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Xylitol stimulates saliva secretion via muscarinic receptor signaling pathway

Park E, Na HS, Jeong S, Chung J

  • Int J Oral Biol.
  • 2019 Jun;44(2):62-70.
  • doi: 10.11620/IJOB.2019.44.2.62
Xylitol is well-known to have an anti-caries effect by inhibiting the replication of cariogenic bacteria. In addition, xylitol enhances saliva secretion. However, the precise molecular mechanism of xylitol on saliva...
Effect of Garcinia mangostana L. and propolis extracts on the inhibition of inflammation and alveolar bone loss in ligature-induced periodontitis in rats

Sung SJ, Kang KM, Lee KH, Yoo SY, Kook JK, Lee DS, Yu SJ

  • Int J Oral Biol.
  • 2019 Jun;44(2):55-61.
  • doi: 10.11620/IJOB.2019.44.2.55
The purpose of this study was to evaluate the effect of mangosteen extract complex (MEC; Garcinia mangostana L. and propolis extracts) on the inhibition of inflammation and prevention of alveolar...
Melatonin inhibits nicotinic acetylcholine receptor functions in bovine chromaffin cells

Jo SH, Lee SH, Kim KT, Choi SY

  • Int J Oral Biol.
  • 2019 Jun;44(2):50-54.
  • doi: 10.11620/IJOB.2019.44.2.50
Melatonin is a neurotransmitter that modulates various physiological phenomena including regulation and maintenance of the circadian rhythm. Nicotinic acetylcholine receptors (nAChRs) play an important role in oral functions including orofacial...
Tannic acid-induced apoptosis in FaDu hypopharyngeal squamous cell carcinoma

Ta LT, Nguyen TT, Yoo H

  • Int J Oral Biol.
  • 2019 Jun;44(2):43-49.
  • doi: 10.11620/IJOB.2019.44.2.43
Tannic acid (TA) is a water-soluble polyphenol compound found in various herbal plants. We investigated the chemopreventive effects of TA on FaDu hypopharyngeal squamous carcinoma cells. In an 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide...
Role of proteases, cytokines, and growth factors in bone invasion by oral squamous cell carcinoma

Son SH, Chung WY

  • Int J Oral Biol.
  • 2019 Jun;44(2):37-42.
  • doi: 10.11620/IJOB.2019.44.2.37
Oral squamous cell carcinoma (OSCC) is the most common oral malignancy and an increasing global public health problem. OSCC frequently invades the jaw bone. OSCC-induced bone invasion has a significant...
Virulence genes of Streptococcus mutans and dental caries

You YO

  • Int J Oral Biol.
  • 2019 Jun;44(2):31-36.
  • doi: 10.11620/IJOB.2019.44.2.31
Streptococcus mutans is one of the important bacteria that forms dental biofilm and cause dental caries. Virulence genes in S. mutans can be classified into the genes involved in bacterial...

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