- Increased Expression of Interleukin-12 in Lesional Skin of Atopic Dermatitis Patients with Psoriasiform Features on Histopathology: An Immunohistochemical Study
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Lim HJ, Han MH, Lee EH, Eun DH, Kim JY, Lee WJ, Lee SJ, Kim DW, Park TI, Kim SH, Jang YH
- KMID: 2467198
- Ann Dermatol.
- 2020 Feb;32(1):31-37.
- doi: 10.5021/ad.2020.32.1.31
BACKGROUND: Based on clinical and genetic differences, atopic dermatitis (AD) and psoriasis have been classified in two different diseases, but recently, some authors regarded them as in one spectrum. The... -
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- Antileishmanial Activity of Niosomal Combination Forms of Tioxolone along with Benzoxonium Chloride against Leishmania tropica
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Parizi MH, Farajzadeh S, Sharifi I, Pardakhty , Parizi MH, Sharifi H, Salarkia E, Hassanzadeh S
- KMID: 2459473
- Korean J Parasitol.
- 2019 Aug;57(4):359-368.
- doi: 10.3347/kjp.2019.57.4.359
In this study, we carried out extensive in vitro studies on various concentrations of tioxolone along with benzoxonium chloride and their niosomal forms against Leishmania tropica. Niosomes were prepared by... -
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- Distinct Inflammation Biomarkers in Healthy Individuals and Patients with Schizophrenia: A Reliability Testing of Multiplex Cytokine Immunoassay by Bland-Altman Analysis
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Yeh TC, Chu HT, Tsai CK, Chang HA, Yang FC, Huang SY, Liang CS
- KMID: 2456171
- Psychiatry Investig.
- 2019 Aug;16(8):607-614.
- doi: 10.30773/pi.2019.04.14
OBJECTIVE: Since the inflammatory process has been implicated in the pathophysiology of psychiatric disorder, an important issue emerging is to assess the test-retest reliability of cytokine measurement in healthy individuals... -
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- Mycobacterium tuberculosis ESAT6 Drives the Activation and Maturation of Bone Marrow-Derived Dendritic Cells via TLR4-Mediated Signaling
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Jang AR, Kim G, Hong JJ, Kang SM, Shin SJ, Park JH
- KMID: 2444161
- Immune Netw.
- 2019 Apr;19(2):e13.
- doi: 10.4110/in.2019.19.e13
6-kDa early secretory antigenic target (ESAT6), a virulent factor of Mycobacterium tuberculosis, is involved in immune regulation. However, the underlying mechanism behind the activation and maturation of dendritic cells (DCs)... -
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- A Novel Niosomal Combination of Selenium Coupled with Glucantime against Leishmania tropica
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Mostafavi , Khazaeli P, Sharifi I, Farajzadeh S, Sharifi H, Keyhani A, Parizi MH, Kakooei S
- KMID: 2441599
- Korean J Parasitol.
- 2019 Feb;57(1):1-8.
- doi: 10.3347/kjp.2019.57.1.1
There is no effective treatment modality available against different forms of leishmaniasis. Therefore, the aim of this study was to improve the penetration and efficacy of selenium and glucantime coupled... -
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- IL-12 Enhances Immune Response by Modulation of Myeloid Derived Suppressor Cells in Tumor Microenvironment
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Choi JN, Sun EG, Cho SH
- KMID: 2432253
- Chonnam Med J.
- 2019 Jan;55(1):31-39.
- doi: 10.4068/cmj.2019.55.1.31
Myeloid derived suppressor cells (MDSCs) are a heterogenous population of immature cells that play a critical role in tumor associated immune suppression. In tumor conditions, the population of MDSCs increases.... -
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- The immune enhancing effects and characteristics of Bifidobacterium longum and Bifidobacterium breve for the probiotic use in humans and animals
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Park HE, Um HB, Lee WK
- KMID: 2435741
- J Biomed Transl Res.
