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A Clinical Study on the Association between Sensitive Skin and Acne in Patients with Acne

Choi W, Myung KB, Hahn HJ, Cheong SH

  • KMID: 2457685
  • Korean J Dermatol.
  • 2019 Aug;57(7):355-362.
BACKGROUND: Acne is a common inflammatory skin disease that involves the seborrheic area, developing not only in adolescence but also in adulthood. Abnormal epidermal barrier function in acne is reported...
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Extravasation Wound Care in the Neonatal Intensive Care Unit

Cho KS, Ahn HC, Lee JH, Lim SY, Lee HJ, Park HK

BACKGROUND: Extravasation injuries occurring in neonates can have severe consequences. Because many clinicians are not familiar with the vesicant-like effect of several commonly used medications, early extravasation wound management can...
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A Clinical Study Including Patch Test of Rosacea Patients

Lee KG, Hahn HJ, Myung KB, Cheong SH

  • KMID: 2446917
  • Korean J Dermatol.
  • 2019 Mar;57(3):117-125.
BACKGROUND: Rosacea is a relatively common inflammatory skin disease characterized by central facial erythema that persists for several months or longer. Experimental studies have demonstrated that rosacea compromises the epidermal...
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Anti-Helicobacter pylori, Anti-apoptotic, and Cytoprotective Effects of Threonine Synthesized from Corynebacterium glutamicum in Gastric Epithelial Cells

An JM, Kim YS, Hong YG, Hah BS, Sohn MS, Hahm KB

BACKGROUND/AIMS: Among irritants causing gastric ulcer, Helicobacter pylori (H. pylori) might be pivotal, after which eradication became essential way in either inhibiting ulcerogenesis or preventing ulcer recurrence. Since threonine is...
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Factors Related to Extravasation of Non-chemotherapy Vesicant Drugs in Peripheral Vein Catheters

Lee JM, Lee J, Jang YS, Kim YH

PURPOSE: This study aimed to investigate the incidence of intravenous extravasation and the risk factors associated with the use of peripheral intravenous catheters in adults. METHOD: This prospective observational study included...
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Response to Nonallergenic Irritants in Children With Allergic and Nonallergic Rhinitis

Baek JH, Cho E, Kim MA, Lee SW, Kang YS, Sheen YH, Jee HM, Jung YH, Han MY

PURPOSE: Nonallergenic irritants can aggravate the symptoms of rhinitis. We investigated the clinical responses of children with allergic rhinitis (AR) and nonallergic rhinitis (NAR) to nonallergenic irritants, and identified factors...
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Long-Term Effects of Bone Marrow-Derived Mesenchymal Stem Cells in Dextran Sulfate Sodium-Induced Murine Chronic Colitis

Lee HJ, Oh SH, Jang HW, Kwon JH, Lee KJ, Kim CH, Park SJ, Hong SP, Cheon JH, Kim TI, Kim WH

BACKGROUND/AIMS: Bone marrow-derived mesenchymal stem cells (BM-MSCs) have shown beneficial effects in experimental colitis models, but the underlying mechanisms are not fully understood. We investigated the long-term effects of BM-MSCs,...
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Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats

Choi YJ, Kim N, Lee JY, Nam RH, Seo JH, Lee S, Kim HJ, Choi YJ, Lee HS, Lee DH

BACKGROUND/AIMS: This study aimed to examine the gastroprotective effects of PMK-S005, which is a synthetic S-allyl-L-cysteine (SAC; a sulfur-containing amino acid), against acute ethanol-induced gastric damage in rats. METHODS: Sprague-Dawley rats...
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Smoking and Hand Dermatitis in the United States Adult Population

Lai YC, Yew YW

BACKGROUND: Hand dermatitis is a common chronic relapsing skin disease resulting from a variety of causes, including endogenous predisposition and environmental exposures to irritants and allergens. Lifestyle factors such as...
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Quantitative determination of 12-hydroxyeicosatetraenoic acids by chiral liquid chromatography tandem mass spectrometry in a murine atopic dermatitis model

Hong SH, Han JE, Ko JS, Do SH, Lee EH, Cho MH

Atopic dermatitis, one of the most important skin diseases, is characterized by both skin barrier impairment and immunological abnormalities. Although several studies have demonstrated the significant relationship between atopic dermatitis...
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Type and treatment of toxic mushroom poisoning in Korea

Sohn CH

To eat unidentified or misidentified mushrooms taken from the wild can be very dangerous. In the vast majority of toxic mushroom ingestions in Korea, the mushroom was incorrectly identified. In...
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Patch Testing with Dental Screening Series in Oral Disease

Kim TW, Kim WI, Mun JH, Song M, Kim HS, Kim BS, Kim MB, Ko HC

BACKGROUND: The oral mucosa is constantly exposed to several irritants and allergens including dental materials, but the role of contact allergy in oral disease is obscure. OBJECTIVE: To analyze positive patch...
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Evaluation of Eye Irritation Potential of Solid Substance with New 3D Reconstructed Human Cornea Model, MCTT HCE(TM)

Jang WH, Jung KM, Yang HR, Lee M, Jung HS, Lee SH, Park M, Lim KM

The eye irritation potential of drug candidates or pharmaceutical ingredients should be evaluated if there is a possibility of ocular exposure. Traditionally, the ocular irritation has been evaluated by the...
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Induction of a Hardening Phenomenon and Quantitative Changes of Ceramides in Stratum Corneum

Park SY, Kim JH, Cho SI, Kim KI, Cho HJ, Park CW, Lee CH, Kim HO

BACKGROUND: Hardening phenomenon of human skin after repeated exposure to the irritants is well-known, but the precise mechanism remains elusive. OBJECTIVE: To modify the previous experimental model of hardening phenomenon by...
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Wet-work Exposure: A Main Risk Factor for Occupational Hand Dermatitis

Behroozy A, Keegel TG

Wet-work can be defined as activities where workers have to immerse their hands in liquids for >2 hours per shift, or wear waterproof (occlusive) gloves for a corresponding amount of...
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The pH of water from various sources: an overview for recommendation for patients with atopic dermatitis

Kulthanan , Nuchkull P, Varothai S

BACKGROUND: Patients with atopic dermatitis (AD) have increased susceptibility to irritants. Some patients have questions about types of water for bathing or skin cleansing. OBJECTIVE: We studied the pH of water...
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Overview of atopic dermatitis

Kim KH

Atopic dermatitis (AD) is a very common chronic disease that reportedly affects 10%-20% of the general population. The prevalence of AD appears to be steadily increasing, at least in developing...
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Expression of Bitter Taste Receptors in Human Nasal Respiratory Epithelium

An JM, Wu HW, Kim HJ, Kim CH, Moon SJ

  • KMID: 2170774
  • Int J Oral Biol.
  • 2012 Jun;37(2):57-62.
The nasal cavity encounters various irritants during inhalation such as dust and pathogens. To detect and remove these irritants, it has been postulated that the nasal mucosa epithelium has a...
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Pruritus Ani

Song SG, Kim SH

Pruritus ani is an unpleasant cutaneous sensation that induces the desire to scratch the skin around the anal orifice. It may start insidiously and appears in 1% to 5% of...
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The Roles of Reactive Oxygen Species Produced by Contact Allergens and Irritants in Monocyte-derived Dendritic Cells

Byamba D, Kim TG, Kim DH, Je JH, Lee MG

BACKGROUND: Although reactive oxygen species (ROS) have been produced in both mouse bone marrow-derived dendritic cells (DCs) and XS-106 DCs by contact sensitizers and irritants in previous studies, the generation...
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