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Expression of Bitter Taste Receptors in Human Nasal Respiratory Epithelium

An JM, Wu HW, Kim HJ, Kim CH, Moon SJ

  • KMID: 2170774
  • Int J Oral Biol.
  • 2012 Jun;37(2):57-62.
The nasal cavity encounters various irritants during inhalation such as dust and pathogens. To detect and remove these irritants, it has been postulated that the nasal mucosa epithelium has a...
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Inhibitory Effect of SPA0355, a Thiourea Analogue, on Inflammation and Alveolar Bone Loss in Rats with Ligature-Induced Periodontitis

Bak EJ, Kim JH, Lee DE, Park BH, Ryu JH, Cha JH, Jeon R, Yoo YJ

  • KMID: 2170775
  • Int J Oral Biol.
  • 2012 Jun;37(2):63-68.
It has been documented that SPA0355 exerts anti-inflammatory effects via the inhibition of nuclear factor-kappaB activation. In present study, we investigated the inhibitory effects of SPA0355 on periodontitis in an...
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Differential Expression of Osteonectin in the Rat Developing Molars

Kim JH, Yoo HI, Oh MH, Yang SY, Kim MS, Kim SH

  • KMID: 2170773
  • Int J Oral Biol.
  • 2012 Jun;37(2):51-56.
Tooth development involves bud, cap, bell and hard tissue formation stages, each of which is tightly controlled by regulatory molecules. The aim of this study was to identify genes that...
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Effect of Mineral Trioxide Aggregate and Calcium Hydroxide on Reparative Dentin Formation in Rats

Ra JY, Lee W, Kim HJ

  • KMID: 2170777
  • Int J Oral Biol.
  • 2012 Jun;37(2):77-83.
We investigated the pulpal response to direct pulp capping in rat molar teeth using mineral trioxide aggregate (MTA) and calcium hydroxide (CH). A palatal cavity was prepared in rat maxillary...
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A Hyperactive Neutrophil Phenotype in Aggressive Periodontitis

Kim KY, Kim MK, Choi YS, Kim YC, Jo AR, Rhyu IC, Choi Y

  • KMID: 2170776
  • Int J Oral Biol.
  • 2012 Jun;37(2):69-75.
Although neutrophils function in both defense and tissue destruction, their defensive roles have rarely been studied in association with periodontitis. We hypothesized that peripheral neutrophils are pre-activated in vivo in...
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Establishment of High Throughput Screening System Using Human Umbilical Cord-derived Mesenchymal Stem Cells

Park EG, Cho T, Oh K, Kwon SK, Lee DS, Park SB, Cho J

  • KMID: 2170772
  • Int J Oral Biol.
  • 2012 Jun;37(2):43-50.
The use of high throughput screening (HTS) in drug development is principally for the selection new drug candidates or screening of chemical toxicants. This system minimizes the experimental environment and...
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