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Oral Microbiota Comparison between Healthy volunteers, Periodontitis patients and Oral cancer patients

Na HS, Kim S, Choi YH, Lee JY, Chung J

  • Int J Oral Biol.
  • 2013 Dec;38(4):181-188.
The presence of distinct bacterial species is found to be dependent on age, diet, and disease. We compared the detection rate of several oral bacterial strains in a cohort of...
Effect of Xylitol on various Oral bacteria

Na HS, Kim SM, Kim S, Choi YH, Chung J

  • Int J Oral Biol.
  • 2013 Dec;38(4):175-180.
Xylitol is a five-carbon sugar alcohol that reduces the incidence of caries by inhibiting the growth of oral streptococci, including Streptococcus mutans. Since xylitol is transported via the fructose phosphotransferase...
Fast temporal detection of intracellular hydrogen peroxide by HyPer

Yang YM, Lee SJ, Shin DM

  • Int J Oral Biol.
  • 2013 Dec;38(4):169-173.
HyPer is the genetically encoded biosensor of intracellular hydrogen peroxide (H2O2), the most stable of the reactive oxygen species (ROS) generated by living cells. HyPer has a high sensitivity and...
Effects of nanoscale ridge/groovepattern arrayed surface on in vitro differentiation of multi-potent pulp cells derived from human supernumerary teeth

Kim D, Jo H, Lee J, Kim K, Roh S

  • Int J Oral Biol.
  • 2013 Dec;38(4):161-167.
Human dental pulp stem cells (DPSCs) are multi-potent mesenchymal stem cells that have several differentiation potentials. An understanding of the tissues that differentiate from these cells can provide insights for...
Cholesterol conjugated spermine as a delivery modality of antisense oligonucleotide

Im YK, Kim MS, Yoo H

  • Int J Oral Biol.
  • 2013 Dec;38(4):155-160.
The major issue in the development of nucleic acid based therapeutics is the inefficient delivery of these agents into cells. We prepared cholesterol conjugated spermine and evaluated its usefulness as...
Antimicrobial Activity of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Periodontopathogens

Park SN, Kook JK

  • Int J Oral Biol.
  • 2013 Dec;38(4):149-154.
In general, oleanolic acid (OA) and ursolic acid (UA) have antimicrobial effect against Gram-positive bacteria but not Gram-negative bacteria whereas sophoraflavanone G has antimicrobial activity against both bacterial types. However,...
Antimicrobial Activity of Berberine against Oral Bacteria Related to Endodontic Infections

Lee D, Kim MJ, Park SN, Lim YK, Min JB, Hwang HK, Kook JK

  • Int J Oral Biol.
  • 2013 Dec;38(4):141-147.
It has been established that berberine has strong antimicrobial effects. Little is known however regarding the antimicrobial activity of berberine against endodontic pathogenic bacteria or its cytotoxicity in human oral...
High dose of QX-314 produces anti-nociceptive effect without capsaicin in rats with inflammatory TMJ pain

Yang KY, Kim MS, Kim EK, Kong MS, Ahn JS, Lee JH, Ju JS, Ahn DK

  • Int J Oral Biol.
  • 2013 Dec;38(4):135-140.
The present study investigated the effects of QX-314 on inflammatory pain of the temporomandibular joint (TMJ). Experiments were carried out on male Sprague-Dawley rats weighing 220-280 g. Under anesthesia, the...

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