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9 results

MicroRNA Analysis during Cultured Odontoblast Differentiation

Park MG, Lee MH, Yu SK, Park E, Kim S, Lee SA, Moon YH, Kim HJ, Kim CS, Kim DK

  • Int J Oral Biol.
  • 2012 Sep;37(3):146-152.
MicroRNAs (miRNAs, miRs) are about 21-25 nucleotides in length and regulate mRNA translation by base pairing to partially complementary sites, predominantly in the 3'-untranslated region (3'-UTR) of the target mRNA....
Aggregatibacter actinomycetemcomitans Strongly Stimulates Endothelial Cells to Produce Monocyte Chemoattractant Protein-1 and Interleukin-8

Choi EK, Kang MS, Oh BH, Kim SY, Kim SH, Kang IC

  • Int J Oral Biol.
  • 2012 Sep;37(3):137-145.
Aggregatibacter actinomycetemcomitans is the most important etiologic agent of aggressive periodontitis and can interact with endothelial cells. Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) are chemokines, playing important roles in...
Fusobacterium nucleatum GroEL signaling via Toll-like receptor 4 in human microvascular endothelial cells

Lee HR, Choi BK

  • Int J Oral Biol.
  • 2012 Sep;37(3):130-136.
The GroEL heat-shock protein from Fusobacterium nucleatum, a periodontopathogen, activates risk factors for atherosclerosis in human microvascular endothelial cells (HMEC-1) and ApoE-/- mice. In this study, we analyzed the signaling...
Glia Dose not Participate in Antinociceptive Effects of Gabapentin in Rats with Trigeminal Neuropathic Pain

Yang KY, Kim HK, Jin MU, Ju JS, Ahn DK

  • Int J Oral Biol.
  • 2012 Sep;37(3):121-129.
Previous clinical studies have demonstrated that gabapentin, a drug that binds to the voltage-gated calcium channel alpha2delta1 subunit proteins, is effective in the management of neuropathic pain, but there is...
Retinoic Acid Increases the Cell Cycle Progression of Human Gingival Fibroblasts by Increasing Cyclin E and CDK 2 Expression and Decreasing p21WAF1/CIP1 and p16INK4A Expression

You HK, Seo SJ, Kim KJ, Choi NY, You YO

  • Int J Oral Biol.
  • 2012 Sep;37(3):115-120.
Retinoic acid plays an important role in the regulation of cell growth and differentiation. In our present study, we evaluated the effects of all-trans retinoic acid (RA) on cell proliferation...
Identification of differentially expressed genes using an annealing control primer system in periodontitis

Na HS, Kim JS, Chung J

  • Int J Oral Biol.
  • 2012 Sep;37(3):109-114.
In the gingival tissues of patients with periodontitis, inflammatory responses are mediated by a wide variety of genes. In this study, we screened for differentially expressed genes (DEGs) in periodontitis...
The Effect of Erythrosine-mediated Photodynamic Therapy on Intraorally Formed Biofilm on Titanium Surface

Park SH, Lee SY, Chang BS, Um HS, Lee JK

  • Int J Oral Biol.
  • 2012 Sep;37(3):103-108.
The purpose of this study was to assess the efficacy of photodynamic therapy (PDT) using erythrosine and a halogen light source to treat a biofilm formed on a machined surface...
HS-1200 Overcomes the Resistance Conferred by Bcl-2 in Human Leukemic U937 Cells

Park JY, Moon JB, Kim IR, Kim GC, Park BS, Kwak HH

  • Int J Oral Biol.
  • 2012 Sep;37(3):91-102.
Bcl-2 protects tumor cells from the apoptotic effects of various anti-neoplastic agents. Increased expression of Bcl-2 has been associated with a poor response to chemotherapy in various malignancies, including leukemia....
Micro-CT analysis of LPS-induced Alveolar Bone Loss in Diabetic Mice

Park HR, Park BJ

  • Int J Oral Biol.
  • 2012 Sep;37(3):85-90.
Periodontal disease induces an increased incidence of tooth loss, particularly in cases with an associated loss of alveolar bone and periodontal ligaments. In this study, alveolar bone loss was detected...

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