- Examination of protective and therapeutic effects of ruscogenin on cerulein-induced experimental acute pancreatitis in rats
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Ercan G, Ä°lbar Tartar R, Solmaz A, Gulcicek O, Karagulle , Meric S, Cayoren H, Kusaslan R, Kemik A, Gokceoglu Kayali D, Cetinel S, Celik A
- KMID: 2464782
- Ann Surg Treat Res.
- 2019 Dec;97(6):271-281.
- doi: 10.4174/astr.2019.97.6.271
PURPOSE: To determine the potential protective and therapeutic effects and action mechanism of ruscogenin on cerulein-induced acute pancreatitis (AP) model in rats. METHODS: Overall, 32 rats were attenuated to the sham... -
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- Adipose-Derived Stem Cell Transplantation Inhibits Vascular Inflammatory Responses and Endothelial Dysfunction in Rats with Atherosclerosis
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Fan M, Bai J, Ding T, Yang X, Si Q, Nie D
- KMID: 2460220
- Yonsei Med J.
- 2019 Nov;60(11):1036-1044.
- doi: 10.3349/ymj.2019.60.11.1036
PURPOSE: This study aimed to investigate the effect of adipose-derived stem cell (ADSC) transplantation on atherosclerosis (AS) and its underlying mechanisms. MATERIALS AND METHODS: In our study, rat AS model was... -
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- Selective inhibition of histone deacetylase 8 improves vascular hypertrophy, relaxation, and inflammation in angiotensin II hypertensive mice
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Kee HJ, Ryu Y, Seok YM, Choi SY, Sun S, Kim GR, Jeong MH
- KMID: 2468620
- Clin Hypertens.
- 2019 ;25(1):13.
- doi: 10.1186/s40885-019-0118-8
BACKGROUND: The dysregulation of histone deacetylase (HDAC) protein expression or its enzyme activity is implicated in a variety of diseases. Cardiac HDAC6 and HDAC8 enzyme activity induced by deoxycorticosterone acetate... -
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- Effects of hyperbaric oxygen and iloprost on intestinal ischemia-reperfusion induced acute lung injury
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Yilmaz Y, Tumkaya L
- KMID: 2429752
- Ann Surg Treat Res.
- 2019 Jan;96(1):34-40.
- doi: 10.4174/astr.2019.96.1.34
PURPOSE: To research the effects of iloprost (IL) and hyperbaric oxygen (HBO) combination treatment on lung injury and on tumor necrosis factor alpha (TNF-α), myeloperoxidase (MPO), malondialdehyde (MDA), and soluble... -
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- Association between the simultaneous decrease in the levels of soluble vascular cell adhesion molecule-1 and S100 protein and good neurological outcomes in cardiac arrest survivors
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Kim MJ, Kim T, Suh GJ, Kwon WY, Kim KS, Jung YS, Ko JI, Shin SM, Lee AR
- KMID: 2433157
- Clin Exp Emerg Med.
- 2018 Dec;5(4):211-218.
- doi: 10.15441/ceem.17.267
OBJECTIVE: This study aimed to determine whether simultaneous decreases in the serum levels of cell adhesion molecules (intracellular cell adhesion molecule-1 [ICAM-1], vascular cell adhesion molecule-1 [VCAM-1], and E-selectin) and... -
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- Infection of human intestinal epithelial cells by invasive bacteria activates NF-κB and increases ICAM-1 expression through NOD1
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Shin WG, Park BJ, Lee SJ, Kim JG
- KMID: 2411512
- Korean J Intern Med.
- 2018 Jan;33(1):81-90.
- doi: 10.3904/kjim.2015.409
BACKGROUND/AIMS: Nucleotide-binding oligomerization domain 1 (NOD1) is required for primary intestinal epithelial cells (IECs) to respond to natural mucopeptides secreted by gram-negative bacteria. Infection of human IECs with invasive bacteria... -
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- Protective Effect of Allium tuberosum Extract on Vascular Inflammation in Tumor Necrosis Factor-α-induced Human Vascular Endothelial Cells
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Hur HJ, Lee AS
- KMID: 2434284
- J Cancer Prev.
