based only on simple parameters of presumed acute upper gastrointestinal bleeding. This study assessed easily applicable factors to...
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Risk of Peptic Ulcer Bleeding Associated with Helicobacter pylori Infection, Nonsteroidal Anti-inflammatory Drugs, and Low-dose Aspirin Therapy in Peptic Ulcer Disease: A Case-control Study

Seo SI, Kang JG, Kim HS, Shin WG, Jang MK, Lee JH, Kim HY

BACKGROUND/AIMS: The association between Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin therapy as a risk factor for peptic ulcer bleeding (PUB) remains unclear. This study investigated...
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Belief factors associated with breastfeeding intentions of single women: Based on the theory of planned behavior

Jang MK, Lee SM, Khil JM

PURPOSE: This study was conducted to examine the behavioral intentions of breastfeeding in single women using the theory of planned behavior. METHODS: The questionnaires were distributed to 350 single women in...
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A Case of Multiple Hypervascular Hyperplastic Liver Nodules in a Patient with No History of Alcohol Abuse or Chronic Liver Diseases

Do BJ, Park IY, Rhee SY, Song JK, Jang MK, Cho SJ, Nam ES, Yun EJ

Up-to-date imaging modalities such as three-dimensional dynamic contrast-enhanced CT (3D CT) and MRI may contribute to detection of hypervascular nodules in the liver. Nevertheless, distinguishing a malignancy such as hepatocellular...
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Entecavir Resistance at rtS202, rtM250 May Cause Poor Viral Response to Tenofovir-based Rescue Therapy in Chronic Hepatitis B

Kim SE, Park JW, Kim HS, Suk KT, Jang MK, Park SH, Lee MS, Kim DJ, Park CK

BACKGROUND/AIMS: Long-term use of nucleos(t)ide analogues (NA) may lead to genotypic and/or phenotypic resistance of the hepatitis B virus (HBV). We investigated the efficacy of tenofovir-based rescue therapy in chronic...
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Phylogenetic Analyses of HBV Pre-S/S Genes in Mother-Child Pairs with Long-Term Infection by Presumed Vertical Transmission

Kim HS, Choi BY, Choi HS, Shin WG, Kim KH, Lee JH, Kim HY, Jang MK, Kim DJ, Lee MS, Park CK

Vertical transmission from mother to child, the main route of chronic hepatitis B virus (HBV) infection in the East Asia, is considered one of the most important predictors for the...
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The Simple Predictors of Pseudomembranous Colitis in Patients with Hospital-Acquired Diarrhea: A Prospective Observational Study

Yang BK, Do BJ, Kim EJ, Lee JU, Kim MH, Kang JG, Kim HS, Kim KH, Jang MK, Lee JH, Kim HY, Shin WG

  • KMID: 1774527
  • Gut Liver.
  • 2014 Jan;8(1):41-48.
BACKGROUND/AIMS: As the incidence rate of and mortality from pseudomembranous colitis (PMC) are increasing worldwide, it is important to study the simple predictive risk factors for PMC among patients with...
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Investigation into the Use of Complementary and Alternative Medicine and Factors Affecting Use in Korean Patients with Brain Tumors

Shin YS, Lee JA, Bae SH, Lee SY, Jang MK

  • KMID: 2295631
  • J Korean Acad Fundam Nurs.
  • 2013 May;20(2):147-156.
PURPOSE: The study was done to define complementary and alternative medicine (CAM) use among primary brain tumor patients and factors influencing use. METHODS: The study was conducted with convenience sampling in...
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Sasa borealis extract exerts an antidiabetic effect via activation of the AMP-activated protein kinase

Nam JS, Chung HJ, Jang MK, Jung IA, Park SH, Cho SI, Jung MH

  • KMID: 2313644
  • Nutr Res Pract.
  • 2013 Feb;7(1):15-21.
Leaf of Sasa borealis, a species of bamboo, has been reported to exhibit anti-hyperglycemic effect. However, its antidiabetic mechanism is not fully understood. In this study, we examined whether an...
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A Case of Clostridium Liver Abscess with Sepsis

Lee SH, Kim HS, Kim SJ, Shin WG, Kim KH, Jang MK, Lee JH, Kim HY

Clostridial septicemia usually occurrs in patients with immunocompromised diseases such as diabetes and malignancy. Clostridial liver abscess is very rare but highly fatal. We experienced a case of Clostridial septicemia...
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The COX-2-1195AA Genotype Is Associated with Diffuse-Type Gastric Cancer in Korea