- 2018 Dec;19(4):65-72.
- doi: 10.12729/jbtr.2018.19.4.065
The purpose of this study was to investigate probiotic characteristics and immune enhancing effects of Bifidobacterium (B.) longum KBB1-26 and BIF-4, B. breve KBB5-22 isolated from human intestine for probiotic... -
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- A Case of Paradoxical Flare of Pustular Psoriasis after Ustekinumab Therapy
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Kang IH, Shin MK, Lee MH, Jeong KH
- KMID: 2436996
- Korean J Dermatol.
- 2018 Nov;56(9):548-551.
Biologics are the most advanced treatment for psoriasis. Ustekinumab, one of the biologics for psoriasis, is a human monoclonal antibody that binds to the p40 subunit of interleukin-12 and interleukin-23.... -
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- Evaluation of Protective Immune Response Induced by a DNA Vaccine Encoding GRA8 against Acute Toxoplasmosis in a Murine Model
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Chu JQ, Huang S, Ye W, Fan XY, Huang R, Ye SC, Yu CY, Wu WY, Zhou Y, Zhou W, Lee YH, Quan JH
- KMID: 2420316
- Korean J Parasitol.
- 2018 Aug;56(4):325-334.
- doi: 10.3347/kjp.2018.56.4.325
Toxoplasma gondii is an apicomplexan zoonotic protozoan parasite that infects most species of warm-blooded animals, including humans. The heavy incidence and severe or lethal damage caused by T. gondii infection... -
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- Marek's disease vaccine activates chicken macrophages
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Wang D, Sun S, Heidari M
- KMID: 2412128
- J Vet Sci.
- 2018 May;19(3):375-383.
- doi: 10.4142/jvs.2018.19.3.375
To provide insights into the role of innate immune responses in vaccine-mediated protection, we investigated the effect of Marek's disease (MD) vaccine, CVI988/Rispens, on the expression patterns of selected genes... -
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- Can the Cytokine Analysis of the Scales on Alopecic Patch Predict the Response to Diphenylcyclopropenone Treatment in Alopecia Areata Patients?
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Lee SH, Moon JH, Ban DH, Byun JW, Shin J, Choi GS
- KMID: 2414675
- Ann Dermatol.
- 2018 Apr;30(2):150-157.
- doi: 10.5021/ad.2018.30.2.150
BACKGROUND: Contact immune modulating therapy with diphenylcyclopropenone (DPCP) is a topical treatment option for extensive alopecia areata (AA). Because the response to DPCP treatment varies according to the patient, and... -
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- Alterations in Spontaneous Movement, Corticosterone, and Cytokines in Mice Exposed to 835 MHz Radiofrequency Radiation
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Lee MS, Oh CS, Ryu JH, Lee JK, Kim MJ
- KMID: 2408314
- Korean J Phys Anthropol.
- 2018 Mar;31(1):19-26.
- doi: 10.11637/kjpa.2018.31.1.19
Although commercialization of mobile phones has raised much concerns about the effects of radiofrequency radiation on the human body, few experimental studies have been conducted on the effects of radiofrequency... -
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- Emerging Therapies: What Are Promising in the Near Future?
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Seo GS, Lee SH
- KMID: 2405000
- Korean J Gastroenterol.
- 2018 Feb;71(2):81-88.
- doi: 10.4166/kjg.2018.71.2.81
The treatment of inflammatory bowel disease has evolved with the development of anti-TNF agents. In spite of long-term effectiveness, many patients do not respond or no longer responds to these... -
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- Regulation of Osteoclast Differentiation by Cytokine Networks
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Amarasekara DS, Yun H, Kim S, Lee N, Kim H, Rho J
- KMID: 2404891
- Immune Netw.
- 2018 Feb;18(1):e8.