- 2017 Dec;22(4):228-233.
- doi: 10.15430/JCP.2017.22.4.228
BACKGROUND: Endothelial adhesion molecule expression induced by pro-inflammatory cytokine plays an important role in vascular endothelial cell injury, leading to vascular disease. Allium tuberosum (AT), which is used as a... -
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- Fate of Neutrophils during the Recovery Phase of Ischemia/Reperfusion Induced Acute Kidney Injury
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Cho W, Song JY, Oh SW, Kim MG, Ko YS, Lee HY, Jo SK
- KMID: 2400433
- J Korean Med Sci.
- 2017 Oct;32(10):1616-1625.
- doi: 10.3346/jkms.2017.32.10.1616
Effective clearance of inflammatory cells is required for resolution of inflammation. Here, we show in vivo evidence that apoptosis and reverse transendothelial migration (rTEM) are important mechanisms in eliminating neutrophils... -
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- Protein kinase C beta II upregulates intercellular adhesion molecule-1 via mitochondrial activation in cultured endothelial cells
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Joo HK, Lee YR, Choi S, Park MS, Kang G, Kim CS, Jeon BH
- KMID: 2384451
- Korean J Physiol Pharmacol.
- 2017 Jul;21(4):377-384.
- doi: 10.4196/kjpp.2017.21.4.377
Activation of protein kinase C (PKC) is closely linked with endothelial dysfunction. However, the effect of PKCβII on endothelial dysfunction has not been characterized in cultured endothelial cells. Here, using... -
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- Impact of high serum Immunoglobulin E levels on the risk of atherosclerosis in humans
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Unal D, Gelincik A, Elitok A, Demir S, Olgac M, Coskun R, Kocaaga M, Colakoglu , Buyukozturk S
- KMID: 2396928
- Asia Pac Allergy.
- 2017 Apr;7(2):74-81.
- doi: 10.5415/apallergy.2017.7.2.74
BACKGROUND: Epidemiological studies show that immunoglobulin E (IgE) levels were higher in subjects with acute coronary events. However, it is unknown if the increased IgE level is a marker of... -
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- Vascular Cell Adhesion Molecule 1, Intercellular Adhesion Molecule 1, and Cluster of Differentiation 146 Levels in Patients with Type 2 Diabetes with Complications
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Hocaoglu-Emre FS, Saribal D, Yenmis G, Guvenen G
- KMID: 2413293
- Endocrinol Metab.
- 2017 Mar;32(1):99-105.
- doi: 10.3803/EnM.2017.32.1.99
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a multisystemic, chronic disease accompanied by microvascular complications involving various complicated mechanisms. Intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1),... -
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- Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis
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Wee JH, Zhang YL, Rhee CS, Kim DY
- KMID: 2355895
- Allergy Asthma Immunol Res.
- 2017 Jan;9(1):61-69.
- doi: 10.4168/aair.2017.9.1.61
PURPOSE: It remains unknown whether local inhibition of Nuclear factor-kappa B (NF-κB) could have therapeutic value in the treatment of allergic rhinitis (AR). This study aimed to evaluate the effect... -
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- Beneficial effects of tonsillectomy plus steroid pulse therapy on inflammatory and tubular markers in patients with IgA nephropathy
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Maruyama S, Gohda T, Suzuki Y, Suzuki H, Sonoda Y, Ichikawa S, Li Z, Murakoshi , Horikoshi , Tomino Y
- KMID: 2364288
- Kidney Res Clin Pract.
- 2016 Dec;35(4):233-236.
- doi: 10.1016/j.krcp.2016.09.002
BACKGROUND: IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide. Tonsillectomy plus steroid pulse therapy has been able to induce clinical remission in early-stage IgAN. However, its... -
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- NDRG2 Expression Decreases Tumor-Induced Osteoclast Differentiation by Down-regulating ICAM1 in Breast Cancer Cells
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Kim B, Nam S, Lim JH, Lim JS
- KMID: 2170535
- Biomol Ther.
