- Filaggrin Mutation in Korean Patients with Atopic Dermatitis
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On HR, Lee SE, Kim SE, Hong WJ, Kim HJ, Nomura T, Suzuki S, Shimizu H, Kim SC
- KMID: 2427129
- Yonsei Med J.
- 2017 Mar;58(2):395-400.
- doi: 10.3349/ymj.2017.58.2.395
PURPOSE: Atopic dermatitis (AD) is a chronic, relapsing eczematous inflammatory skin disease. Mutations in the filaggrin gene (FLG) are major predisposing factors for AD. Ethnic differences exist between Asian and... -
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- Skin Barrier Function Is Not Impaired and Kallikrein 7 Gene Polymorphism Is Frequently Observed in Korean X-linked Ichthyosis Patients Diagnosed by Fluorescence in Situ Hybridization and Array Comparative Genomic Hybridization
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Lee NR, Yoon NY, Jung M, Kim JY, Seo SJ, Wang HY, Lee H, Sohn YB, Choi EH
- KMID: 2373761
- J Korean Med Sci.
- 2016 Aug;31(8):1307-1318.
- doi: 10.3346/jkms.2016.31.8.1307
X-linked ichthyosis (XLI) is a recessively inherited ichthyosis. Skin barrier function of XLI patients reported in Western countries presented minimally abnormal or normal. Here, we evaluated the skin barrier properties... -
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- An Analysis of the Filaggrin Gene Polymorphism in Korean Atopic Dermatitis Patients
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Park KY, Li K, Seok J, Seo SJ
- KMID: 2373735
- J Korean Med Sci.
- 2016 Jul;31(7):1136-1142.
- doi: 10.3346/jkms.2016.31.7.1136
Research of the FLG mutation in various ethnic groups revealed non-overlapping mutation patterns. In addition, Japanese and Chinese atopic patients showed somewhat different mutations. These ethnic differences make the research... -
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- Mutations in the Filaggrin are Predisposing Factor in Korean Children With Atopic Dermatitis
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Yu HS, Kang MJ, Jung YH, Kim HY, Seo JH, Kim YJ, Lee SH, Kim HJ, Kwon JW, Kim BJ, Yu J, Hong SJ
- KMID: 2260314
- Allergy Asthma Immunol Res.
- 2013 Jul;5(4):211-215.
- doi: 10.4168/aair.2013.5.4.211
PURPOSE: Filaggrin (FLG) is a key protein that facilitates the terminal differentiation of the epidermis and the formation of the skin barrier. Recent studies showed that atopic dermatitis (AD) associates... -
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- Valproic Acid Increases Expression of Neuronal Stem/Progenitor Cell in Spinal Cord Injury
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Bang WS, Kim KT, Cho DC, Kim HJ, Sung JK
- KMID: 2190850
- J Korean Neurosurg Soc.
- 2013 Jul;54(1):8-13.
- doi: 10.3340/jkns.2013.54.1.8
OBJECTIVE: This study investigates the effect of valproic acid (VPA) on expression of neural stem/progenitor cells (NSPCs) in a rat spinal cord injury (SCI) model. METHODS: Adult male rats (n=24) were... -
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- Characterization of nestin expression in astrocytes in the rat hippocampal CA1 region following transient forebrain ischemia
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Cho JM, Shin YJ, Park JM, Kim J, Lee MY
- KMID: 2263105
- Anat Cell Biol.
- 2013 Jun;46(2):131-140.
- doi: 10.5115/acb.2013.46.2.131
Recent studies have suggested that nestin facilitates cellular structural remodeling in vasculature-associated cells in response to ischemic injury. The current study was designed to investigate the potential role of post-ischemic... -
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- Expression Profiles of F4/80 and Nestin in Ocular Immune Cells Following Pharmaceutically Induced Retinal Degeneration in Adult Mice
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Ahn SI, Ohn YH, Park TK
- KMID: 2217272
- J Korean Ophthalmol Soc.
- 2013 Jun;54(6):945-953.
- doi: 10.3341/jkos.2013.54.6.945
PURPOSE: To evaluate the expression patterns of F4/80 and nestin in the ciliary body and the optic nerve following N-methyl-N-nitrosourea (NMU)-induced retinal degeneration in adult mice. METHODS: After intraperitoneal injection of... -
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- Dietary effect of royal jelly supplementation on epidermal levels of hydration, filaggrins, free amino acids and the related enzyme expression in UV irradiated hairless mice
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Min J, Lee Y, Han SM, Choi Y
- KMID: 2269388
- Korean J Nutr.
- 2013 Apr;46(2):109-118.
- doi: 10.4163/kjn.2013.46.2.109
Ultraviolet (UV) irradiation reduces epidermal hydration, which is paralleled by the reduction of natural moisturizing factors (NMFs). Of various NMFs, free amino acids (AAs) are major constituents generated by filaggrin... -
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- Alpha Internexin Expression Related with Molecular Characteristics in Adult Glioblastoma and Oligodendroglioma
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Suh JH, Park CK, Park SH
- KMID: 1786969
- J Korean Med Sci.
- 2013 Apr;28(4):593-601.
- doi: 10.3346/jkms.2013.28.4.593
Alpha-internexin (INA) is a proneuronal gene-encoding neurofilament interacting protein. INA is overexpressed mostly in oligodendroglial phenotype gliomas, is related to 1p/19q codeletion, and is a favorable prognostic marker. We studied... -
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- Atopic dermatitis and skin barrier dysfunction
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Kim H, Shin JU, Lee KH
- KMID: 2263055
- Allergy Asthma Respir Dis.
