- Hormonal Regulation of Hematopoietic Stem Cells and Their Niche: A Focus on Estrogen
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Heo HR, Chen L, An B, Kim KS, Ji J, Hong SH
- KMID: 2380795
- Int J Stem Cells.
- 2015 May;8(1):18-23.
- doi: 10.15283/ijsc.2015.8.1.18
Self-renewal and differentiation are hallmarks of stem cells and controlled by various intrinsic and extrinsic factors. Increasing evidence indicates that estrogen (E2), the primary female sex hormone, is involved in... -
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- The Contribution of Resident Vascular Stem Cells to Arterial Pathology
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Orlandi A
- KMID: 2380794
- Int J Stem Cells.
- 2015 May;8(1):9-17.
- doi: 10.15283/ijsc.2015.8.1.9
Intimal accumulation of smooth muscle cells contributes to the development and progression of atherosclerotic lesions and restenosis following endovascular procedures. Arterial smooth muscle cells display heterogeneous phenotypes in both physiological... -
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- Stem Cell Research in Pakistan; Past, Present and Future
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Zahra SA, Muzavir SR, Ashraf S, Ahmad A
- KMID: 2380793
- Int J Stem Cells.
- 2015 May;8(1):1-8.
- doi: 10.15283/ijsc.2015.8.1.1
BACKGROUND AND OBJECTIVES: Stem cells have proved to have great therapeutic potential as stem cell treatment is replacing traditional ways of treatment in different disorders like cancer, aplastic anemia, stroke,... -
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- Combination Cell Therapy with Mesenchymal Stem Cells and Neural Stem Cells for Brain Stroke in Rats
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Hosseini S, Farahmandnia M, Razi Z, Delavari S, Shakibajahromi B, Sarvestani FS, Kazemi S, Semsar M
- KMID: 2380803
- Int J Stem Cells.
- 2015 May;8(1):99-105.
- doi: 10.15283/ijsc.2015.8.1.99
OBJECTIVES: Brain stroke is the second most important events that lead to disability and morbidity these days. Although, stroke is important, there is no treatment for curing this problem. Nowadays,... -
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- Regulation of Stem Cell Fate by ROS-mediated Alteration of Metabolism
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Ryu JM, Lee HJ, Jung YH, Lee KH, Kim DI, Kim JY, Ko SH, Choi GE, Chai II, Song EJ, Oh JY, Lee SJ, Han HJ
- KMID: 2380796
- Int J Stem Cells.
- 2015 May;8(1):24-35.
- doi: 10.15283/ijsc.2015.8.1.24
Stem cells have attracted much attention due to their distinct features that support infinite self-renewal and differentiation into the cellular derivatives of three lineages. Recent studies have suggested that many... -
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- Cell Sources, Liver Support Systems and Liver Tissue Engineering: Alternatives to Liver Transplantation
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Lee SY, Kim HJ, Choi D
- KMID: 2380797
- Int J Stem Cells.
- 2015 May;8(1):36-47.
- doi: 10.15283/ijsc.2015.8.1.36
The liver is the largest organ in the body; it has a complex architecture, wide range of functions and unique regenerative capacity. The growing incidence of liver diseases worldwide requires... -
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- New Strategies for Overcoming Limitations of Mesenchymal Stem Cell-Based Immune Modulation
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Kim N, Cho SG
- KMID: 2380799
- Int J Stem Cells.
- 2015 May;8(1):54-68.
- doi: 10.15283/ijsc.2015.8.1.54
Mesenchymal stem cells (MSCs) have rapidly been applied in a broad field of immune-mediated disorders since the first successful clinical use of MSCs for treatment of graft-versus-host disease. Despite the... -
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- Attachment and Differentiation of Human Umbilical Cord Stem Cells on to the Tooth Root Surface with and without the Use of Fibroblast Growth Factor-An In Vitro Study
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George JP, Chakravarty P, Chowdhary , Purushothama H, Rao JA
- KMID: 2380802
- Int J Stem Cells.
- 2015 May;8(1):90-98.
- doi: 10.15283/ijsc.2015.8.1.90
BACKGROUND AND OBJECTIVES: The purpose of this first of its kind study was to analyse the growth, development and attachment of cultured human umbilical cord stem cells alone or supplemented... -
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- Direct Differentiation of Adult Ocular Progenitors into Striatal Dopaminergic Neurons
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Ahmad I, Zhao X, Parameswaran S, Destache C, Rodriguez-Sierra J, Thoreson W, Ahmad H, Sorrentino J, Balasubramanian S
- KMID: 2380804
- Int J Stem Cells.
- 2015 May;8(1):106-114.
- doi: 10.15283/ijsc.2015.8.1.106
Parkinson's disease, characterized by motor dysfunction due to the loss of nigrostriatal dopaminergic neurons, is one of the most prevalent age-related neurodegenerative disorders. Given there is no current cure, the... -
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- Bone Marrow Mesenchymal Stem Cell Transplantation in a Rabbit Corneal Alkali Burn Model (A Histological and Immune Histo-chemical Study)
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Ahmed SK, Soliman AA, Omar SM, Mohammed W
- KMID: 2380800
- Int J Stem Cells.
- 2015 May;8(1):69-78.
- doi: 10.15283/ijsc.2015.8.1.69
BACKGROUND: Alkali-burned corneas can seldom heal properly to restore corneal transparency. Treatment of this severe disorder of the ocular surface remains a challenge. AIM OF THE WORK: was to investigate whether... -
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- Epigenetic Alterations of IL-6/STAT3 Signaling by Placental Stem Cells Promote Hepatic Regeneration in a Rat Model with CCl4-induced Liver Injury
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Jung J, Moon JW, Choi JH, Lee YW, Park SH, Kim GJ
- KMID: 2380801
- Int J Stem Cells.
- 2015 May;8(1):79-89.
- doi: 10.15283/ijsc.2015.8.1.79
BACKGROUND: Human chorionic plate-derived mesenchymal stem cells (CP-MSCs) isolated from the placenta have been reported to demonstrate therapeutic effects in animal models of liver injury; however, the underlying epigenetic mechanism... -
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- Cell Therapy and Tissue Engineering Approaches for Cartilage Repair and/or Regeneration
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Mardones R, Jofre CM, Minguell J
- KMID: 2380798
- Int J Stem Cells.
- 2015 May;8(1):48-53.
- doi: 10.15283/ijsc.2015.8.1.48
Articular cartilage injuries caused by traumatic, mechanical and/or by progressive degeneration result in pain, swelling, subsequent loss of joint function and finally osteoarthritis. Due to the peculiar structure of the... -
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