- 2016 Jan;24(1):9-18.
- doi: 10.4062/biomolther.2015.105
Bone matrix is properly maintained by osteoclasts and osteoblasts. In the tumor microenvironment, osteoclasts are increasingly differentiated by the various ligands and cytokines secreted from the metastasized cancer cells at... -
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- Effects of Local Pancreatic Renin-Angiotensin System on the Microcirculation of Rat with Severe Acute Pancreatitis
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Pan Z, Feng L, Long H, Wang H, Feng J, Chen F
- KMID: 2285572
- Korean J Physiol Pharmacol.
- 2015 Jul;19(4):299-307.
- doi: 10.4196/kjpp.2015.19.4.299
Severe acute pancreatitis (SAP) is normally related to multiorgan dysfunction and local complications. Studies have found that local pancreatic renin-angiotensin system (RAS) was significantly upregulated in drug-induced SAP. The present... -
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- Nafamostat Mesilate Inhibits TNF-alpha-Induced Vascular Endothelial Cell Dysfunction by Inhibiting Reactive Oxygen Species Production
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Kang MW, Song HJ, Kang SK, Kim Y, Jung SB, Jee S, Moon JY, Suh KS, Lee SD, Jeon BH, Kim CS
- KMID: 1791423
- Korean J Physiol Pharmacol.
- 2015 May;19(3):229-234.
- doi: 10.4196/kjpp.2015.19.3.229
Nafamostat mesilate (NM) is a serine protease inhibitor with anticoagulant and anti-inflammatory effects. NM has been used in Asia for anticoagulation during extracorporeal circulation in patients undergoing continuous renal replacement... -
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- Umbilical Cord Blood Matrix Metalloproteinase-9 Levels are associated with Funisitis
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Shim SS, Kang HS, Maeng YH, Kim YD
- KMID: 2072338
- Korean J Perinatol.
- 2015 Mar;26(1):58-66.
- doi: 10.14734/kjp.2015.26.1.58
PURPOSE: Intrauterine inflammation (IUI) is a leading cause of preterm delivery. Although matrix metalloproteinase-8 (MMP-8) and intercellular adhesion molecule-1 (ICAM-1) are known to be related with IUI, it has not... -
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- Synergistic Inhibition of Tumor Necrosis Factor-Alpha-Stimulated Pro-Inflammatory Cytokine Expression in HaCaT Cells by a Combination of Rapamycin and Mycophenolic Acid
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Kim MY, Lim YY, Kim HM, Park YM, Kang H, Kim BJ
- KMID: 2264834
- Ann Dermatol.
- 2015 Feb;27(1):32-39.
- doi: 10.5021/ad.2015.27.1.32
BACKGROUND: Keratinocytes release various pro-inflammatory cytokines, chemokines, and adhesion molecules such as intercellular adhesion molecule 1 (ICAM-1) in response to cytokines such as tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma.... -
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- Serum Levels of IL-8 and ICAM-1 as Biomarkers for Progressive Massive Fibrosis in Coal Workers' Pneumoconiosis
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Lee JS, Shin JH, Choi BS
- KMID: 2129642
- J Korean Med Sci.
- 2015 Feb;30(2):140-144.
- doi: 10.3346/jkms.2015.30.2.140
Coal workers' pneumoconiosis (CWP) is characterized as a chronic inflammation of the lung associated with activation of macrophages and endothelial cells in the lung. The aim of the present study... -
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- The relationship between serum adiponectin and inflammatory cytokines in obese Korean juveniles
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Byun SH, Kwon EB, Kim SY
- KMID: 2284643
- Korean J Pediatr.
- 2014 Dec;57(12):533-537.
- doi: 10.3345/kjp.2014.57.12.533
PURPOSE: Obesity is related to systemic inflammatory processes causing cardiovascular complications. Intercellular adhesion molecule-1 (ICAM-1), CD40 ligand (CD40L), P-selectin are newly described mediators of inflammation and have a significant effect... -
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