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Effect of Remote Ischemic Preconditioning on Maximal Exercise Tolerance in Young Adults

Yoon ES, Jae SY

PURPOSE: Remote ischemic preconditioning (RIPC), induced by repeated bouts of ischemia followed by reperfusion of the arm or leg is a noninvasive strategy to protect a target organ against oxidative...
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Endogenous Agmatine Induced by Ischemic Preconditioning Regulates Ischemic Tolerance Following Cerebral Ischemia

Kim JH, Kim JY, Jung JY, Lee YW, Lee WT, Huh SK, Lee JE

Ischemic preconditioning (IP) is one of the most important endogenous mechanisms that protect the cells against ischemia-reperfusion (I/R) injury. However, the exact molecular mechanisms remain unclear. In this study, we...
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The optimal duration of ischemic preconditioning for renal ischemia-reperfusion injury in mice

Choi HS, Hwang JK, Kim JG, Hwang HS, Lee SJ, Chang YK, Kim JI, Moon IS

PURPOSE: The aim of the present study was to investigate the protective effects of ischemic preconditioning for different periods of time and to elucidate the optimal safe ischemic preconditioning time...
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Neurogenic pathways in remote ischemic preconditioning induced cardioprotection: Evidences and possible mechanisms

Aulakh AS, Randhawa P, Singh N, Jaggi AS

Remote ischemic preconditioning (RIPC) is an intrinsic phenomenon whereby 3~4 consecutive ischemia-reperfusion cycles to a remote tissue (noncardiac) increases the tolerance of the myocardium to sustained ischemiareperfusion induced injury. Remote...
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Remote Ischemic Preconditioning Enhances the Expression of Genes Encoding Antioxidant Enzymes and Endoplasmic Reticulum Stress-Related Proteins in Rat Skeletal Muscle

Park UJ, Kim HT, Cho WH, Park JH, Jung HR, Kim MY

PURPOSE: Ischemic preconditioning (IPC), including remote IPC (rIPC) and direct IPC (dIPC), is a promising method to decrease ischemia-reperfusion (IR) injury. This study tested the effect of both rIPC and...
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The Effect of Ischemic Preconditioning on the Expression of Serum Cytokines after 2 Hours Ischemia and Timely Reperfusion in the Hindlimb of Mice

Jin JH, Kim SJ, Seo Y, Kim S

The large volume of reactive oxygen species are generated during reperfusion after transient or post-procedural ischemia, which leads to cell injury. This ischemia-reperfusion (IR) injury may cause local and even...
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Effect of remote ischemic preconditioning on cognitive function after off-pump coronary artery bypass graft: a pilot study

Joung KW, Rhim JH, Chin JH, Kim WJ, Choi DK, Lee EH, Hahm KD, Sim JY, Choi IC

BACKGROUND: Several studies have shown in animal models that remote ischemic preconditioning (rIPC) has a neuroprotective effect. However, a randomized controlled trial in human subjects to investigate the neuroprotective effect...
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Effects of Ischemic Preconditioning of Different Intraoperative Ischemic Times of Vascularized Bone Graft Rabbit Models

Halim AS, Wan Ahmad Kamal WSR, Noor NM, Abdullah S

BACKGROUND: Ischemic preconditioning has been shown to improve the outcomes of hypoxic tolerance of the heart, brain, lung, liver, jejunum, skin, and muscle tissues. However, to date, no report of...
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Effects of Repetitive Ischemic Preconditioning on the Expression of Nitric Oxide Synthase in Tibialis Anterior and Soleus Muscles of the Rat

Koh BC, Seo YK, Shin CO, Chun SK, Paik DJ

  • KMID: 2283412
  • Korean J Phys Anthropol.
  • 2007 Sep;20(3):213-224.
Nitric oxide synthases (NOSs) that catalyzed the conversion of L-arginine to nitric oxide and L-citrulline play a role in ischemic-reperfusion injury. The purpose of this study was to observe the...
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Renal Protective Effects of Opposite Renal Ischemic Preconditioning against Renal Ischemic Reperfusion Injury in Mice

Joo JD, Kim DW, Kang YJ, Kim YS, Jeon YS, In JH, Choi JW, Park YJ

BACKGROUND: Acute renal failure (ARF) results from renal ischemic reperfusion (IR) injury and is a major contributor to the morbidity and mortality encountered during the perioperative period. It was previously...
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Regional Differences in Mitochondrial Anti-oxidant State during Ischemic Preconditioning in Rat Heart