- doi: 10.4110/in.2018.18.e8
Cytokines play a pivotal role in maintaining bone homeostasis. Osteoclasts (OCs), the sole bone resorbing cells, are regulated by numerous cytokines. Macrophage colony-stimulating factor and receptor activator of NF-κB ligand... -
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- IL-12 and IL-23 Production in Toxoplasma gondii- or LPS-Treated Jurkat T Cells via PI3K and MAPK Signaling Pathways
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Ismail HA, Kang BH, Kim JS, Lee JH, Choi IW, Cha GH, Yuk JM, Lee YH
- KMID: 2403712
- Korean J Parasitol.
- 2017 Dec;55(6):613-622.
- doi: 10.3347/kjp.2017.55.6.613
IL-12 and IL-23 are closely related in structure, and have been shown to play crucial roles in regulation of immune responses. However, little is known about the regulation of these... -
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- Therapeutic Effects of Resiniferatoxin Related with Immunological Responses for Intestinal Inflammation in Trichinellosis
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Muñoz-Carrillo JL, Muñoz-López JL, Muñoz-Escobedo JJ, Maldonado-Tapia C, Gutiérrez-Coronado O, Contreras-Cordero JF, Moreno-GarcÃa MA
- KMID: 2403709
- Korean J Parasitol.
- 2017 Dec;55(6):587-599.
- doi: 10.3347/kjp.2017.55.6.587
The immune response against Trichinella spiralis at the intestinal level depends on the CD4⺠T cells, which can both suppress or promote the inflammatory response through the synthesis of diverse... -
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- Saprolegnia parasitica Isolated from Rainbow Trout in Korea: Characterization, Anti-Saprolegnia Activity and Host Pathogen Interaction in Zebrafish Disease Model
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Shin S, Kulatunga , Dananjaya , Nikapitiya C, Lee J, De Zoysa M
- KMID: 2401059
- Mycobiology.
- 2017 Dec;45(4):297-311.
- doi: 10.5941/MYCO.2017.45.4.297
Saprolegniasis is one of the most devastating oomycete diseases in freshwater fish which is caused by species in the genus Saprolegnia including Saprolegnia parasitica. In this study, we isolated the... -
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- Inhibition of Lipopolysaccharide-stimulated Inflammatory Cytokine Production by LY303511 in Human Macrophagic THP-1 Cells
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Kim SH, Paek YW, Kang IC
- KMID: 2394580
- Int J Oral Biol.
- 2017 Sep;42(3):117-121.
- doi: 10.11620/IJOB.2017.42.3.117
We have previously shown that the specific phosphatidylinositol 3-kinase inhibitor LY294002 (LY29), and its inactive analog LY303511 (LY30), inhibit a monocyte chemoattractant protein-1 (MCP-1) expression in human umbilical vein endothelial... -
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- Comparison of cytokine expression profiles in infants with a rhinovirus induced lower respiratory tract infection with or without wheezing: a comparison with respiratory syncytial virus
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Roh DE, Park SH, Choi HJ, Kim YH
- KMID: 2390498
- Korean J Pediatr.
- 2017 Sep;60(9):296-301.
- doi: 10.3345/kjp.2017.60.9.296
PURPOSE: The aim of this study was to evaluate whether infants with rhinovirus (RV) infection-induced wheezing and those with respiratory syncytial virus (RSV) infection-induced wheezing have different cytokine profiles in... -
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- Gene Expression Analysis of Inflammatory Cytokines in Korean Psoriatic Patients
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Chun JH, Yoon YH, Choe YB, Kang LH, Paik SY, Park CJ
- KMID: 2388939
- Ann Dermatol.
- 2017 Aug;29(4):422-426.
- doi: 10.5021/ad.2017.29.4.422
BACKGROUND: Although phenotypic heterogeneity of psoriasis is suggested by the alternate activation of either T-helper (Th)1-related or Th17-related cytokines, little is known about the mRNA levels of inflammatory cytokines. OBJECTIVE: To... -
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