- 2013 Mar;1(1):20-28.
- doi: 10.4168/aard.2013.1.1.20
Atopic dermatitis is a chronic relapsing eczematous dermatosis, which usually starts in childhood, and various causes are intricately associated with the development of the disease. Recently, various abnormalities in barrier... -
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- Distribution of Peripherin Immunoreactive Axons in Rat Molar Pulp
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Kim TH, Bae YC, Yang ES
- KMID: 1430197
- Korean J Phys Anthropol.
- 2013 Mar;26(1):33-40.
- doi: 10.11637/kjpa.2013.26.1.33
Dental pulp is innervated mostly by unmyelinated axons and small myelinated axons. These axons are implicated pain transmission and contain various neurotransmitters and receptors. However, little information, so far, is... -
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- Comparative Analysis of the Expression of Involucrin, Filaggrin and Cytokeratin 4, 10, 16 in Cholesteatoma
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Min HJ, Park CW, Jeong JH, Cho SH, Kim KR, Lee SH
- KMID: 1430729
- Korean J Audiol.
- 2012 Dec;16(3):124-129.
- doi: 10.7874/kja.2012.16.3.124
BACKGROUND AND OBJECTIVES: The aim of this study is to determine whether the hyperproliferative and hyperkeratotic characters of cholesteatoma are associated with differentiation of keratinocytes in cholesteatoma by examining the... -
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- Allergic March: Progression from Atopic Dermatitis to Asthma
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- KMID: 2299462
- Korean J Asthma Allergy Clin Immunol.
- 2012 Sep;32(3):137-143.
Allergic march is progression of allergic disorders from atopic dermatitis in infancy to asthma or allergic rhinitis later. Most prospective epidemiologic studies suggest that early atopic dermatitis is a risk... -
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- Neurochemical Properties of Dental Primary Afferent Neurons
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Vang H, Chung G, Kim HY, Park SB, Jung SJ, Kim JS, Oh SB
- KMID: 1438551
- Exp Neurobiol.
- 2012 Jun;21(2):68-74.
- doi: 10.5607/en.2012.21.2.68
The long belief that dental primary afferent (DPA) neurons are entirely composed of nociceptive neurons has been challenged by several anatomical and functional investigations. In order to characterize non-nociceptivepopulation among... -
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- Histologic morphology and involucrin, filaggrin, and keratin expression in normal canine skin from dogs of different breeds and coat types
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Theerawatanasirikul S, Suriyaphol G, Thanawongnuwech R, Sailasuta
- KMID: 1376190
- J Vet Sci.
- 2012 Jun;13(2):163-170.
- doi: 10.4142/jvs.2012.13.2.163
The purpose of this study was to measure the thickness of canine epidermis at various anatomical sites according to localization of cornified envelopes (involucrin and filaggrin), keratins (keratin 10, 5),... -
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- Nestin expressing progenitor cells during establishment of the neural retina and its vasculature
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Lee JH, Park HS, Shin JM, Chun MH, Oh SJ
- KMID: 1447451
- Anat Cell Biol.
- 2012 Mar;45(1):38-46.
- doi: 10.5115/acb.2012.45.1.38
In order to test if nestin is a useful marker for various types of progenitor cells, we explored nestin expression in the retina during development. Nestin expression was co-evaluated with... -
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- Epidermal Barrier in Atopic Dermatitis
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Kim BE, Leung DY
- KMID: 2130373
- Allergy Asthma Immunol Res.
- 2012 Jan;4(1):12-16.
- doi: 10.4168/aair.2012.4.1.12
Atopic dermatitis (AD) is a complex disease that affects up to 20% of children and impacts the quality of patients and families in a significant manner. New insights into the... -
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- Effect of Gestational Exposure to Bisphenol A on Neuronal Stem Cell Differentiation in the Neonatal Rat Hippocampus
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Wang SW, Kim JM, Hwang KG
- KMID: 2329485
- J Korean Child Neurol Soc.
- 2011 Dec;19(3):218-230.
PURPOSE: Neurogenesis in neonatal period after birth occurs consequently through a series of neuronal stem/progenitor cell proliferation and differentiation. This stage is critical for determining of normal development and maturation... -
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- Stem Cell Dynamics in an Experimental Model of Stroke
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Lee MC, Jin CY, Kim HS, Kim JH, Kim MK, Kim HI, Lee YJ, Son YJ, Kim YO, Woo YJ
- KMID: 2048791
- Chonnam Med J.
- 2011 Aug;47(2):90-98.
- doi: 10.4068/cmj.2011.47.2.90
We investigated the migration of endogenous neural stem cells (NSCs) toward an infarct lesion in a photo-thrombotic stroke model. The lesions produced by using rose bengal dye (20 mg/kg) with... -
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- Genetic Polymorphism of FLG in Korean Ichthyosis Vulgaris Patients
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Kim EJ, Jeong MS, Li K, Park MK, Lee MK, Yoon Y, Cho DY, Seo SJ
- KMID: 2156658
- Ann Dermatol.
- 2011 May;23(2):170-176.
- doi: 10.5021/ad.2011.23.2.170
BACKGROUND: Filaggrin is a key protein that facilitates the formation of skin barrier by forming a stratum corneum. Mutations in the gene encoding filaggrin (FLG) have recently been reported in... -
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