Shin WG, Kim HJ, Cho SJ, Kim HS, Kim KH, Jang MK, Lee JH, Kim HY

  • KMID: 2053493
  • Gut Liver.
  • 2012 Jul;6(3):321-327.
BACKGROUND/AIMS: The potential role of the cyclooxygenase (COX)-2 polymorphism has been reported in relation to the risk of gastrointestinal tract malignancies. Therefore, we investigated whether COX-2 polymorphisms are associated with...
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Monitoring of antibiotic resistance in bacteria isolated from laboratory animals

Goo JS, Jang MK, Shim SB, Jee SW, Lee SH, Bae CJ, Park S, Kim KJ, Kim JE, Hwang IS, Lee HR, Choi SI, Lee YJ, Lim CJ, Hwang DY

The drug resistance of microorganisms isolated from laboratory animals never treated with antibiotics is being reported consistently, while the number of laboratory animals used in medicine, pharmacy, veterinary medicine, agriculture,...
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Spontaneous Bacterial Peritonitis with Sepsis Caused by Enterococcus hirae

Sim JS, Kim HS, Oh KJ, Park MS, Jung EJ, Jung YJ, Kang DG, Seo SI, Kim WJ, Jang MK

Selective intestinal decontamination (SID) with norfloxacin has been widely used for the prophylaxis of spontaneous bacterial peritonitis (SBP) because of a high recurrence rate and preventive effect of SID for...
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The Simple Predictive Factors of Emergency Endoscopy for Non-variceal Acute Upper Gastrointestinal Bleeding

Lee SM, Lee SH, Kim SJ, Park HW, Kim HS, Kim KH, Jang MK, Lee JH, Kim HY, Shin WG

BACKGROUND/AIMS: Although endoscopy is an important diagnostic method for acute upper gastrointestinal bleeding (AUGIB), the guideline of emergency endoscopy for AUGIB is not yet established. This study was performed to...
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A case of pedunculated hepatic hemangioma mimicking submucosal tumor of the stomach

Moon HK, Kim HS, Heo GM, Shin WG, Kim KH, Jang MK, Lee JH, Kim HY, Kim DJ, Cho SJ

Hepatic hemangioma is the most common benign tumor of the liver. Most such hemangiomas are small, asymptomatic, and have an excellent prognosis. Giant hepatic hemangioma has been reported in the...
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The Comparison between 6th and 7th International Union Against Cancer/American Joint Committee on Cancer Classification for Survival Prognosis of Gastric Cancer

Kim SS, Choi BY, Seo SI, Jung MY, Choi HS, Ahn SM, Choi WH, Kim HS, Kim KH, Jang MK, Lee JH, Kim HY, Shin WG

BACKGROUND/AIMS: The tumor-node-metastasis (TNM) staging is an useful system to assess the prognosis of any solid cancer. As new TNM staging classification of 7th stomach cancer was revised in 2009,...
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Right Ventricular Remodeling Determines Tricuspid Valve Geometry and the Severity of Functional Tricuspid Regurgitation: A Real-Time 3-Dimensional Echocardiography Study

Song JM, Jang MK, Kim YJ, Kim DH, Kang DH, Song JK

BACKGROUND AND OBJECTIVES: Right ventricle (RV) remodeling can determine tricuspid valve (TV) geometry and the severity of functional tricuspid regurgitation (TR). SUBJECTS AND METHODS: In 53 patients with various degrees of...
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Comparison of methods for proanthocyanidin extraction from pine (Pinus densiflora) needles and biological activities of the extracts

Kim NY, Jang MK, Lee DG, Yu KH, Jang H, Kim M, Kim SG, Yoo BH, Lee SH

  • KMID: 2421535
  • Nutr Res Pract.
  • 2010 Feb;4(1):16-22.
Flavonoids are known to be effective scavengers of free radicals. In particular, proanthocyanidins are flavonoids that possess cardiovascular protection, antioxidative activities, and immunomodulatory activities. Here, we evaluated proanthocyanidin contents in...
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Patient Safety Program and Safety Culture

Kim YM, Kim SY, Kim MY, Kim JH, Lee SK, Jang MK

  • KMID: 2320934
  • J Korean Acad Nurs Adm.
  • 2010 Dec;16(4):455-465.
PURPOSE: To determine the impact of the Patient Safety Program on the safety culture of nursing department. METHODS: Patient Safety Program focused on medication safety was launched by QI team and...
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