Thu VT, Cuong DV, Kim N, Youm JB, Warda M, Park WS, Ko JH, Kim E, Han J

  • KMID: 1512908
  • Korean J Physiol Pharmacol.
  • 2007 Apr;11(2):57-64.
Ischemic preconditioning (IPC) is known to protect the heart against ischemia/reperfusion (IR)-induced injuries, and regional differences in the mitochondrial antioxidant state during IR or IPC may promote the death or...
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Effects of Repetitive Ischemic Preconditioning on the Phosphorylation of Akt and Expression of HSP72 and HSP90 in the Rat Tibialis Anterior and Soleus Muscles

Seo YK, Seo DY, Jeon SK, Park HJ, Paik DJ

  • KMID: 2283227
  • Korean J Phys Anthropol.
  • 2006 Dec;19(4):287-299.
Akt, heat shock protein (HSP72)72, and HSP90 induced by ischemic preconditioning protect cells from the ischemic injury. The purpose of this study was to examine the alterations of the level...
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Effects of Ischemic Preconditioning and Propofol on Cardiac Function and Coronary Flow following Cold Cardioplegia and Reperfusion in Isolated Rat Heart

Park SJ, Choi SU, Choi WH, Kong MH, Lee MK, Kim NS

BACKGROUND: The interaction between ischemic preconditioning (IPC) and propofol-induced cardioprotective effects during prolonged cold ischemia has not been studied yet. The purpose of this study is to investigate the effects...
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Inhibiting Effect of Amiodarone to Protective Action against Ischemia/Reperfusion Injury Induced by Ischemic Preconditioning

Koo EH, Park CG, Lim SH, Park YC

odarone. Isovolumetric left ventricular end systolic pressure (LVESP), left ventricular end diastolic pressure (LVEDP), dP/dtMAX and heart rate were measured. RESULTS: Group II showed more recovered LVESP, less developed ventricular...
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Effects of Repetitive Ischemic Preconditioning on the Expression of Cu,ZnSOD and MnSOD in Rectus Femoris Muscles of Rats

Jeon SK, Seo YK, Chang NJ, Park HZ, Lee SW, Paik DJ

  • KMID: 1583638
  • Korean J Phys Anthropol.
  • 2006 Sep;19(3):179-189.
The present study was performed to investigate the dynamics of Cu,ZnSOD and MnSOD expression following courses of reperfusion after repetitive ischemic preconditioning on the left rectus femoris muscle of Spraque-Dawley rats. Nine or...
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The Effects of Ischemic Preconditioning and K(ATP) channel Activation on the Expression of the PKC-epsilon, NF-kappaB and AP-1 in Ischemia-reperfused Rat Heart

Ahn DC, Chun SH, Seo YK, Jeon SK, Park HJ, Lee SW, Sim JH, Paik DJ

  • KMID: 1583637
  • Korean J Phys Anthropol.
  • 2006 Sep;19(3):165-178.
This study was aimed to elucidate the effects of K(ATP) activation during IPC on the PKC-epsilon, NF-kappaB and AP-1 in ischemia-reperfused rat hearts. SD male rats weighting from 300 to 350...
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Do Ischemic Preconditioning and Propofol Have Synergistic Effect on Reducing Adhesion of Polymorphonuclear Neutrophils?

Kim JY, Lim CH, Lim HJ

BACKGROUND: Ischemic preconditioning (IPC) and propofol has been demonstrated to inhibit postischemic adhesion of PMNs on coronary vascular endothelium, respectively. The purpose of this study is to investigate whether IPC...
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Alteration of PKC, PKC theta, NF-kappa B and AP-1 in Ischemic-reperfused Soleus Muscle of Rat with Ischemic Preconditioning

Kim TS, Kim JH, Kim KW

  • KMID: 1848289
  • J Korean Orthop Res Soc.
  • 2004 Oct;7(2):184-190.
PURPOSE: This study was designed to examine the expression patterns of PKC, PKC theta which is a house-keeping member of PKC family in the skeletal muscle, and two redox sensitive...
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Effects of Sevoflurane and Ischemic Preconditioning on Neurologic Injury and Bcl-2 Family Protein mRNA Expression after Transient Spinal Ischemia in the Rats

Kang SH, Kim ES, Baek SH, Kwon JY

  • KMID: 2228546
  • Korean J Crit Care Med.
  • 2004 Jun;19(1):20-31.
BACKGROUND: Spinal cord injury occurring as the result of surgical repair of thoracic and thoracoabdominal aortic disease remains a devastating complication. Anesthetic and ischemic preconditioning have been known to prevent...
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The Effect of Preinfarction Angina as Ischemic Preconditioning on Myocardial Protection

Choi TY, Tahk SJ, Yoon MH, Choi SY, Kim MC, Yang HM, Choi JH, Zheng ZG, Qi L, Chang HJ, Hwang GS, Shin JH

BACKGROUND AND OBJECTIVES: By measuring the coronary flow reserve (CFR) and echocardiographic left ventricular function, the purpose of this study was to evaluate the effect of pre-infarction angina (PA) on...
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