- Circulating MicroRNAs and T-Cell Cytokine Expression Are Associated With the Characteristics of Asthma Exacerbation
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Wardzyńska A, Pawełczyk M, Rywaniak J, Kurowski M, Makowska J, Kowalski M
- KMID: 2462577
- Allergy Asthma Immunol Res.
- 2020 Jan;12(1):125-136.
- doi: 10.4168/aair.2020.12.1.125
PURPOSE: Immunological mechanisms underlying asthma exacerbation have not been elucidated. The aim of this study was to assess the associations of various asthma exacerbation traits with selected serum microRNA (miRNA)... -
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- Therapeutic Effect of Glucosamine on an Atopic Dermatitis Animal Model
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Yoon HS, Byun JW, Shin J, Kim YH, Choi GS
- KMID: 2456231
- Ann Dermatol.
- 2019 Oct;31(5):538-544.
- doi: 10.5021/ad.2019.31.5.538
BACKGROUND: Recent studies have reported that glucosamine (GlcN) showed therapeutic effects in allergic diseases such as asthma and rhinitis, and its mechanisms include the suppression of T helper type 2... -
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- Dioscorea japonica Thunb. Ethanolic Extract Attenuated Oxazolone-Induced Atopic Dermatitis-like Skin Lesions in BALB/c Mice
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Jegal J, Park NJ, Jo BG, Kim SN, Yang MH
- KMID: 2459970
- Nat Prod Sci.
- 2019 Sep;25(3):261-267.
- doi: 10.20307/nps.2019.25.3.261
The rhizomes of Dioscorea japonica Thunb. are widely consumed as food and also used to treat diabetes and polyuria in Korea. This study was undertaken to study the anti-atopic dermatitis... -
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- Short-term Haze Exposure Predisposes Healthy Volunteers to Nasal Inflammation
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Xian M, Wang K, Lou H, Wang Y, Zhang L, Wang C
- KMID: 2452754
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):632-643.
- doi: 10.4168/aair.2019.11.5.632
PURPOSE: This study aimed to investigate the impact of short-term haze exposure on nasal inflammation in healthy volunteers. METHODS: Thirty-three healthy university students were assessed for nasal symptoms, nasal patency, upper... -
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- Distinct Inflammation Biomarkers in Healthy Individuals and Patients with Schizophrenia: A Reliability Testing of Multiplex Cytokine Immunoassay by Bland-Altman Analysis
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Yeh TC, Chu HT, Tsai CK, Chang HA, Yang FC, Huang SY, Liang CS
- KMID: 2456171
- Psychiatry Investig.
- 2019 Aug;16(8):607-614.
- doi: 10.30773/pi.2019.04.14
OBJECTIVE: Since the inflammatory process has been implicated in the pathophysiology of psychiatric disorder, an important issue emerging is to assess the test-retest reliability of cytokine measurement in healthy individuals... -
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- Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells
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Choi N, Sung JH
- KMID: 2455096
- Biomol Ther.
- 2019 Jul;27(4):404-413.
- doi: 10.4062/biomolther.2018.195
Udenafil, which is a PDE5 inhibitor, is used to treat erectile dysfunction. However, it is unclear whether udenafil induces hair growth via the stimulation of adipose-derived stem cells (ASCs). In... -
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- Antiallergic Effect of Hizikia fusiformis in an Ovalbumin-Induced Allergic Rhinitis Mouse Model
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Zhang YL, Shin HJ, Lee JH, Lee J
- KMID: 2447429
- Clin Exp Otorhinolaryngol.
- 2019 May;12(2):196-205.
- doi: 10.21053/ceo.2019.00094
OBJECTIVES: The extract of Hizikia fusiformis is known to exhibit anticancer, antiatopic and antioxidant activities. We aimed to investigate the extract of H. fusiformis on allergic rhinitis inflammation in a... -
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- Production of Inflammatory Cytokines and Nitric Oxide by Human Mast Cells Incubated with Toxoplasma gondii Lysate
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Park EA, Han IH, Kim JH, Park SJ, Ryu JS, Ahn MH
- KMID: 2448154
- Korean J Parasitol.
