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Participation of Central P2X7 Receptors in CFA-induced Inflammatory Pain in the Orofacial Area of Rats

Yang KY, Kim MD, Ju JS, Kim MJ, Ahn DK

  • Int J Oral Biol.
  • 2014 Mar;39(1):49-56.
We investigated the role of central P2X receptors in inflammatory pain transmission in the orofacial area in rats. Experiments were carried out using male Sprague-Dawley rats weighing 230-280g. Complete Freund's...
Constituents Released from Streptococcus mutans Attenuate Arecoline-mediated Cytotoxicity in HGF Cells by Altering Intracellular Ca2+ Signaling

Erkhembaatar M, Oh H, Kim MS

  • Int J Oral Biol.
  • 2014 Mar;39(1):41-47.
Streptococcus mutans (S. mutans) is a facultative anaerobic bacterium mainly found in the oral cavity and is known to contribute to tooth decay and gingivitis. Recent studies on intestinal microbiota...
Beneficial Effects of Lactobacillus casei ATCC 334 on Halitosis Induced by Periodontopathogens

Lee KH, Baek DH

  • Int J Oral Biol.
  • 2014 Mar;39(1):35-40.
Halitosis is caused by consumption of certain foods or drinks and production of volatile sulfur compounds (VSCs) by periodontopathogens. VSCs-related halitosis is not easily removed using mechanical or chemical therapies...
Mechanism Underlying Curcumin-induced Apoptosis and Cell Cycle Arrest on SCC25 Human Tongue Squamous Cell Carcinoma Cell Line

Moon JB, Lee KH, Kim IR, Kim GC, Kwak HH, Park BS

  • Int J Oral Biol.
  • 2014 Mar;39(1):23-33.
Several studies have shown that curcumin, which is derived from the rhizomes of turmeric, possesses antimicrobial, antioxidant and anti-inflammatory properties. The antitumor properties of curcumin have also now been demonstrated...
Nuclear Factor-kappaB Dependent Induction of TNF-alpha and IL-1beta by the Aggregatibacter actinomycetemcomitans Lipopolysaccharide in RAW 264.7 Cells

Na HS, Jeong SY, Park MH, Kim S, Chung J

  • Int J Oral Biol.
  • 2014 Mar;39(1):15-22.
Aggregatibacter actinomycetemcomitans is an important pathogen in the development of localized aggressive periodontitis. Lipopolysaccharide (LPS) is a virulent factor of periodontal pathogens that contributes to alveolar bone loss and connective...
Incidence of Tetracycline Resistance Genes, tet(M) and tet(O), in Streptococci Isolated from Dental Plaques of Koreans

Kim YH, Lee SY

  • Int J Oral Biol.
  • 2014 Mar;39(1):9-13.
Streptococci are among the normal human microflora that populate the oral cavity. However, oral streptococci are known as a major causative agent for dental caries and bacterial endocarditis. Tetracycline is...
A Neuromedin B Receptor Blockade Inhibits the Growth of Human Oral Cancer Cells

Park HJ, Jeon JH, Kim MK, Ryu MH, Kim YD, Bae SK, Bae MK

  • Int J Oral Biol.
  • 2014 Mar;39(1):1-7.
Neuromedin B (NMB) acts as a growth factor or a morphogen and plays a role in cancer progression. Indeed, the NMB receptor (NMB-R) is overexpressed in different types of tumors....

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