- 2019 Apr;57(2):201-206.
- doi: 10.3347/kjp.2019.57.2.201
The roles of mast cells in allergic diseases and helminth infections are well known. However, the roles of mast cells in T. gondii infection is poorly understood. This study was... -
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- Peripheral Biomarkers for First-Episode Psychosis—Opportunities from the Neuroinflammatory Hypothesis of Schizophrenia
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Trovão N, Prata J, VonDoellinger O, Santos S, Barbosa M, Coelho R
- KMID: 2447256
- Psychiatry Investig.
- 2019 Mar;16(3):177-184.
- doi: 10.30773/pi.2018.12.19.1
OBJECTIVE: Schizophrenia is a disabling disorder of unknown aetiology, lacking definite diagnostic method and cure. A reliable biological marker of schizophrenia is highly demanded, for which traceable immune mediators in... -
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- Intranasal Treatment With 1, 25-Dihydroxyvitamin D3 Alleviates Allergic Rhinitis Symptoms in a Mouse Model
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Cho SW, Zhang YL, Ko YK, Shin JM, Lee JH, Rhee CS, Kim DY
- KMID: 2431858
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):267-279.
- doi: 10.4168/aair.2019.11.2.267
PURPOSE: Vitamin D is a potent immunomodulator. However, its role in the pathogenesis of allergic rhinitis is unclear. METHODS: The aim of this study was to evaluate the antiallergic effect of... -
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- N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis
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Kim HR, Kim KW, Kim BM, Lee KA, Lee SH
- KMID: 2452505
- Korean J Intern Med.
- 2019 Jan;34(1):210-219.
- doi: 10.3904/kjim.2016.329
BACKGROUND/AIMS: This study aimed to determine the regulatory role of N-acetyl-l-cysteine (NAC), an antioxidant, in interleukin 17 (IL-17)-induced osteoclast differentiation in rheumatoid arthritis (RA). METHODS: After RA synovial fibroblasts were stimulated... -
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- From Bench to Clinic: the Potential of Therapeutic Targeting of the IL-22 Signaling Pathway in Atopic Dermatitis
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Jin M, Yoon J
- KMID: 2429834
- Immune Netw.
- 2018 Dec;18(6):e42.
- doi: 10.4110/in.2018.18.e42
Atopic dermatitis (AD) is the most common pruritic inflammatory skin disease characterized by thickening of epidermis and dermis as well as by the infiltration of multiple pathogenic polarized T lymphocytes,... -
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- Mucosal Immunity Related to FOXP3⺠Regulatory T Cells, Th17 Cells and Cytokines in Pediatric Inflammatory Bowel Disease
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Cho J, Kim S, Yang DH, Lee J, Park KW, Go J, Hyun CL, Jee Y, Kang KS
- KMID: 2429597
- J Korean Med Sci.
- 2018 Dec;33(52):e336.
- doi: 10.3346/jkms.2018.33.e336
BACKGROUND: We aimed to investigate mucosal immunity related to forkhead box P3 (FOXP3+) regulatory T (Treg) cells, T helper 17 (Th17) cells and cytokines in pediatric inflammatory bowel disease (IBD). METHODS:... -
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- The Effect of Adiponectin on the Regulation of Filaggrin Expression in Normal Human Epidermal Keratinocytes
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Choi SY, Kim MJ, Ahn GR, Park KY, Lee MK, Seo SJ
- KMID: 2428919
- Ann Dermatol.
- 2018 Dec;30(6):645-652.
- doi: 10.5021/ad.2018.30.6.645
BACKGROUND: Adiponectin, an adipokine secreted from adipocytes, affects energy metabolism and also shows anti-diabetic and anti-inflammatory properties. Recent studies have reported that adiponectin plays a role in regulating skin inflammation. OBJECTIVE:... -
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- Bcl11b Regulates IL-17 Through the TGF-β/Smad Pathway in HDM-Induced Asthma
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Chen S, Han Y, Chen H, Wu J, Zhang M
- KMID: 2418051
- Allergy Asthma Immunol Res.
- 2018 Sep;10(5):543-554.
- doi: 10.4168/aair.2018.10.5.543
PURPOSE: T helper (Th) 17 cells play a critical role in the development of asthma, but the underlying mechanism of how interleukin (IL)-17 is regulated in allergic airway inflammation is... -
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- Lactobacillus plantarum-derived Extracellular Vesicles Protect Atopic Dermatitis Induced by Staphylococcus aureus-derived Extracellular Vesicles
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Kim MH, Choi SJ, Choi HI, Choi JP, Park HK, Kim EK, Kim MJ, Moon BS, Min TK, Rho M, Cho YJ, Yang S, Kim YK, Kim YY, Pyun BY
- KMID: 2418049
- Allergy Asthma Immunol Res.
- 2018 Sep;10(5):516-532.
- doi: 10.4168/aair.2018.10.5.516
PURPOSE: The microbial environment is an important factor that contributes to the pathogenesis of atopic dermatitis (AD). Recently, it was revealed that not only bacteria itself but also extracellular vesicles... -
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- Association between an Interleukin 4 Gene Polymorphism, rs2243268, and Urogenital Tuberculosis
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Shim B, Lee SD, Kim TH, Jung SI, Cho WY, Lee G
- KMID: 2419780
- Urogenit Tract Infect.
- 2018 Aug;13(2):35-39.
- doi: 10.14777/uti.2018.13.2.35
PURPOSE: Urogenital tuberculosis (UGT) is rarely reported in developed countries. This study evaluated the genetic susceptibility of Korean patients to UGT. MATERIALS AND METHODS: A total of 35 UGT patients who... -
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- Thapsigargin Increases IL-2 Production in T Cells at Nanomolar Concentrations
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Kim KH, Kim SH, Jung HH, Moon JH, Jeong SU, Yu K, Lee CK
- KMID: 2419771
- Immune Netw.
- 2018 Aug;18(4):e26.
- doi: 10.4110/in.2018.18.e26
Thapsigargin (TGN) is a potent and selective inhibitor of sarco-endoplasmic Ca²âº-ATPase, leading to rapid elevation of cytoplasmic Ca2+ concentration. Previous reports have shown that TGN increases the production of various... -
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- Interleukin-4 Contributes to Degeneration of Dopamine Neurons in the Lipopolysaccharide-treated Substantia Nigra in vivo
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Bok E, Cho EJ, Chung ES, Shin WH, Jin BK
- KMID: 2419340
- Exp Neurobiol.
- 2018 Aug;27(4):309-319.
- doi: 10.5607/en.2018.27.4.309
The present study investigated the effects of interleukin (IL)-4 on dopamine (DA) neurons in the substantia nigra (SN) in vivo of lipopolysaccharide (LPS)-treated rat. Tyrosine hydroxylase immunohistochemistry showed a significant... -
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- Tolerogenic Dendritic Cells Reduce Airway Inflammation in a Model of Dust Mite Triggered Allergic Inflammation
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Aragão-França LS, Rocha VC, Cronemberger-Andrade A, Costa FH, Vasconcelos JF, Athanazio , Silva DN, Santos ES, Meira CS, Araújo CF, Cerqueira , Cardillo F, Alcântara-Neves NM, Soares MB, Pontes-de-Carvalho LC
- KMID: 2421675
- Allergy Asthma Immunol Res.
- 2018 Jul;10(4):406-419.
- doi: 10.4168/aair.2018.10.4.406
PURPOSE: The use of tolerogenic dendritic cells (TolDCs) to control exacerbated immune responses may be a prophylactic and therapeutic option for application in autoimmune and allergic conditions. The objective of... -
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